Based on the investigation and research on the status of EC-related majors in domestic and oversea universities, combined with EC professional training experiences at the undergraduate level in Jiangxi Normal University, this paper proposes the guideline, objective and characteristic of the training mode on the Informationalization-based business compound professionals, with the example of EC major. Furthermore, a systematic tentative research is made on the training way of information and innovation ability, integration between IT and curricula, curricula design, practice and practice-simulation teaching, integration between vocational education program and degree education program. This paper proposes the new training mode on the Informationalization-based business compound professionals firstly in China and has some implications both to the theory and practice of Informationalization-based business compound professionals training in universities of China.