A chart review on surgical myocardial debridging in symptomatic patients: a safe procedure with good long-term clinical outcome and coronary computed tomographic angiography results

Abstract OBJECTIVES Myocardial bridging is mostly diagnosed as an incidental imaging finding but can result in severe vessel compression and significant clinical adverse complications. Since there is still an ongoing debate when to propose surgical unroofing, we studied a group of patients where this was performed as an isolated procedure. METHODS In 16 patients (38.9 ± 15.7 years, 75% men) who had surgical unroofing for symptomatic isolated myocardial bridges of the left anterior descending artery, we retrospectively analysed symptomatology, medication, imaging modalities used, operative techniques, complications and long-term outcome. Computed tomographic fractional flow reserve was calculated to understand its potential value for decision-making. RESULTS Most procedures were performed on-pump (75%, mean cardiopulmonary bypass 56.5 ± 27.9 min, mean aortic cross-clamping 36.4 ± 19.7 min). Three patients needed a left internal mammary artery bypass since the artery dived inside the ventricle. There were no major complications or deaths. The mean follow-up was 5.5 years. Although there was a dramatic improvement in symptoms, still 31% experienced atypical chest pain at various moments during follow-up. Postoperative radiological control was performed in 88%, showing no residual compression or recurrent myocardial bridge and patent bypass if performed. All postoperative computed tomographic flow calculations (7) showed a normalization of coronary flow. CONCLUSIONS Surgical unroofing for symptomatic isolated myocardial bridging is a safe procedure. Patient selection remains difficult but introducing standard coronary computed tomographic angiography with flow calculations could be helpful in preoperative decision-making and during follow-up.

[1]  Theresa M. Beckie,et al.  2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. , 2021, Circulation.

[2]  Samin K. Sharma,et al.  Myocardial Bridging: Diagnosis, Functional Assessment, and Management: JACC State-of-the-Art Review. , 2021, Journal of the American College of Cardiology.

[3]  Jiayin Zhang,et al.  CT Fractional Flow Reserve for the Diagnosis of Myocardial Bridging-Related Ischemia: A Study Using Dynamic CT Myocardial Perfusion Imaging as a Reference Standard , 2021, Korean Journal of Radiology.

[4]  Qingyu Wu,et al.  Surgical intervention and outcome for treatment of myocardial bridging refractory to medication , 2021, Journal of cardiac surgery.

[5]  Camille E. Hironaka,et al.  Off-Pump Mini Thoracotomy Versus Sternotomy for Left Anterior Descending Myocardial Bridge Unroofing. , 2020, Annals of Thoracic Surgery.

[6]  R. Tubbs,et al.  Myocardial bridges: A meta‐analysis , 2020, Clinical anatomy.

[7]  C. Lavie,et al.  An updated review on myocardial bridging. , 2020, Cardiovascular revascularization medicine : including molecular interventions.

[8]  H. Schaff,et al.  Clinical Outcomes of Surgical Unroofing of Myocardial Bridging in Symptomatic Patients. , 2020, The Annals of thoracic surgery.

[9]  U. Schoepf,et al.  Diagnostic Performance of Machine Learning Based CT-FFR in Detecting Ischemia in Myocardial Bridging and Concomitant Proximal Atherosclerotic Disease. , 2019, The Canadian journal of cardiology.

[10]  F. Gaita,et al.  What is the optimal treatment for symptomatic patients with isolated coronary myocardial bridge? A systematic review and pooled analysis , 2017, Journal of cardiovascular medicine.

[11]  R. S. Mitchell,et al.  Surgical Unroofing of Hemodynamically Significant Left Anterior Descending Myocardial Bridges. , 2017, The Annals of thoracic surgery.

[12]  Filippo Cademartiri,et al.  Left Anterior Descending Artery Myocardial Bridging: A Clinical Approach. , 2016, Journal of the American College of Cardiology.

[13]  J. Spertus,et al.  Development and Validation of a Short Version of the Seattle Angina Questionnaire , 2014, Circulation. Cardiovascular quality and outcomes.

[14]  T. Athanasiou,et al.  Is coronary artery bypass grafting an acceptable alternative to myotomy for the treatment of myocardial bridging? , 2013, Interactive cardiovascular and thoracic surgery.

[15]  S. Möhlenkamp,et al.  Myocardial bridging: a congenital variant as an anatomic risk factor for myocardial infarction? , 2009, Circulation.

[16]  R. Erbel,et al.  Myocardial bridging detection by non-invasive multislice spiral computed tomography: comparison with intravascular ultrasound. , 2008, Chinese medical journal.

[17]  Qingyu Wu,et al.  Surgical treatment of myocardial bridging: report of 31 cases. , 2007, Chinese medical journal.

[18]  Sheng-Shou Hu,et al.  Surgical outcome and clinical follow-up in patients with symptomatic myocardial bridging. , 2007, Chinese medical journal.

[19]  S. Flamm,et al.  Coronary anomalies: incidence, pathophysiology, and clinical relevance. , 2002, Circulation.

[20]  T. O. Cheng Myocardial bridging in a young patient with sudden death , 1997, Clinical cardiology.

[21]  J. Sullebarger,et al.  Myocardial infarction associated with myocardial bridging: case history and review of the literature. , 1997, Catheterization and cardiovascular diagnosis.

[22]  H. Crijns,et al.  Myocardial bridging in a survivor of sudden cardiac near-death: role of intracoronary doppler flow measurements and angiography during dobutamine stress in the clinical evaluation. , 1997, Heart.

[23]  R A Deyo,et al.  Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease. , 1995, Journal of the American College of Cardiology.

[24]  J. Shani,et al.  Exercise-induced ventricular tachycardia in association with a myocardial bridge. , 1991, Chest.

[25]  P. Brugada,et al.  Myocardial bridging as a cause of paroxysmal atrioventricular block. , 1983, Journal of the American College of Cardiology.

[26]  E. Arbustini,et al.  Myocardial bridges and ischemic heart disease. , 1980, European heart journal.

[27]  E. Hannan,et al.  Invited commentary. , 2015, The Annals of thoracic surgery.

[28]  N. Marchionni,et al.  Myocardial stunning associated with a myocardial bridge. , 2002, International journal of cardiology.