Progress and challenges in biomaterials used for bone tissue engineering: bioactive glasses and elastomeric composites

[1]  Robert Langer,et al.  Principles of tissue engineering , 2014 .

[2]  Hideto Tsuji,et al.  Poly(Lactic Acid) , 2013 .

[3]  Larry L. Hench,et al.  An Introduction to Bioceramics , 2013 .

[4]  G. Thouas,et al.  Biodegradable soft elastomers: synthesis/properties of materials and fabrication of scaffolds , 2012 .

[5]  Michael Szycher,et al.  Szycher's Handbook of Polyurethanes , 2012 .

[6]  Qizhi Chen,et al.  A comparative study on in vitro enzymatic degradation of poly(glycerol sebacate) and poly(xylitol sebacate) , 2012 .

[7]  Lei Zhang,et al.  Incorporation of B2O3 in CaO-SiO2-P2O5 bioactive glass system for improving strength of low-temperature co-fired porous glass ceramics , 2012 .

[8]  K. Khor,et al.  Spark plasma sintering of sol–gel derived 45S5 Bioglass®-ceramics: Mechanical properties and biocompatibility evaluation , 2012 .

[9]  D. Day,et al.  Long-term conversion of 45S5 bioactive glass–ceramic microspheres in aqueous phosphate solution , 2012, Journal of Materials Science: Materials in Medicine.

[10]  Changsheng Liu,et al.  Characteristics and biocompatibility of Na2O–K2O–CaO–MgO–SrO–B2O3–P2O5 borophosphate glass fibers , 2012 .

[11]  Qizhi Chen,et al.  Optimization of Bioglass® Scaffold Fabrication Process , 2011 .

[12]  G. Simon,et al.  Manipulation of mechanical compliance of elastomeric PGS by incorporation of halloysite nanotubes for soft tissue engineering applications. , 2011, Journal of the mechanical behavior of biomedical materials.

[13]  W. Cook,et al.  In vitro enzymatic degradation of poly (glycerol sebacate)-based materials. , 2011, Biomaterials.

[14]  Q. Chen,et al.  Foaming technology of tissue engineering scaffolds - a review , 2011 .

[15]  Y. Sogo,et al.  Synthesis and characterization of hierarchically macroporous and mesoporous CaO-MO-SiO(2)-P(2)O(5) (M=Mg, Zn, Sr) bioactive glass scaffolds. , 2011, Acta biomaterialia.

[16]  G. Thouas,et al.  Fabrication and characterization of sol-gel derived 45S5 Bioglass®-ceramic scaffolds. , 2011, Acta biomaterialia.

[17]  G. Thouas,et al.  Synthesis and characterisation of poly(glycerol sebacate)-co-lactic acid as surgical sealants , 2011 .

[18]  Delbert E Day,et al.  Bioactive glass in tissue engineering. , 2011, Acta biomaterialia.

[19]  Aldo R Boccaccini,et al.  A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics. , 2011, Biomaterials.

[20]  C. Werner Polymers for Regenerative Medicine , 2010 .

[21]  G. Thouas,et al.  Bone‐Like Elastomer‐Toughened Scaffolds with Degradability Kinetics Matching Healing Rates of Injured Bone , 2010 .

[22]  W. Cook,et al.  The mechanical characteristics and in vitro biocompatibility of poly(glycerol sebacate)-bioglass elastomeric composites. , 2010, Biomaterials.

[23]  Q. Fu,et al.  Silicate, borosilicate, and borate bioactive glass scaffolds with controllable degradation rate for bone tissue engineering applications. I. Preparation and in vitro degradation. , 2010, Journal of biomedical materials research. Part A.

[24]  R. Langer,et al.  Biodegradable xylitol-based elastomers: in vivo behavior and biocompatibility. , 2010, Journal of biomedical materials research. Part A.

[25]  P. Komesaroff,et al.  A new sol-gel process for producing Na(2)O-containing bioactive glass ceramics. , 2010, Acta biomaterialia.

[26]  Keiichi Kuroki,et al.  Silicate, borosilicate, and borate bioactive glass scaffolds with controllable degradation rate for bone tissue engineering applications. II. In vitro and in vivo biological evaluation. , 2010, Journal of biomedical materials research. Part A.

[27]  E. Stanley,et al.  Elastomeric nanocomposites as cell delivery vehicles and cardiac support devices , 2010 .

[28]  Wenhai Huang,et al.  Teicoplanin-loaded borate bioactive glass implants for treating chronic bone infection in a rabbit tibia osteomyelitis model. , 2010, Biomaterials.

[29]  K. Clarke,et al.  Magnetic resonance imaging evaluation of remodeling by cardiac elastomeric tissue scaffold biomaterials in a rat model of myocardial infarction. , 2010, Tissue engineering. Part A.

[30]  J. Nyman,et al.  Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit. , 2010, Acta biomaterialia.

[31]  Scott J. Hollister,et al.  Tailoring the mechanical properties of 3D-designed poly(glycerol sebacate) scaffolds for cartilage applications. , 2010, Journal of biomedical materials research. Part A.

[32]  S. Balaji,et al.  A Novel Biocompatible Poly (3-hydroxy-co-4-hydroxybutyrate) Blend as a Potential Biomaterial for Tissue Engineering , 2010 .

[33]  J. Guan,et al.  Tailoring the degradation kinetics of poly(ester carbonate urethane)urea thermoplastic elastomers for tissue engineering scaffolds. , 2010, Biomaterials.

[34]  Je-Yong Choi,et al.  Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation. , 2010, Bone.

