Recent advances in voltammetric, amperometric and ion-selective (bio)sensors fabricated by microengineering manufacturing approaches

Summary Over the last few years, microengineering fabrication approaches, originating from the semiconductor manufacturing technology, have been increasingly used for the development of electrochemical (bio)sensors and analytical devices. The application of various microengineering technologies enables the rapid mass fabrication of low-cost and disposable sensors of small size with uniform and strictly controlled geometry and surface properties and provides wide scope for device miniaturization and integration. This work will focus on the latest developments of microfabricated voltammetric, amperometric and ion-selective sensors with representative applications to organic/gas analysis, ion detection, biosensing/wearable devices and electrochemical imaging/in-vivo sensing.

[1]  M. Triantafyllou,et al.  Miniaturized chemical sensor with bio-inspired micropillar working electrode array for lead detection , 2016 .

[2]  Zheyao Wang,et al.  Silicon nanowire pH sensors fabricated with CMOS compatible sidewall mask technology , 2019, Sensors and Actuators B: Chemical.

[3]  M. Rigoulet,et al.  Microwell array integrating nanoelectrodes for coupled opto-electrochemical monitorings of single mitochondria. , 2019, Biosensors & bioelectronics.

[4]  P. Arumugam,et al.  Electrochemical behavior of a gold nanoring electrode microfabricated on a silicon micropillar , 2019, Sensors and Actuators B: Chemical.

[5]  G. Swain,et al.  Isatin Detection Using a Boron-Doped Diamond 3-in-1 Sensing Platform. , 2018, Analytical chemistry.

[6]  Jun Wang,et al.  Lithographic Microfabrication of a 16-Electrode Array on a Probe Tip for High Spatial Resolution Electrochemical Localization of Exocytosis. , 2016, Analytical chemistry.

[7]  Donghyun Lee,et al.  Electrochemical detection of dopamine using periodic cylindrical gold nanoelectrode arrays , 2018, Scientific Reports.

[8]  M. Vojs,et al.  Bismuth modified boron doped diamond electrode for simultaneous determination of Zn, Cd and Pb ions by square wave anodic stripping voltammetry: Influence of boron concentration and surface morphology , 2019, Vacuum.

[9]  Seok Jae Lee,et al.  Flexible nanopillar-based electrochemical sensors for genetic detection of foodborne pathogens , 2018, Nano Convergence.

[10]  Haiyu Li,et al.  Simultaneous determination of lead, arsenic, and mercury in cosmetics using a plastic based disposable electrochemical sensor , 2019, Microchemical Journal.

[11]  Qun Zhou,et al.  Array of recessed gold nanoelectrodes formed with polymethylmethacrylate for individual detection of ascorbic acid, dopamine and uric acid , 2016 .

[12]  R. Keynton,et al.  Measurement of As(III) with in situ subtraction of background and interferent signals by double potential step-anodic stripping coulometry , 2019 .

[13]  A. Errachid,et al.  A fully integrated passive microfluidic Lab-on-a-Chip for real-time electrochemical detection of ammonium: Sewage applications. , 2019, The Science of the total environment.

[14]  R. Chen,et al.  Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip. , 2016, ChemNanoMat : chemistry of nanomaterials for energy, biology and more.

[15]  Hak Soo Choi,et al.  Single Microfluidic Electrochemical Sensor System for Simultaneous Multi-Pulmonary Hypertension Biomarker Analyses , 2017, Scientific Reports.

[16]  Ali Javey,et al.  A Wearable Microfluidic Sensing Patch for Dynamic Sweat Secretion Analysis. , 2018, ACS sensors.

[17]  Sam Emaminejad,et al.  Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis , 2016, Nature.

[18]  T. Cui,et al.  Ultrasensitive micro ion selective sensor arrays for multiplex heavy metal ions detection , 2018, Microsystem Technologies.

[19]  Manabu Kinoshita,et al.  Microfluidic device coupled with a microfabricated oxygen electrode for the measurement of bactericidal activity of neutrophil-like cells. , 2017, Analytica chimica acta.

[20]  Lei Zheng,et al.  Highly sensitive solution-gated graphene transistor based sensor for continuous and real-time detection of free chlorine. , 2018, Analytica chimica acta.

[21]  Christos Kokkinos,et al.  Integrated on-chip sensor with sputtered Ag-Au-Au electrodes for the voltammetric determination of trace Hg(II) , 2019, Sensors and Actuators B: Chemical.

[22]  M. Madou.  Fundamentals of microfabrication : the science of miniaturization , 2002 .

[23]  T. Pan,et al.  Super-Nernstian sensitivity in microfabricated electrochemical pH sensor based on CeTi x O y film for biofluid monitoring , 2018 .

[24]  M. Allen,et al.  A Micromachined Freestanding Electrochemical Sensor for Measuring Dissolved Oxygen , 2019, Journal of Microelectromechanical Systems.

[25]  D. H. Nguyen,et al.  Stable Electrochemical Measurements of Platinum Screen-Printed Electrodes Modified with Vertical ZnO Nanorods for Bacterial Detection , 2019, Journal of Nanomaterials.

