Evaluation of a portable hyperspectral imager for medical imaging applications

Portable hyperspectral imagers are becoming commonly available as a commercial product. A liquid crystal tunable filter based CCD imager was evaluated and characterized for spectral stray light using a tunable laser facility. The hyperspectral imager is currently being used to investigate the use of hyperspectral imaging in medical applications. This paper discusses the imager design and performance, the characterization of this system, and medical imaging as a related application. Imagers of this type may be fundamental to transferring radiometric scales using a hyperspectral image projector. The use of the hyperspectral imager for use with a hyperspectral image projector is also discussed.

[1]  M. Gladwin,et al.  Noninvasive Determination of Spatially Resolved and Time-Resolved Tissue Perfusion in Humans During Nitric Oxide Inhibition and Inhalation by Use of a Visible-Reflectance Hyperspectral Imaging Technique , 2001, Circulation.

[2]  Jessica A. Faust,et al.  Imaging Spectroscopy and the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) , 1998 .

[3]  A F Goetz,et al.  Imaging Spectrometry for Earth Remote Sensing , 1985, Science.

[4]  Yuqin Zong,et al.  Simple spectral stray light correction method for array spectroradiometers. , 2006, Applied optics.

[5]  Richard E. Poulson,et al.  Test Methods in Spectrophotometry: Stray-Light Determination , 1964 .

[6]  Wei Chen,et al.  Ocean PHILLS hyperspectral imager: design, characterization, and calibration. , 2002, Optics express.

[7]  Jeffrey H. Bowles,et al.  Calibration of inexpensive pushbroom imaging spectrometers , 1998 .

[8]  K. Zuzak,et al.  Visible reflectance hyperspectral imaging: characterization of a noninvasive, in vivo system for determining tissue perfusion. , 2002, Analytical chemistry.

[9]  Steven W. Brown,et al.  Hyperspectral image projector for advanced sensor characterization , 2006, SPIE Optics + Photonics.

[10]  George P Eppeldauer,et al.  Facility for spectral irradiance and radiance responsivity calibrations using uniform sources. , 2006, Applied optics.

[11]  M. Descour,et al.  Demonstration of a computed-tomography imaging spectrometer using a computer-generated hologram disperser. , 1997, Applied optics.

[12]  Tuan Vo-Dinh,et al.  Development of an Advanced Hyperspectral Imaging (HSI) System with Applications for Cancer Detection , 2006, Annals of Biomedical Engineering.

[13]  I. Young,et al.  Calibration and Characterisation of Imaging Spectrographs , 2003 .

[14]  Steven W. Brown,et al.  Hyperspectral image projectors for radiometric applications , 2006 .

[15]  Steven W. Brown,et al.  Correction of Stray Light In Spectroradiometers and Imaging Instruments | NIST , 2007 .

[16]  William E. Roper,et al.  Hyperspectral imaging applied to medical diagnoses and food safety , 2003, SPIE Defense + Commercial Sensing.

[17]  J. Romier,et al.  Imaging spectrometer based on an acousto-optic tunable filter , 1998 .

[18]  David Kohler,et al.  New approach for the radiometric calibration of spectral imaging systems. , 2004, Optics express.

[19]  Nahum Gat,et al.  Imaging spectroscopy using tunable filters: a review , 2000, SPIE Defense + Commercial Sensing.

[20]  Warren S. Grundfest,et al.  The use of spectral imaging for the diagnosis of retinal disease , 1999, 1999 IEEE LEOS Annual Meeting Conference Proceedings. LEOS'99. 12th Annual Meeting. IEEE Lasers and Electro-Optics Society 1999 Annual Meeting (Cat. No.99CH37009).