[35]  P. Marie The calcium-sensing receptor in bone cells: a potential therapeutic target in osteoporosis. , 2010, Bone.

[36]  Xia Li,et al.  The vacuolar ATPase in bone cells: a potential therapeutic target in osteoporosis , 2010, Molecular Biology Reports.

[37]  C. Doillon,et al.  The stimulation of angiogenesis and collagen deposition by copper. , 2010, Biomaterials.

[38]  C. Sundback,et al.  Degradation behavior of poly(glycerol sebacate). , 2009, Journal of biomedical materials research. Part A.

[39]  Deping Wang,et al.  In vitro evaluation of borate-based bioactive glass scaffolds prepared by a polymer foam replication method , 2009 .

[40]  T. Uysal,et al.  Stimulation of bone formation by dietary boron in an orthopedically expanded suture in rabbits. , 2009, The Angle orthodontist.

[41]  J. E. Mark Polymer Data Handbook , 2009 .

[42]  William L. Neeley,et al.  Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation. , 2009, Biomaterials.

[43]  S. Ramakrishna,et al.  Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts. , 2009, Biomaterials.

[44]  M. Barbosa,et al.  Engineering endochondral bone: in vivo studies. , 2009, Tissue engineering. Part A.

[45]  S. Vogt,et al.  COPPER AND ANGIOGENESIS: UNRAVELLING A RELATIONSHIP KEY TO CANCER PROGRESSION , 2009, Clinical and experimental pharmacology & physiology.

[46]  Robert Langer,et al.  Biodegradable poly(polyol sebacate) polymers. , 2008, Biomaterials.

[47]  John Banhart,et al.  Porous Metals and Metallic Foams: Current Status and Recent Developments , 2008 .

[48]  P Ducheyne,et al.  Bioactive glass particulate material as a filler for bone lesions. , 2008, Journal of oral rehabilitation.

[49]  G. Wnek,et al.  Encyclopedia of biomaterials and biomedical engineering , 2008 .

[50]  Robert Langer,et al.  Biodegradable Xylitol‐Based Polymers , 2008 .

[51]  F. Nielsen Is boron nutritionally relevant? , 2008, Nutrition reviews.

[52]  D. Day,et al.  Conversion of Bioactive Silicate (45S5), Borate, and Borosilicate Glasses to Hydroxyapatite in Dilute Phosphate Solution , 2008 .

[53]  S. Guelcher,et al.  Biodegradable polyurethanes: synthesis and applications in regenerative medicine. , 2008, Tissue engineering. Part B, Reviews.

[54]  Qizhi Chen,et al.  Biomaterials in cardiac tissue engineering: Ten years of research survey , 2008 .

[55]  R. Nerem,et al.  Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells. , 2007, Journal of biomedical materials research. Part A.

[56]  A. Hiltner,et al.  Biodegradation mechanisms of polyurethane elastomers , 2007 .

[57]  Katherine D Kavlock,et al.  Synthesis and characterization of segmented poly(esterurethane urea) elastomers for bone tissue engineering. , 2007, Acta biomaterialia.

[58]  Michael S Sacks,et al.  An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in subacute myocardial infarction. , 2007, Journal of the American College of Cardiology.

[59]  Yi Hong,et al.  Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization. , 2007, Biomaterials.

[60]  Maurilio Marcacci,et al.  Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. , 2007, Tissue engineering.

[61]  Yuqing Wu,et al.  FTIR Spectroscopic Study on the Interaction between a Fluoroionophore and Metal Ions , 2007, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[62]  Giuditta Perozzi,et al.  Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. , 2007, American journal of physiology. Lung cellular and molecular physiology.

[63]  A. R. Boccaccini,et al.  The surface functionalization of 45S5 Bioglass®-based glass-ceramic scaffolds and its impact on bioactivity , 2006, Journal of materials science. Materials in medicine.

[64]  Delara Motlagh,et al.  Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering. , 2006, Biomaterials.

[65]  Wenhai Huang,et al.  Kinetics and mechanisms of the conversion of silicate (45S5), borate, and borosilicate glasses to hydroxyapatite in dilute phosphate solutions , 2006, Journal of materials science. Materials in medicine.

[66]  Sylwester Gogolewski,et al.  Regeneration of bicortical defects in the iliac crest of estrogen-deficient sheep, using new biodegradable polyurethane bone graft substitutes. , 2006, Journal of biomedical materials research. Part A.

[67]  R. Cabrini,et al.  Biological performance of boron-modified bioactive glass particles implanted in rat tibia bone marrow , 2006, Biomedical materials.

[68]  A. Boccaccini,et al.  Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. , 2006, Biomaterials.

[69]  A. Boccaccini,et al.  Coupling Mechanical Competence and Bioresorbability in Bioglass®‐Derived Tissue Engineering Scaffolds , 2006 .

[70]  Robert Langer,et al.  Microfabrication of poly (glycerol-sebacate) for contact guidance applications. , 2006, Biomaterials.

[71]  Aldo R Boccaccini,et al.  45S5 Bioglass-derived glass-ceramic scaffolds for bone tissue engineering. , 2006, Biomaterials.

[72]  F. Nielsen,et al.  A histomorphometric study of alveolar bone modeling and remodeling in mice fed a boron‐deficient diet , 2006, Archives of oral biology.

[73]  Robert Langer,et al.  Three‐Dimensional Microfluidic Tissue‐Engineering Scaffolds Using a Flexible Biodegradable Polymer , 2006, Advanced materials.

[74]  K. Woodhouse,et al.  Understanding the biodegradation of polyurethanes: from classical implants to tissue engineering materials. , 2005, Biomaterials.

