Unsuccessful and Successful Clinical Trials in Acute Respiratory Distress Syndrome: Addressing Physiology-Based Gaps
暂无分享,去创建一个
[1] V. Novack,et al. Effect of Esophageal Pressure-Guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome: A Risk-Based and Mechanistic Reanalysis of the EPVent-2 Trial. , 2021, American journal of respiratory and critical care medicine.
[2] J. Laffey,et al. Personalized mechanical ventilation in acute respiratory distress syndrome , 2021, Critical Care.
[3] R. Kacmarek,et al. Weaning patients with obesity from ventilatory support , 2021, Current opinion in critical care.
[4] A. Girbes,et al. Between-trial heterogeneity in ARDS research , 2021, Intensive Care Medicine.
[5] A. Mebazaa,et al. Designing an ARDS trial for 2020 and beyond: focus on enrichment strategies , 2020, Intensive Care Medicine.
[6] B. Rochwerg,et al. Standardized Care Is Better Than Individualized Care for the Majority of Critically Ill Patients. , 2020, Critical care medicine.
[7] Arthur S Slutsky,et al. Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis. , 2020, JAMA.
[8] N. Habashi,et al. A Physiologically Informed Strategy to Effectively Open, Stabilize, and Protect the Acutely Injured Lung , 2020, Frontiers in Physiology.
[9] J. González-Martín,et al. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. , 2020, The Lancet. Respiratory medicine.
[10] R. Kacmarek,et al. A lung rescue team improves survival in obesity with acute respiratory distress syndrome , 2020, Critical Care.
[11] J. Vincent,et al. Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review. , 2019, Critical care medicine.
[12] J. Fraser,et al. Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP): A Phase II, Multicenter, Randomized, Controlled Trial. , 2019, American journal of respiratory and critical care medicine.
[13] J. Villar,et al. PEEP titration guided by transpulmonary pressure: lessons from a negative trial. , 2019, Journal of thoracic disease.
[14] Arthur S Slutsky,et al. Early Paralytic Agents for ARDS? Yes, No, and Sometimes. , 2019, The New England journal of medicine.
[15] David T. Huang,et al. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. , 2019, The New England journal of medicine.
[16] D. Cook,et al. Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure–Guided Strategy vs an Empirical High PEEP-FIO2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial , 2019, JAMA.
[17] M. A. Romera,et al. A Prognostic Enrichment Strategy for Selection of Patients With Acute Respiratory Distress Syndrome in Clinical Trials , 2019, Critical care medicine.
[18] E. Fan,et al. Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis. , 2019, The Lancet. Respiratory medicine.
[19] L. Papazian,et al. Variability of reverse triggering in deeply sedated ARDS patients , 2019, Intensive Care Medicine.
[20] D. Brodie,et al. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome , 2018, The New England journal of medicine.
[21] R. Kacmarek,et al. Should the ART trial change our practice? , 2017, Journal of thoracic disease.
[22] J. Vincent,et al. Comparison of the efficacy and safety of FP-1201-lyo (intravenously administered recombinant human interferon beta-1a) and placebo in the treatment of patients with moderate or severe acute respiratory distress syndrome: study protocol for a randomized controlled trial , 2017, Trials.
[23] M. Amato,et al. Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial , 2017, JAMA.
[24] Arthur S Slutsky,et al. Severity of Hypoxemia and Effect of High‐Frequency Oscillatory Ventilation in Acute Respiratory Distress Syndrome , 2017, American journal of respiratory and critical care medicine.
[25] J. Vincent. High-Frequency Oscillation in Acute Respiratory Distress Syndrome. The End of the Story? , 2017, American journal of respiratory and critical care medicine.
[26] R. Kacmarek,et al. Transpulmonary Pressure Describes Lung Morphology During Decremental Positive End-Expiratory Pressure Trials in Obesity* , 2017, Critical care medicine.
[27] G. Perkins,et al. Individual patient data analysis of tidal volumes used in three large randomized control trials involving patients with acute respiratory distress syndrome , 2017, British Journal of Anaesthesia.
[28] G. Van den Berghe,et al. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. , 2017, Critical care medicine.
[29] M. Balaan,et al. Acute Respiratory Distress Syndrome , 2016, Critical care nursing quarterly.
