Organophotocatalysed synthesis of 2-piperidinones in one step via [1 + 2 + 3] strategy

[1]  L. Naesens,et al.  A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro , 2022, Pharmaceuticals.

[2]  F. Glorius,et al.  Merging Carbonyl Addition with Photocatalysis. , 2022, Accounts of chemical research.

[3]  W. Shu,et al.  Organophotocatalytic Regioselective C-H Alkylation of Electron-Rich Arenes Using Activated and Unactivated Alkenes. , 2022, Angewandte Chemie.

[4]  Liang Chang,et al.  Alkoxy Radicals See the Light: New Paradigms of Photochemical Synthesis. , 2021, Chemical reviews.

[5]  David A. Nicewicz,et al.  Photoredox-Catalyzed C-H Functionalization Reactions. , 2021, Chemical reviews.

[6]  Davide Ravelli,et al.  Direct Photocatalyzed Hydrogen Atom Transfer (HAT) for Aliphatic C–H Bonds Elaboration , 2021, Chemical reviews.

[7]  D. Nocera,et al.  Mechanistic Investigation and Optimization of Photoredox Anti-Markovnikov Hydroamination. , 2021, Journal of the American Chemical Society.

[8]  Shaopeng Li,et al.  Production of Piperidine and δ-Lactam Chemicals from Biomass-Derived Triacetic Acid Lactone. , 2021, Angewandte Chemie.

[9]  W. Shu,et al.  Direct Access to Primary Amines from Alkenes via Selective Metal-Free Hydroamination. , 2021, Angewandte Chemie.

[10]  F. Glorius,et al.  Interrupted Pyridine Hydrogenation: Asymmetric Synthesis of δ‐Lactams , 2021, Angewandte Chemie.

[11]  Philip R. D. Murray,et al.  Photocatalytic Generation of Aminium Radical Cations for C─N Bond Formation. , 2020, ACS catalysis.

[12]  David A. Nicewicz,et al.  Direct Synthesis of Bicyclic Acetals via Visible Light Catalysis , 2020, iScience.

[13]  A. Studer,et al.  Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition , 2019, Angewandte Chemie.

[14]  David C. Miller,et al.  Anti-Markovnikov Hydroamination of Unactivated Alkenes with Primary Alkyl Amines. , 2019, Journal of the American Chemical Society.

[15]  David A. Nicewicz,et al.  Anti-Markovnikov Hydroazidation of Activated Olefins via Organic Photoredox Catalysis , 2019, Synlett.

[16]  Matthew Burns,et al.  Asymmetric δ-Lactam Synthesis with a Monomeric Streptavidin Artificial Metalloenzyme. , 2019, Journal of the American Chemical Society.

[17]  T. Yoon,et al.  Tandem copper and photoredox catalysis in photocatalytic alkene difunctionalization reactions , 2019, Beilstein journal of organic chemistry.

[18]  C. Doyle,et al.  An Efficient Two-Step Preparation of α-, β-, γ- or δ-Amino Acids from 2-Pyrazinones, 2-Hydroxypyrimidines or 2-Pyridones Respectively , 2018, European Journal of Organic Chemistry.

[19]  F. Sarabia,et al.  Cyclopentene Annulations of Alkene Radical Cations with Vinyl Diazo Species Using Photocatalysis. , 2018, Angewandte Chemie.

[20]  Joshua B. McManus,et al.  Generation and Alkylation of α-Carbamyl Radicals via Organic Photoredox Catalysis. , 2018, Journal of the American Chemical Society.

[21]  Shouyun Yu,et al.  Photoredox-Catalyzed Radical Relay Reaction Toward Functionalized Vicinal Diamines , 2018, Synthesis.

[22]  David A. Nicewicz,et al.  Direct Synthesis of Polysubstituted Aldehydes via Visible-Light Catalysis. , 2018, Angewandte Chemie.

[23]  Shouyun Yu,et al.  Photoredox-Induced Radical Relay toward Functionalized β-Amino Alcohol Derivatives. , 2018, Organic letters.

[24]  David A. Nicewicz,et al.  Visible-Light-Mediated [4+2] Cycloaddition of Styrenes: Synthesis of Tetralin Derivatives. , 2017, Angewandte Chemie.

[25]  Xin Zhang,et al.  Catalytic intermolecular hydroaminations of unactivated olefins with secondary alkyl amines , 2017, Science.

[26]  David A. Nicewicz,et al.  Reversing the Regioselectivity of Halofunctionalization Reactions through Cooperative Photoredox and Copper Catalysis. , 2017, Angewandte Chemie.

[27]  C. Schneider,et al.  The Brønsted Acid-Catalyzed, Enantioselective Aza-Diels-Alder Reaction for the Direct Synthesis of Chiral Piperidones. , 2017, Chemistry.