[75]  K. Woodhouse,et al.  Polyurethane films seeded with embryonic stem cell-derived cardiomyocytes for use in cardiac tissue engineering applications. , 2005, Biomaterials.

[76]  M. Yamaguchi,et al.  Effects of copper on bone component in the femoral tissues of rats: anabolic effect of zinc is weakened by copper. , 2005, Biological & pharmaceutical bulletin.

[77]  Guoqiang Chen,et al.  The application of polyhydroxyalkanoates as tissue engineering materials. , 2005, Biomaterials.

[78]  A R Boccaccini,et al.  Mechanical properties of highly porous PDLLA/Bioglass composite foams as scaffolds for bone tissue engineering. , 2005, Acta biomaterialia.

[79]  Helen H. Lu,et al.  Compositional effects on the formation of a calcium phosphate layer and the response of osteoblast-like cells on polymer-bioactive glass composites. , 2005, Biomaterials.

[80]  Jiang Chang,et al.  Fabrication, Characterization, and in vitro Degradation of Composite Scaffolds Based on PHBV and Bioactive Glass , 2005, Journal of biomaterials applications.

[81]  D. Kaplan,et al.  Porosity of 3D biomaterial scaffolds and osteogenesis. , 2005, Biomaterials.

[82]  Joseph P Vacanti,et al.  Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. , 2005, Biomaterials.

[83]  Meital Zilberman,et al.  Mechanical properties and in vitro degradation of bioresorbable fibers and expandable fiber-based stents. , 2005, Journal of biomedical materials research. Part B, Applied biomaterials.

[84]  J. Guan,et al.  Synthesis, characterization and cytocompatibility of polyurethaneurea elastomers with designed elastase sensitivity. , 2005, Biomacromolecules.

[85]  W. Mittelmeier,et al.  Biomechanical and allergological characteristics of a biodegradable poly(D,L‐lactic acid) coating for orthopaedic implants , 2005, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[86]  Hussila Keshaw,et al.  Release of angiogenic growth factors from cells encapsulated in alginate beads with bioactive glass. , 2005, Biomaterials.

[87]  Antonios G Mikos,et al.  In vitro degradation of porous poly(propylene fumarate)/poly(DL-lactic-co-glycolic acid) composite scaffolds. , 2005, Biomaterials.

[88]  Michael S Sacks,et al.  Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications. , 2005, Biomaterials.

[89]  Il Keun Kwon,et al.  Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential. , 2005, Biomaterials.

[90]  Guo-Qiang Chen,et al.  Effects of crystallization of polyhydroxyalkanoate blend on surface physicochemical properties and interactions with rabbit articular cartilage chondrocytes. , 2005, Biomaterials.

[91]  D. Cohn,et al.  Designing biodegradable multiblock PCL/PLA thermoplastic elastomers. , 2005, Biomaterials.

[92]  G. Reilly,et al.  Borate Glass Supports the In Vitro Osteogenic Differentiation of Human Mesenchymal Stem Cells , 2005 .

[93]  Jun Yao,et al.  The effect of bioactive glass content on synthesis and bioactivity of composite poly (lactic-co-glycolic acid)/bioactive glass substrate for tissue engineering. , 2005, Biomaterials.

[94]  I. A. Jones,et al.  Preparation of poly(ε-caprolactone)/continuous bioglass fibre composite using monomer transfer moulding for bone implant , 2005 .

[95]  Robert Langer,et al.  Endothelialized microvasculature based on a biodegradable elastomer. , 2005, Tissue engineering.

[96]  Aldo R Boccaccini,et al.  Assessment of polyglycolic acid mesh and bioactive glass for soft-tissue engineering scaffolds. , 2004, Biomaterials.

[97]  L. Guan,et al.  Preparation and characterization of a highly macroporous biodegradable composite tissue engineering scaffold. , 2004, Journal of biomedical materials research. Part A.

[98]  S. Waldman,et al.  Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. , 2004, Tissue engineering.

[99]  C. Stamm,et al.  Mechanical and structural properties of a novel hybrid heart valve scaffold for tissue engineering. , 2004, Artificial organs.

[100]  Jiang Chang,et al.  Preparation and characterization of bioactive and biodegradable Wollastonite/poly(D,L-lactic acid) composite scaffolds , 2004, Journal of materials science. Materials in medicine.

[101]  William R Wagner,et al.  Fabrication of biodegradable elastomeric scaffolds with sub-micron morphologies. , 2004, Journal of biomedical materials research. Part A.

[102]  A. Göpferich,et al.  Biomimetic polymers in pharmaceutical and biomedical sciences. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[103]  J. Leong,et al.  Ultrastructural study of mineralization of a strontium-containing hydroxyapatite (Sr-HA) cement in vivo. , 2004, Journal of biomedical materials research. Part A.

[104]  Lorenz Meinel,et al.  Localized delivery of growth factors for bone repair. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[105]  A R Boccaccini,et al.  Porous poly(alpha-hydroxyacid)/Bioglass composite scaffolds for bone tissue engineering. I: Preparation and in vitro characterisation. , 2004, Biomaterials.

[106]  J. Leong,et al.  Strengthening mechanisms of bone bonding to crystalline hydroxyapatite in vivo. , 2004, Biomaterials.

[107]  Aldo R Boccaccini,et al.  PDLLA/Bioglass composites for soft-tissue and hard-tissue engineering: an in vitro cell biology assessment. , 2004, Biomaterials.

[108]  M. Kellomäki,et al.  In vitro and in vivo behavior of self-reinforced bioabsorbable polymer and self-reinforced bioabsorbable polymer/bioactive glass composites. , 2004, Journal of biomedical materials research. Part A.