[30] Arthur S Slutsky,et al. Happy 50th birthday ARDS! , 2016, Intensive Care Medicine.
[31] R. Kacmarek,et al. Recruitment Maneuvers and Positive End-Expiratory Pressure Titration in Morbidly Obese ICU Patients , 2016, Critical care medicine.
[32] J. Borges,et al. Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial* , 2016, Critical care medicine.
[33] G. Perkins,et al. Simvastatin in the acute respiratory distress syndrome. , 2014, The New England journal of medicine.
[34] R. Kacmarek,et al. Clinical trials in patients with the acute respiratory distress syndrome: Burn after reading , 2014, Intensive Care Medicine.
[35] S. Jalkanen,et al. The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study. , 2014, The Lancet. Respiratory medicine.
[36] D. Talmor,et al. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis , 2014, Intensive Care Medicine.
[37] Arthur S Slutsky,et al. Ventilator-induced lung injury. , 2013, The New England journal of medicine.
[38] S. Jaber,et al. Prone positioning in severe acute respiratory distress syndrome. , 2013, The New England journal of medicine.
[39] Duncan Young,et al. High-Frequency Oscillation for Acute Respiratory Distress Syndrome , 2013 .
[40] Arthur S Slutsky,et al. High-frequency oscillation in early acute respiratory distress syndrome. , 2013, The New England journal of medicine.
[41] Arthur S Slutsky,et al. Acute Respiratory Distress Syndrome The Berlin Definition , 2012 .
[42] G. Perkins,et al. Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial , 2012, The Lancet.
[43] J. Villar. What Is the Acute Respiratory Distress Syndrome? , 2011, Respiratory Care.
[44] B. Yegneswaran,et al. Neuromuscular blockers and ARDS: Thou shalt not breathe, move, or die! , 2011, Critical care.
[45] W. Bos,et al. Dexamethasone and length of hospital stay in patients with community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial , 2011, The Lancet.
[46] V. Leray,et al. Efficacy and safety of recruitment maneuvers in acute respiratory distress syndrome , 2011, Annals of intensive care.
[47] A. Loundou,et al. Neuromuscular blockers in early acute respiratory distress syndrome. , 2010, The New England journal of medicine.
[48] Z. Puthucheary,et al. Neuromuscular blockers and ARDS. , 2010, New England Journal of Medicine.
[49] David Alvis. Happy 50th birthday. , 2009, Ophthalmology.
[50] Atul Malhotra,et al. Mechanical ventilation guided by esophageal pressure in acute lung injury. , 2008, The New England journal of medicine.
[51] Jesús Blanco,et al. An early PEEP/FIO2 trial identifies different degrees of lung injury in patients with acute respiratory distress syndrome. , 2007, American journal of respiratory and critical care medicine.
[52] Arthur S Slutsky,et al. Understanding high-frequency oscillation: lessons from the animal kingdom , 2007, Intensive Care Medicine.
[53] Stephan H. Böhm,et al. Use of dynamic compliance for open lung positive end‐expiratory pressure titration in an experimental study , 2007, Critical care medicine.
[54] J. Cidlowski,et al. Antiinflammatory action of glucocorticoids--new mechanisms for old drugs. , 2005, The New England journal of medicine.
[55] Luciano Gattinoni,et al. The concept of “baby lung” , 2005, Intensive Care Medicine.
[56] R. Kacmarek,et al. Why are physicians so skeptical about positive randomized controlled clinical trials in critical care medicine? , 2005, Intensive Care Medicine.
[57] S. Colgan,et al. Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia , 2004, The Journal of experimental medicine.
[58] D. Schoenfeld,et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. , 2000, The New England journal of medicine.
[59] M. Graham,et al. Mechanism by which the prone position improves oxygenation in acute lung injury. , 1994, American journal of respiratory and critical care medicine.
[60] M. Lamy,et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. , 1994, American journal of respiratory and critical care medicine.
[61] J. Cooper,et al. Ten-year experience with extracorporeal membrane oxygenation for severe respiratory failure. , 1988, Chest.
[62] R. Light,et al. The Adult Respiratory Distress Syndrome and Pancuronium Bromide , 1975, Anesthesia and analgesia.