[26]  Jinyoung Jeong,et al.  Fabrication of Pyrrole‐Based Electrochemical Biosensor Platform Using Nanoimprint Lithography , 2018 .

[27]  Heungjoo Shin,et al.  An electrochemical immunosensor based on a 3D carbon system consisting of a suspended mesh and substrate-bound interdigitated array nanoelectrodes for sensitive cardiac biomarker detection. , 2018, Biosensors & bioelectronics.

[28]  Changqing Yi,et al.  Simultaneous detection of glucose, uric acid and cholesterol using flexible microneedle electrode array-based biosensor and multi-channel portable electrochemical analyzer , 2019, Sensors and Actuators B: Chemical.

[29]  K. Ino,et al.  Development of Oxygen Consumption Analysis with an on-Chip Electrochemical Device and Simulation. , 2017, Analytical chemistry.

[30]  P. Olivero,et al.  Micro graphite-patterned diamond sensors: Towards the simultaneous in vitro detection of molecular release and action potentials generation from excitable cells , 2019, Carbon.

[31]  Choul-Young Kim,et al.  Implementation of Smart Dressing Systems Based on Flexible pH Sensors Using PET Films , 2019, IEICE Trans. Inf. Syst..

[32]  K. Ino,et al.  Combination of Double-Mediator System with Large-Scale Integration-Based Amperometric Devices for Detecting NAD(P)H:quinone Oxidoreductase 1 Activity of Cancer Cell Aggregates. , 2019, ACS sensors.

[33]  Zhihong Li,et al.  An Integrated Device for Monitoring Single Cell Metabolism , 2019, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII).

[34]  J. Park,et al.  A miniaturized and flexible cadmium and lead ion detection sensor based on micro-patterned reduced graphene oxide/carbon nanotube/bismuth composite electrodes , 2018 .

[35]  Y. Ohno,et al.  An interdigitated electrode with dense carbon nanotube forests on conductive supports for electrochemical biosensors. , 2018, The Analyst.

[36]  S. Hemanth,et al.  Suspended 3D pyrolytic carbon microelectrodes for electrochemistry , 2017 .

[37]  J. Joseph,et al.  A miniaturized electrochemical platform with an integrated PDMS reservoir for label-free DNA hybridization detection using nanostructured Au electrodes. , 2019, The Analyst.

[38]  M. Becker,et al.  Indium Tin Oxide Film Characteristics for Cathodic Stripping Voltammetry. , 2019, ACS applied materials & interfaces.

[39]  Donny Nugraha Mazaafrianto,et al.  Label-Free Electrochemical Sensor for Ochratoxin A Using a Microfabricated Electrode with Immobilized Aptamer , 2018, ACS Omega.

[40]  J. Lee,et al.  Redox cycling-based electrochemical-enzymatic biosensor platform fabricated via electrodeposition of gold nanoparticles on carbon IDA nanoelectrodes , 2017, 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS).

[41]  T. Matsue,et al.  Redox cycling-based electrochemical CMOS imaging sensor for real time and selective imaging of redox analytes , 2020 .

[42]  Heungjoo Shin,et al.  Gold Nanostructure Decorated 3D Porous Carbon Architectures as a Non-Enzymatic Glucose Sensor , 2019, 2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS).

[43]  A. Hierlemann,et al.  Microfabrication techniques for chemical/biosensors , 2003, Proc. IEEE.

[44]  W. Heineman,et al.  Determination of Lead with a Copper-Based Electrochemical Sensor. , 2017, Analytical chemistry.

[45]  Rafiq Ahmad,et al.  Nonenzymatic flexible field-effect transistor based glucose sensor fabricated using NiO quantum dots modified ZnO nanorods. , 2018, Journal of colloid and interface science.

[46]  Yujie Zhu,et al.  Bench-Top Fabrication of an All-PDMS Microfluidic Electrochemical Cell Sensor Integrating Micro/Nanostructured Electrodes , 2017, Sensors.

[47]  Pavel Neužil,et al.  Nanostructured Gold Microelectrode Array for Ultrasensitive Detection of Heavy Metal Contamination. , 2018, Analytical chemistry.

[48]  D. Giokas,et al.  Paper-based device with a sputtered tin-film electrode for the voltammetric determination of Cd(II) and Zn(II) , 2018 .

[49]  Göran Stemme,et al.  Real-time intradermal continuous glucose monitoring using a minimally invasive microneedle-based system , 2018, Biomedical microdevices.

[50]  A. Economou,et al.  Microfabricated chip integrating a bismuth microelectrode array for the determination of trace cobalt(II) by adsorptive cathodic stripping voltammetry , 2016 .

[51]  Kumi Y. Inoue,et al.  Electrochemicolor Imaging Using an LSI-Based Device for Multiplexed Cell Assays. , 2017, Analytical chemistry.

[52]  M. Pemble,et al.  A highly sensitive glucose biosensor based on a micro disk array electrode design modified with carbon quantum dots and gold nanoparticles , 2019, Electrochimica Acta.