[109]  Cato T Laurencin,et al.  Novel polymer-synthesized ceramic composite-based system for bone repair: an in vitro evaluation. , 2004, Journal of biomedical materials research. Part A.

[110]  A. Batchelor,et al.  An Introduction to Biocomposites , 2004 .

[111]  L. Francis,et al.  Processing and properties of porous poly(L-lactide)/bioactive glass composites. , 2004, Biomaterials.

[112]  Jian Yang,et al.  Biodegradable polyester elastomers in tissue engineering , 2004, Expert opinion on biological therapy.

[113]  R. Reis,et al.  Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments , 2004 .

[114]  C. Simon,et al.  Self-hardening calcium phosphate cement-mesh composite: reinforcement, macropores, and cell response. , 2004, Journal of biomedical materials research. Part A.

[115]  A. Boccaccini,et al.  Novel Bioresorbable Poly(lactide-co-glycolide) (PLGA) and PLGA/Bioglass ® Composite Tubular Foam Scaffolds for Tissue Engineering Applications , 2004 .

[116]  Carl G Simon,et al.  Self‐hardening calcium phosphate composite scaffold for bone tissue engineering , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[117]  J. A. Planell,et al.  Development and cell response of a new biodegradable composite scaffold for guided bone regeneration , 2004, Journal of materials science. Materials in medicine.

[118]  Jonathan C Knowles,et al.  Hydroxyapatite/poly(epsilon-caprolactone) composite coatings on hydroxyapatite porous bone scaffold for drug delivery. , 2004, Biomaterials.

[119]  Y. Gong,et al.  Studies on bone marrow stromal cells affinity of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate). , 2004, Biomaterials.

[120]  Shozo Takagi,et al.  Synergistic reinforcement of in situ hardening calcium phosphate composite scaffold for bone tissue engineering. , 2004, Biomaterials.

[121]  W. Bonfield,et al.  Mechanical properties of glass-ceramic A-W-polyethylene composites: effect of filler content and particle size. , 2004, Biomaterials.

[122]  Qiong Wu,et al.  Attachment, proliferation and differentiation of osteoblasts on random biopolyester poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds. , 2004, Biomaterials.

[123]  Julian R Jones,et al.  Factors affecting the structure and properties of bioactive foam scaffolds for tissue engineering. , 2004, Journal of biomedical materials research. Part B, Applied biomaterials.

[124]  A. Boccaccini,et al.  In vitro evaluation of novel bioactive composites based on Bioglass-filled polylactide foams for bone tissue engineering scaffolds. , 2003, Journal of biomedical materials research. Part A.

[125]  Aldo R. Boccaccini,et al.  Bioresorbable and bioactive polymer/Bioglass® composites with tailored pore structure for tissue engineering applications , 2003 .

[126]  R Borojevic,et al.  Characterization of a bovine collagen-hydroxyapatite composite scaffold for bone tissue engineering. , 2003, Biomaterials.

[127]  Xiu-lan Li,et al.  Preparation and characterization of macroporous chitosan-gelatin/beta-tricalcium phosphate composite scaffolds for bone tissue engineering. , 2003, Journal of biomedical materials research. Part A.

[128]  David P. Martin,et al.  Medical applications of poly-4-hydroxybutyrate: a strong flexible absorbable biomaterial , 2003 .

[129]  C. Guoqiang,et al.  Effects of surface morphology on the biocompatibility of polyhydroxyalkanoates , 2003 .

[130]  Y. Ikada,et al.  First Evidence That Bone Marrow Cells Contribute to the Construction of Tissue-Engineered Vascular Autografts In Vivo , 2003, Circulation.

[131]  GokiMatsumura,et al.  First Evidence That Bone Marrow Cells Contribute to the Construction of Tissue-Engineered Vascular Autografts In Vivo , 2003 .

[132]  Hui Ma,et al.  Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro. , 2003, Biomaterials.

[133]  Todd C McDevitt,et al.  Spatially organized layers of cardiomyocytes on biodegradable polyurethane films for myocardial repair. , 2003, Journal of biomedical materials research. Part A.

[134]  A R Boccaccini,et al.  Preparation, characterization, and in vitro degradation of bioresorbable and bioactive composites based on Bioglass-filled polylactide foams. , 2003, Journal of biomedical materials research. Part A.

[135]  Masayuki Nogami,et al.  Preparation of poly(lactic acid) composites containing calcium carbonate (vaterite). , 2003, Biomaterials.

[136]  Robert M Nerem,et al.  Mechanical strain-stimulated remodeling of tissue-engineered blood vessel constructs. , 2003, Tissue engineering.

[137]  Larry L. Hench,et al.  Regeneration of trabecular bone using porous ceramics , 2003 .

[138]  Robert Langer,et al.  In vivo degradation characteristics of poly(glycerol sebacate). , 2003, Journal of biomedical materials research. Part A.

[139]  Young Ha Kim,et al.  Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. , 2003, Journal of biomedical materials research. Part A.

[140]  Darren J. Martin,et al.  Designing Biostable Polyurethane Elastomers for Biomedical Implants , 2003 .

[141]  Narutoshi Hibino,et al.  Successful application of tissue engineered vascular autografts: clinical experience. , 2003, Biomaterials.

[142]  Masakazu Kawashita,et al.  Novel bioactive materials with different mechanical properties. , 2003, Biomaterials.

[143]  W. Bonfield,et al.  Apatite-forming ability of glass-ceramic apatite–wollastonite – polyethylene composites: effect of filler content , 2003, Journal of materials science. Materials in medicine.

