The Channel Attention based Context Encoder Network for Inner Limiting Membrane Detection

The optic disc segmentation is an important step for retinal image-based disease diagnosis such as glaucoma. The inner limiting membrane (ILM) is the first boundary in the OCT, which can help to extract the retinal pigment epithelium (RPE) through gradient edge information to locate the boundary of the optic disc. Thus, the ILM layer segmentation is of great importance for optic disc localization. In this paper, we build a new optic disc centered dataset from 20 volunteers and manually annotated the ILM boundary in each OCT scan as ground-truth. We also propose a channel attention based context encoder network modified from the CE-Net to segment the optic disc. It mainly contains three phases: the encoder module, the channel attention based context encoder module, and the decoder module. Finally, we demonstrate that our proposed method achieves state-of-the-art disc segmentation performance on our dataset mentioned above.

[1]  Yue Wu,et al.  Deep-Learning Based, Automated Segmentation of Macular Edema in Optical Coherence Tomography , 2017, bioRxiv.

[2]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[3]  Stephen Lin,et al.  Automatic Optic Disc Detection in OCT Slices via Low-Rank Reconstruction , 2015, IEEE Transactions on Biomedical Engineering.

[4]  Shenghua Gao,et al.  CE-Net: Context Encoder Network for 2D Medical Image Segmentation , 2019, IEEE Transactions on Medical Imaging.

[5]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[6]  Richard Socher,et al.  Improving Generalization Performance by Switching from Adam to SGD , 2017, ArXiv.

[7]  Peng Liu,et al.  DeepDisc: Optic Disc Segmentation Based on Atrous Convolution and Spatial Pyramid Pooling , 2018, COMPAY/OMIA@MICCAI.

[8]  Yue Wu,et al.  Deep-Learning Based, Automated Segmentation of Macular Edema in Optical Coherence Tomography , 2017, bioRxiv.

[9]  T. Wong,et al.  Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. , 2014, Ophthalmology.

[10]  Juan Xu,et al.  Optic disk feature extraction via modified deformable model technique for glaucoma analysis , 2007, Pattern Recognit..

[11]  Joseph M. Schmitt,et al.  Optical coherence tomography (OCT): a review , 1999 .

[12]  Dacheng Tao,et al.  Sparse Dissimilarity-Constrained Coding for Glaucoma Screening , 2015, IEEE Transactions on Biomedical Engineering.

[13]  Jiang Liu,et al.  Automatic glaucoma diagnosis through medical imaging informatics , 2013 .

[14]  Gang Sun,et al.  Squeeze-and-Excitation Networks , 2017, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.