[28]  David A. Nicewicz,et al.  A General Approach to Catalytic Alkene Anti-Markovnikov Hydrofunctionalization Reactions via Acridinium Photoredox Catalysis. , 2016, Accounts of chemical research.

[29]  N. Mizuno,et al.  Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides. , 2016, Angewandte Chemie.

[30]  Bin Rao,et al.  Highly Selective Hydrogenation of Aromatic Ketones and Phenols Enabled by Cyclic (Amino)(alkyl)carbene Rhodium Complexes. , 2015, Journal of the American Chemical Society.

[31]  F. Glorius,et al.  Asymmetric Homogeneous Hydrogenation of 2-Pyridones , 2015, Synlett.

[32]  J. T. Njardarson,et al.  Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals. , 2014, Journal of medicinal chemistry.

[33]  David A. Nicewicz,et al.  Butyrolactone synthesis via polar radical crossover cycloaddition reactions: diastereoselective syntheses of methylenolactocin and protolichesterinic acid. , 2014, Organic letters.

[34]  David A. Nicewicz,et al.  The direct anti-Markovnikov addition of mineral acids to styrenes. , 2014, Nature chemistry.

[35]  David A. Nicewicz,et al.  anti-Markovnikov hydroamination of alkenes catalyzed by a two-component organic photoredox system: direct access to phenethylamine derivatives. , 2014, Angewandte Chemie.

[36]  Yehoshoa Ben‐David,et al.  Oxidant-free conversion of cyclic amines to lactams and H2 using water as the oxygen atom source. , 2014, Journal of the American Chemical Society.

[37]  Richard D. Taylor,et al.  Rings in drugs. , 2014, Journal of medicinal chemistry.

[38]  Ying He,et al.  One-pot synthesis of optically enriched 2-piperidinones from aliphatic aldehydes and cyanoacrylamides. , 2013, Organic letters.

[39]  David A. Nicewicz,et al.  Direct catalytic anti-Markovnikov addition of carboxylic acids to alkenes. , 2013, Journal of the American Chemical Society.

[40]  T. Rovis,et al.  Asymmetric N-heterocyclic carbene catalyzed addition of enals to nitroalkenes: controlling stereochemistry via the homoenolate reactivity pathway to access δ-lactams. , 2013, Journal of the American Chemical Society.

[41]  Y. Liu,et al.  Regiospecific 6-endo-annulation of in situ generated 3,4-dienamides/acids: synthesis of δ-lactams and δ-lactones. , 2013, Organic letters.

[42]  David A. Nicewicz,et al.  Synthesis of highly substituted tetrahydrofurans by catalytic polar-radical-crossover cycloadditions of alkenes and alkenols. , 2013, Angewandte Chemie.

[43]  J. Medina,et al.  An expeditious synthesis of the MDM2-p53 inhibitor AM-8553. , 2012, Journal of the American Chemical Society.

[44]  I. Císařová,et al.  Highly enantioselective organocatalytic synthesis of piperidines. Formal synthesis of (-)-Paroxetine , 2009 .

[45]  Y. Landais,et al.  Multicomponent radical processes: synthesis of substituted piperidinones. , 2007, Journal of the American Chemical Society.

[46]  C. Escolano,et al.  Chiral oxazolopiperidone lactams: versatile intermediates for the enantioselective synthesis of piperidine-containing natural products. , 2006, Chemistry.

[47]  B. Jones,et al.  Structure-activity relationships of 1-alkyl-5-(3,4-dichlorophenyl)- 5-[2-[(3-substituted)-1-azetidinyl]ethyl]-2-piperidones. 1. Selective antagonists of the neurokinin-2 receptor. , 2002, Journal of medicinal chemistry.

[48]  T. Honda,et al.  Concise enantiospecific synthesis of a coccinellied alkaloid, (-)-adalinine. , 2000, Organic letters.

[49]  H. Alper,et al.  Regioselective synthesis of piperidinones by metal-catalyzed ring expansion-carbonylation reactions. Remarkable cobalt and/or ruthenium carbonyl catalyzed rearrangement and cyclization reactions , 1992 .

[50]  H. Sakuragi,et al.  ELECTROCHEMICAL OXIDATION OF AROMATIC OLEFINS. DEPENDENCE OF THE REACTION COURSE ON THE STRUCTURE OF THE OLEFINS AND ON THE NATURE OF THE ANODES , 1981 .

[51]  B. Belleau,et al.  Electrochemical methoxylation of vinyl ethers: a novel anodic dimerization reaction , 1969 .

[52]  Pengfei Li,et al.  One-Step Access to Primary Amines from Alkenes and Ammonium Carbonate by One-Step Metal-Free Catalysis , 2021, Chinese Journal of Organic Chemistry.

[53]  D. O'Hagan.  Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids (1998 to 1999) , 2000 .