[144]  R. Adhikari,et al.  Biodegradable synthetic polymers for tissue engineering. , 2003, European cells & materials.

[145]  A R Boccaccini,et al.  Bioresorbable and bioactive composite materials based on polylactide foams filled with and coated by Bioglass® particles for tissue engineering applications , 2003, Journal of materials science. Materials in medicine.

[146]  Jan P. Stegemann,et al.  Phenotype Modulation in Vascular Tissue Engineering Using Biochemical and Mechanical Stimulation , 2003, Annals of Biomedical Engineering.

[147]  Jinchao Zhang,et al.  Effects of Cu2+ and pH on osteoclastic bone resorption in vitro , 2003 .

[148]  R. Ritchie,et al.  Mechanistic fracture criteria for the failure of human cortical bone , 2003, Nature materials.

[149]  Guoqiang Chen,et al.  Polyhydroxyalkanoate (PHA) scaffolds with good mechanical properties and biocompatibility. , 2003, Biomaterials.

[150]  Cato T Laurencin,et al.  Three-dimensional, bioactive, biodegradable, polymer-bioactive glass composite scaffolds with improved mechanical properties support collagen synthesis and mineralization of human osteoblast-like cells in vitro. , 2003, Journal of biomedical materials research. Part A.

[151]  Simon C Watkins,et al.  Vascularization and tissue infiltration of a biodegradable polyurethane matrix. , 2003, Journal of biomedical materials research. Part A.

[152]  Zhong Zheng,et al.  Induced production of rabbit articular cartilage-derived chondrocyte collagen II on polyhydroxyalkanoate blends , 2003, Journal of biomaterials science. Polymer edition.

[153]  W. Bonfield,et al.  Mechanical Properties of Glass-Ceramic A-W - Polyethylene Composites: Effect of Filler Content , 2002 .

[154]  A. Boccaccini,et al.  Novel bioresorbable and bioactive composites based on bioactive glass and polylactide foams for bone tissue engineering , 2002, Journal of materials science. Materials in medicine.

[155]  P. Hu,et al.  Study on the three-dimensional proliferation of rabbit articular cartilage-derived chondrocytes on polyhydroxyalkanoate scaffolds. , 2002, Biomaterials.

[156]  S. Agarwal,et al.  Synthesis, biodegradability, and biocompatibility of lysine diisocyanate-glucose polymers. , 2002, Tissue engineering.

[157]  P. Ducheyne,et al.  In vivo evaluation of a bioactive scaffold for bone tissue engineering. , 2002, Journal of biomedical materials research.

[158]  K. Gisselfält,et al.  Synthesis and properties of degradable poly(urethane urea)s to be used for ligament reconstructions. , 2002, Biomacromolecules.

[159]  R. Langer,et al.  A tough biodegradable elastomer , 2002, Nature Biotechnology.

[160]  Larry L. Hench,et al.  Broad-Spectrum Bactericidal Activity of Ag2O-Doped Bioactive Glass , 2002, Antimicrobial Agents and Chemotherapy.

[161]  Antonios G Mikos,et al.  Biomaterials and Scaffolds in Reparative Medicine , 2002, Annals of the New York Academy of Sciences.

[162]  Linda G Griffith,et al.  Emerging Design Principles in Biomaterials and Scaffolds for Tissue Engineering , 2002, Annals of the New York Academy of Sciences.

[163]  D O Slosman,et al.  Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. , 2002, The Journal of clinical endocrinology and metabolism.

[164]  Jukka Seppälä,et al.  In vitro evaluation of poly(ε-caprolactone-co-DL-lactide)/bioactive glass composites , 2002 .

[165]  R. Langer,et al.  Poly(glycerol sebacate)—A Novel Biodegradable Elastomer for Tissue Engineering , 2002 .

[166]  A. Lindahl,et al.  Studies of polyurethane urea bands for ACL reconstruction , 2002, Journal of materials science. Materials in medicine.

[167]  J. Hubbell,et al.  Poly(ethylene glycol) block copolymers. , 2002, Journal of biotechnology.

[168]  A. Boccaccini,et al.  Novel Biodegradable Polymer/Bioactive Glass Composites for Tissue Engineering Applications , 2002 .

[169]  M. Akhter,et al.  Skeletal unloading and dietary copper depletion are detrimental to bone quality of mature rats. , 2002, The Journal of nutrition.

[170]  D. Fyhrie,et al.  Finite element calculated uniaxial apparent stiffness is a consistent predictor of uniaxial apparent strength in human vertebral cancellous bone tested with different boundary conditions. , 2001, Journal of biomechanics.

[171]  K. Leong,et al.  The design of scaffolds for use in tissue engineering. Part I. Traditional factors. , 2001, Tissue engineering.

[172]  J. Hao,et al.  Preparation and mechanical properties of nanocomposites of poly(D,L-lactide) with Ca-deficient hydroxyapatite nanocrystals. , 2001, Biomaterials.

[173]  Alyssa Panitch,et al.  Polymeric biomaterials for tissue and organ regeneration , 2001 .

[174]  D. Vashishth,et al.  Trabecular shear stress in human vertebral cancellous bone: intra- and inter-individual variations. , 2001, Journal of biomechanics.

[175]  C. Rey,et al.  Mechanisms of Action and Therapeutic Potential of Strontium in Bone , 2001, Calcified Tissue International.

[176]  E. Wintermantel,et al.  Degradation of poly(D,L)lactide implants with or without addition of calciumphosphates in vivo. , 2001, Biomaterials.

