Severe chronic idiopathic suppurative lymphoplasmacytic rhinitis in a dog

A 5-year-old, intact male, Border collie dog was evaluated because of a 10-day history of right epistaxis. On physical examination, there was no evidence of nasal discharge. A mild depigmentation of the right nasal planum was observed. The infectious panel was negative for Leishmania i., Dirofilaria i. , A. vasorum and tickborne infectious diseases. CT scan of the head, rhinoscopy, histopathologic examination of the right nasal mucosa, fungal culture and PCR sequencing were performed at initial diagnostic workup and follow-up. A severe and diffuse chronic idiopathic suppurative lymphoplasmacytic rhinitis was diagnosed, along with isolation of Trichosporon ashaii . Because of the unsatisfactory clinical response to marbofloxacin, piroxicam, itraconazole and clotrimazole, oral prednisone was administered. After the initial 2 weeks, prednisone was progressively reduced and discontinued 9 months later. The dog showed complete disappearance of clinical signs, without recurrence after therapy discontinuation.

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