Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.

[1]  P. Reichard,et al.  Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cells , 1987, Molecular and cellular biology.

[2]  P. Reichard.  Regulation of deoxyribotide synthesis. , 1987, Biochemistry.

[3]  L. R. Finch,et al.  Degradation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human leukemic myeloblasts and lymphoblasts. , 1987, Cancer research.

[4]  A. Fridland,et al.  Mechanism for ara-CTP catabolism in human leukemic cells and effect of deaminase inhibitors on this process. , 1987, Seminars in oncology.

[5]  E. Estey,et al.  Saturation of 1-β-d-Arabinofuranosylcytosine 5′-Triphosphate Accumulation in Leukemia Cells during High-Dose 1-β-d-Arabinofuranosylcytosine Therapy , 1987 .

[6]  S. Greer,et al.  Protective, tumor-selective dual pathway activation of 5-fluoro-2'-deoxycytidine provided by tetrahydrouridine in mice bearing mammary adenocarcinoma-755. , 1987, Cancer research.

[7]  W. Plunkett,et al.  Regulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in human leukemia cells by deoxycytidine 5'-triphosphate. , 1986, Cancer research.

[8]  S. Eriksson,et al.  Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of thymidine on wild-type and dCMP deaminase-deficient mouse S49 T-lymphoma cells. , 1984, Experimental cell research.

[9]  M. Rossi,et al.  Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase. , 1984, Molecular pharmacology.

[10]  P. Saunders,et al.  Nucleoside kinase activities of Chinese hamster ovary cells. , 1983, Biochimica et biophysica acta.

[11]  C. Heidelberger,et al.  Therapeutic response of leukemic mice treated with fluorinated pyrimidines and inhibitors of deoxyuridylate synthesis. , 1982, Biochemical pharmacology.

[12]  B. Chabner,et al.  Deoxycytidylate deaminase. Purification and some properties of the enzyme isolated from human spleen. , 1981, The Journal of biological chemistry.

[13]  B. Barlogie,et al.  Simultaneous determination of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 3-deazauridine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography. , 1980, Journal of chromatography.

[14]  Y. Rustum,et al.  Effect of thymidine on the toxicity, antitumor activity, and metabolism of 1-beta-D-arabinofuranosylcytosine in rats bearing a chemically induced colon carcinoma. , 1980, Cancer research.

[15]  G. Buttin,et al.  The modulation of the thymidine triphosphate pool of Chinese hamster cells by dCMP deaminase and UDP reductase. Thymidine auxotrophy induced by CTP in dCMP deaminase-deficient lines. , 1980, The Journal of biological chemistry.

[16]  L Thelander,et al.  Allosteric regulation of calf thymus ribonucleoside diphosphate reductase. , 1979, Biochemistry.

[17]  R. Jackson.  The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine. , 1978, The Journal of biological chemistry.

[18]  B. Chabner,et al.  Pyrimidine nucleoside monophosphate kinase from human leukemic blast cells. , 1978, Cancer research.

[19]  David F. Wentworth,et al.  On the interaction of 3,4,5,6-tetrahydrouridine with human liver cytidine deaminase. , 1975, Biochemistry.

[20]  R. Wolfenden,et al.  Cytidine deaminase from Escherichia coli. Purification, properties and inhibition by the potential transition state analog 3,4,5,6-tetrahydrouridine. , 1971, The Journal of biological chemistry.

[21]  G. Maley,et al.  Tetrahydrodeoxyuridylate: a potent inhibitor of deoxycytidylate deaminase. , 1971, Archives of biochemistry and biophysics.

[22]  Y. Cheng,et al.  Erythrocytic nucleoside diphosphokinase. IV. Evidence for electrophoretic heterogeneity. , 1971, Biochemistry.

[23]  G. Neil,et al.  Enhancement by tetrahydrouridine of 1-beta-D-arabinofuranosylcytosine (cytarabine) oral activity in L1210 leukemic mice. , 1970, Cancer research.

[24]  D. Ives,et al.  Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme. , 1970, The Journal of biological chemistry.

[25]  G. W. Camiener.  Studies of the enzymatic deamination of ara-cytidine. V. inhibition in vitro and in vivo by tetrahydrouridine and other reduced pyrimidine nucleosides. , 1968, Biochemical pharmacology.

[26]  R. Momparler,et al.  Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside. , 1968, The Journal of biological chemistry.

[27]  A. R. Hanze.  Nucleic acids. IV. The catalytic reduction of pyrimidine nucleosides (human liver deaminase inhibitors). , 1967, Journal of the American Chemical Society.

[28]  Moore Ec,et al.  Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors , 1966 .

[29]  H. Neu,et al.  NUCLEOTIDE SEQUENCE ANALYSIS OF POLYRIBONUCLEOTIDES BY MEANS OF PERIODATE OXIDATION FOLLOWED BY CLEAVAGE WITH AN AMINE. , 1964, The Journal of biological chemistry.

[30]  Y. Cheng,et al.  Human deoxycytidylate deaminase. Substrate and regulator specificities and their chemotherapeutic implications. , 1983, Molecular pharmacology.

[31]  G. Buttin,et al.  Studies on 1-β-D-arabinofuranosyl cytosine-resistant mutants of Chinese hamster fibroblasts: III. Joint resistance to arabinofuranosyl cytosine and to excess thymidine—A semidominant manifestation of deoxycytidine triphosphate pool expansion , 1979, Somatic cell genetics.

[32]  G. Maley,et al.  The Regulatory Influence of Allosteric Effectors on Deoxycytidylate Deaminases , 1972 .

[33]  R. Momparler,et al.  Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside. , 1968, Biochimica et biophysica acta.