[177]  A. S. Dunn,et al.  The influence of polymer blend composition on the degradation of polymer/hydroxyapatite biomaterials , 2001, Journal of materials science. Materials in medicine.

[178]  J. Strain,et al.  No effect of copper supplementation on biochemical markers of bone metabolism in healthy young adult females despite apparently improved copper status , 2001, European Journal of Clinical Nutrition.

[179]  E B Giesen,et al.  Mechanical properties of cancellous bone in the human mandibular condyle are anisotropic. , 2001, Journal of biomechanics.

[180]  L L Hench,et al.  Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass 45S5 dissolution. , 2001, Journal of biomedical materials research.

[181]  H. Uludaǧ,et al.  Growth Factor Delivery for Bone Tissue Engineering , 2001, Journal of drug targeting.

[182]  K. Burg,et al.  Biomaterial developments for bone tissue engineering. , 2000, Biomaterials.

[183]  J C Middleton,et al.  Synthetic biodegradable polymers as orthopedic devices. , 2000, Biomaterials.

[184]  Larry L. Hench,et al.  Bioglass ®45S5 Stimulates Osteoblast Turnover and Enhances Bone Formation In Vitro: Implications and Applications for Bone Tissue Engineering , 2000, Calcified Tissue International.

[185]  J. Polak,et al.  Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis. , 2000, Biochemical and biophysical research communications.

[186]  Y. Kimura,et al.  Synthesis and characterization of hydroxy-terminated [RS]-poly(3-hydroxybutyrate) and its utilization to block copolymerization with l-lactide to obtain a biodegradable thermoplastic elastomer , 2000 .

[187]  Antonios G. Mikos,et al.  Formation of highly porous biodegradable scaffolds for tissue engineering , 2000 .

[188]  M J Yaszemski,et al.  Effects of transforming growth factor beta1 released from biodegradable polymer microparticles on marrow stromal osteoblasts cultured on poly(propylene fumarate) substrates. , 2000, Journal of biomedical materials research.

[189]  D J Mooney,et al.  Scaffolds for engineering smooth muscle under cyclic mechanical strain conditions. , 2000, Journal of biomechanical engineering.

[190]  M. Kellomäki,et al.  Processing and properties of two different poly (ortho esters) , 2000, Journal of materials science. Materials in medicine.

[191]  E. Sudmann,et al.  Biocompatibility and effect on osteogenesis of poly(ortho ester) compared to poly(DL-lactic acid). , 2000, Journal of biomedical materials research.

[192]  P. Ducheyne,et al.  Evaluation of osteoblast response to porous bioactive glass (45S5) substrates by RT-PCR analysis. , 2000, Tissue engineering.

[193]  E. Martuscelli,et al.  Review Properties of blends and composites based on poly(3-hydroxy)butyrate (PHB) and poly(3-hydroxybutyrate-hydroxyvalerate) (PHBV) copolymers , 2000 .

[194]  M A Moses,et al.  Tissue engineering of autologous aorta using a new biodegradable polymer. , 1999, The Annals of thoracic surgery.

[195]  W. Bonfield,et al.  Biodegradable drug delivery system for the treatment of bone infection and repair , 1999, Journal of materials science. Materials in medicine.

[196]  R J Zdrahala,et al.  Biomedical Applications of Polyurethanes: A Review of Past Promises, Present Realities, and a Vibrant Future , 1999, Journal of biomaterials applications.

[197]  R Langer,et al.  Functional arteries grown in vitro. , 1999, Science.

[198]  P. Ma,et al.  Poly(alpha-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology. , 1999, Journal of biomedical materials research.

[199]  J. Jagur-grodzinski Biomedical application of functional polymers , 1999 .

[200]  P. Aebischer,et al.  In vivo performance of a new biodegradable polyester urethane system used as a nerve guidance channel. , 1998, Biomaterials.

[201]  A. Pennings,et al.  A new biomedical polyurethane with a high modulus based on 1,4-butanediisocyanate and ε-caprolactone , 1998, Journal of materials science. Materials in medicine.

[202]  A. J. Pennings,et al.  High molecular weight polyurethanes and a polyurethane urea based on 1,4-butanediisocyanate , 1998 .

[203]  T. Kokubo Novel Biomedical Materials Based on Glasses , 1998 .

[204]  A. Mikos,et al.  In vivo degradation of a poly(propylene fumarate)/beta-tricalcium phosphate injectable composite scaffold. , 1998, Journal of biomedical materials research.

[205]  G. Hu Copper stimulates proliferation of human endothelial cells under culture , 1998, Journal of cellular biochemistry.

[206]  Ilhan A. Aksay,et al.  Biomaterials is this really a field of research , 1998 .

[207]  R J Cousins,et al.  A role of zinc in the regulation of gene expression , 1998, Proceedings of the Nutrition Society.

[208]  L. Hench,et al.  In vitro adsorption and activity of enzymes on reaction layers of bioactive glass substrates. , 1998, Journal of biomedical materials research.

[209]  Joseph Kost,et al.  Handbook of Biodegradable Polymers , 1998 .

[210]  L. Hench Sol-gel materials for bioceramic applications , 1997 .

[211]  P. Neuenschwander,et al.  Development of degradable polyesterurethanes for medical applications: in vitro and in vivo evaluations. , 1997, Journal of biomedical materials research.

[212]  N. Lang,et al.  The biological effect of natural bone mineral on bone neoformation on the rabbit skull. , 1997, Clinical oral implants research.

[213]  V. Koivisto,et al.  Metabolic response to lactitol and xylitol in healthy men. , 1997, The American journal of clinical nutrition.

[214]  H. Ohgushi,et al.  Osteogenic differentiation of cultured marrow stromal stem cells on the surface of bioactive glass ceramics. , 1996, Journal of biomedical materials research.

[215]  A. Kalangos,et al.  Preliminary clinical results of implantation of biodegradable pericardial substitute in pediatric open heart operations. , 1996, The Journal of thoracic and cardiovascular surgery.

[216]  Buddy D. Ratner,et al.  Biomaterials Science: An Introduction to Materials in Medicine , 1996 .

[217]  L. Hench,et al.  In-vitro protein interactions with a bioactive gel-glass , 1996 .

[218]  C T Laurencin,et al.  Tissue engineered bone-regeneration using degradable polymers: the formation of mineralized matrices. , 1996, Bone.

[219]  R J Zdrahala,et al.  Small Caliber Vascular Grafts. Part II: Polyurethanes Revisited , 1996, Journal of biomaterials applications.

[220]  L L Hench,et al.  Effect of crystallization on apatite-layer formation of bioactive glass 45S5. , 1996, Journal of biomedical materials research.

[221]  H R Allcock,et al.  A highly porous 3-dimensional polyphosphazene polymer matrix for skeletal tissue regeneration. , 1996, Journal of biomedical materials research.

[222]  K. Ellwood Methods available to estimate the energy values of sugar alcohols. , 1995, The American journal of clinical nutrition.

[223]  S. Bowald,et al.  A Biodegradable Patch used as a Pericardial Substitute after Cardiac Surgery: 6- and 24-Month Evaluation with CT , 1995, The Thoracic and cardiovascular surgeon.

[224]  C T Laurencin,et al.  Osteoblast-like cell adherance and migration through 3-dimensional porous polymer matrices. , 1995, Biochemical and biophysical research communications.

[225]  H. Abe,et al.  Microbial synthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) , 1995 .

[226]  W. Hayes,et al.  The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold. , 1995, Tissue engineering.

[227]  C. Friedman,et al.  Synthetic bone graft substitutes. , 1994, Otolaryngologic clinics of North America.

[228]  A. Clark,et al.  Calcium phosphate formation on sol-gel-derived bioactive glasses in vitro. , 1994, Journal of biomedical materials research.

[229]  G. Valdrè,et al.  Analysis of the in vivo reactions of a bioactive glass in soft and hard tissue. , 1994, Biomaterials.

[230]  W. Vogel,et al.  MACHINEABLE AND PHOSPHATE GLASS-CERAMICS , 1993 .

[231]  T. Kokubo A/W GLASS-CERAMIC: PROCESSING AND PROPERTIES , 1993 .

[232]  H R Allcock,et al.  Use of polyphosphazenes for skeletal tissue regeneration. , 1993, Journal of biomedical materials research.

[233]  W C de Bruijn,et al.  Foreign body reactions to resorbable poly(L-lactide) bone plates and screws used for the fixation of unstable zygomatic fractures. , 1993, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[234]  F. Zhang,et al.  The effect of residual glassy phase in a bioactive glass-ceramic on the formation of its surface apatite layerin vitro , 1992 .

[235]  W. Bonfield,et al.  In vitro and in vivo evaluation of polyhydroxybutyrate and of polyhydroxybutyrate reinforced with hydroxyapatite. , 1991, Biomaterials.

[236]  Larry L. Hench,et al.  Bioceramics: From Concept to Clinic , 1991 .

[237]  E Bell,et al.  Tissue engineering: a perspective , 1991, Journal of cellular biochemistry.

[238]  J O Hollinger,et al.  Biodegradable bone repair materials. Synthetic polymers and ceramics. , 1986, Clinical orthopaedics and related research.

[239]  L. Sestoft,et al.  An Evaluation of Biochemical Aspects of Intravenous Fructose, Sorbitol and Xylitol Administration in Man , 1985, Acta anaesthesiologica Scandinavica. Supplementum.

[240]  L L Hench,et al.  Surface-active biomaterials. , 1984, Science.

[241]  L L Hench,et al.  Toxicology and biocompatibility of bioglasses. , 1981, Journal of biomedical materials research.

[242]  G L Kimmel,et al.  Aliphatic polyesters II. The degradation of poly (DL-lactide), poly (epsilon-caprolactone), and their copolymers in vivo. , 1981, Biomaterials.

[243]  P. Klopper,et al.  Tissue response to dense apatite implants in rats. , 1980, Journal of biomedical materials research.

[244]  Larry L. Hench,et al.  Bonding mechanisms at the interface of ceramic prosthetic materials , 1971 .

[245]  Tabatabaei Qomi,et al.  The Design of Scaffolds for Use in Tissue Engineering , 2014 .

[246]  C. Charalambous Calcium Phosphate Ceramics as Hard Tissue Prosthetics , 2014 .

[247]  Changyou Gao,et al.  Incorporation of B 2 O 3 in CaO-SiO 2P 2 O 5 bioactive glass system for improving strength of low-temperature cofi red porous glass ceramics , 2012 .

[248]  S. Kakar,et al.  Biology and Enhancement of Skeletal Repair , 2009 .

[249]  D. Schüler,et al.  Synthesis and Characterization , 2009 .

[250]  Aldo R Boccaccini,et al.  Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue. , 2008, Biomaterials.

[251]  S. Gogolewski,et al.  Biodegradable polyurethane cancellous bone graft substitutes in the treatment of iliac crest defects. , 2007, Journal of biomedical materials research. Part A.

[252]  D. Day,et al.  In Vitro Bioactive Characteristics of Borate‐Based Glasses with Controllable Degradation Behavior , 2007 .

[253]  D. Day,et al.  Mechanisms for converting bioactive silicate, borate, and borosilicate glasses to hydroxyapatite in dilute phosphate solution , 2006 .

[254]  T. Freier Biopolyesters in tissue engineering applications , 2006 .

[255]  Anthony Atala,et al.  Methods Of Tissue Engineering , 2006 .

[256]  Koichi Masuda,et al.  Chapter 62: TISSUE ENGINEERING FOR REGENERATION AND REPLACEMENT OF THE INTERVERTEBRAL DISC , 2006 .

[257]  C. Laurencin,et al.  Low temperature formation of hydroxyapatite-poly(alkyl oxybenzoate)phosphazene composites for biomedical applications. , 2005, Biomaterials.

[258]  Aldo R. Boccaccini,et al.  Preparation and characterisation of poly(lactide-co-glycolide) (PLGA) and PLGA/Bioglass® composite tubular foam scaffolds for tissue engineering applications , 2005 .

[259]  N. Peppas,et al.  Structure and Interactions in Covalently and Ionically Crosslinked Chitosan Hydrogels for Biomedical Applications , 2003 .

[260]  R. Langer,et al.  Biodegradable Microfluidic Scaffolds for Vascular Tissue Engineering , 2004 .

[261]  Jeffrey Y. Shyu,et al.  In vitro and in vivo biocompatibility analysis of poly (glycerol sebacate) as a potential nerve guide material , 2004 .

[262]  HuangJian,et al.  Effects of Cu^2+ and pH on osteoclastic bone resorption in vitro , 2003 .

[263]  B. Browner,et al.  Skeletal trauma: basic science, Management and reconstruction , 2003 .

[264]  J. Rodríguez,et al.  Modulation of the proliferation and differentiation of human mesenchymal stem cells by copper , 2002, Journal of cellular biochemistry.

[265]  Paul A. Williams,et al.  Bioceramics : proceedings of the 14th International Symposium on Ceramics in Medicine, the annual meeting of the International Society for Ceramics in Medicine : Bioceramics-14, Palm Springs, California, USA, 14-17th November 2001 , 2002 .

[266]  X Zhang,et al.  Bone induction by porous glass ceramic made from Bioglass (45S5). , 2001, Journal of biomedical materials research.

[267]  M. Nogami,et al.  Preparation and mechanical properties of polylactic acid composites containing hydroxyapatite fibers. , 2001, Biomaterials.

[268]  C T Laurencin,et al.  A novel amorphous calcium phosphate polymer ceramic for bone repair: I. Synthesis and characterization. , 2001, Journal of biomedical materials research.

[269]  Larry L. Hench,et al.  Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass t 45 S 5 dissolution , 2000 .

[270]  V. Thomas,et al.  Synthesis of hydrolytically stable low elastic modulus polyurethane‐urea for biomedical applications , 2000 .

[271]  Tang Shun-qing Progress in biomaterials , 2000 .

[272]  G. Beaupré,et al.  Skeletal Tissue Regeneration , 2000 .

[273]  J. Tanaka,et al.  Cell culture test of TCP/CPLA composite. , 1999, Journal of biomedical materials research.

[274]  James F. Shackelford,et al.  Bioceramics, applications of ceramic and glass materials in medicine , 1999 .

[275]  Masayoshi Yamaguchi,et al.  Role of zinc in bone formation and bone resorption , 1998 .

[276]  P Zioupos,et al.  Changes in the stiffness, strength, and toughness of human cortical bone with age. , 1998, Bone.

[277]  L. Hench,et al.  Properties of bioactive glasses and glass-ceramics , 1998 .

[278]  M. Sefton,et al.  Tissue engineering. , 1998, Journal of cutaneous medicine and surgery.

[279]  Jonathan Black,et al.  Handbook of Biomaterial Properties , 1998, Springer US.

[280]  Eleonora Winkelhausen,et al.  Microbial conversion of d-xylose to xylitol , 1998 .

[281]  A. E. Simone Porous metals and metallic foams , 1997 .

[282]  B. Gladen,et al.  The effects of dietary boron on bone strength in rats. , 1997, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[283]  C T Laurencin,et al.  Three-dimensional degradable porous polymer-ceramic matrices for use in bone repair. , 1996, Journal of biomaterials science. Polymer edition.

[284]  H. Winet,et al.  Acidity near eroding polylactide-polyglycolide in vitro and in vivo in rabbit tibial bone chambers. , 1996, Biomaterials.

[285]  F. Trotta,et al.  PREPARATION AND CHARACTERIZATION OF , 1996 .

[286]  W C de Bruijn,et al.  Late degradation tissue response to poly(L-lactide) bone plates and screws. , 1995, Biomaterials.

[287]  L Pinchuk,et al.  A review of the biostability and carcinogenicity of polyurethanes in medicine and the new generation of 'biostable' polyurethanes. , 1994, Journal of biomaterials science. Polymer edition.

[288]  H. Griesser Degradation of polyurethanes in biomedical applications—A review , 1991 .

[289]  L. Hench,et al.  CRC handbook of bioactive ceramics , 1990 .

[290]  C. Fred Fox,et al.  Tissue engineering : proceedings of a workshop held at Granlibakken, Lake Tahoe, California, February 26-29, 1988 , 1988 .

[291]  R. Doremus,et al.  Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface. , 1977, Journal of bioengineering.

[292]  K. Maier,et al.  Zum Metabolismus von Glukose, Fruktose, Sorbit und Xylit beim Menschen , 1973 .