Inner speech models of auditory verbal hallucinations: Evidence from behavioural and neuroimaging studies

A range of psychological theories have been proposed to account for the experience of auditory hallucinations in patients with psychosis. Influential amongst these theories are those implicating the defective monitoring of inner speech. Furthermore, self-monitoring and inner speech models have been the most studied using functional imaging. The aim of this article is to review the behavioural and neuroimaging evidence for the impaired monitoring of inner speech in patients who experience auditory verbal hallucinations. A comprehensive literature search was conducted for research investigating inner speech and cognitive self-monitoring models of auditory hallucinations in patients with schizophrenia. The evidence is critically discussed and directions for future investigations are suggested.

[1]  C. Carter,et al.  The anterior cingulate as a conflict monitor: fMRI and ERP studies , 2002, Physiology & Behavior.

[2]  G. Dunn,et al.  Reasoning, emotions, and delusional conviction in psychosis. , 2005, Journal of abnormal psychology.

[3]  Paul Allen,et al.  Neural correlates of the misattribution of speech in schizophrenia , 2007, British Journal of Psychiatry.

[4]  I Feinberg,et al.  Efference copy and corollary discharge: implications for thinking and its disorders. , 1978, Schizophrenia bulletin.

[5]  D Hemsley,et al.  Verbal self-monitoring and auditory verbal hallucinations in patients with schizophrenia , 2001, Psychological Medicine.

[6]  Peter B. Jones,et al.  Spatial and temporal mapping of neural activity associated with auditory hallucinations , 1999, The Lancet.

[7]  C. Frith,et al.  Experiences of alien control in schizophrenia reflect a disorder in the central monitoring of action , 1989, Psychological Medicine.

[8]  P. McGuire,et al.  Impaired verbal self-monitoring in psychosis: effects of state, trait and diagnosis , 2006, Psychological Medicine.

[9]  C. Ray Chronic fatigue syndrome and depression: conceptual and methodological ambiguities , 1991, Psychological Medicine.

[10]  P. McGuire,et al.  An fMRI study of verbal self-monitoring: neural correlates of auditory verbal feedback. , 2006, Cerebral cortex.

[11]  S. Wessely,et al.  Reasoning in Deluded Schizophrenic and Paranoid Patients: Biases in Performance on a Probabilistic Inference Task , 1991, The Journal of nervous and mental disease.

[12]  P. McGuire,et al.  Misattribution of external speech in patients with hallucinations and delusions , 2004, Schizophrenia Research.

[13]  Peter G. Morris,et al.  The functional anatomy of auditory hallucinations in schizophrenia , 2000, Psychiatry Research: Neuroimaging.

[14]  M. Corbetta,et al.  Selective and divided attention during visual discriminations of shape, color, and speed: functional anatomy by positron emission tomography , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[15]  C Nahmias,et al.  Where the imaginal appears real: a positron emission tomography study of auditory hallucinations. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[16]  S. Blakemore,et al.  The perception of self-produced sensory stimuli in patients with auditory hallucinations and passivity experiences: evidence for a breakdown in self-monitoring , 2000, Psychological Medicine.

[17]  C. Cahill Psychotic experiences induced in deluded patients using distorted auditory feedback. , 1996, Cognitive neuropsychiatry.

[18]  Michael J Brammer,et al.  Engagement of brain areas implicated in processing inner speech in people with auditory hallucinations. , 2003, The British journal of psychiatry : the journal of mental science.

[19]  Judith M Ford,et al.  Corollary discharge dysfunction in schizophrenia: can it explain auditory hallucinations? , 2005, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[20]  C. Büchel,et al.  Neuroanatomy of "hearing voices": a frontotemporal brain structural abnormality associated with auditory hallucinations in schizophrenia. , 2004, Cerebral cortex.

[21]  T. Ditman,et al.  A Source‐Monitoring Account of Auditory Verbal Hallucinations in Patients with Schizophrenia , 2005, Harvard review of psychiatry.

[22]  G. Dunn,et al.  Delusions and decision-making style: use of the Need for Closure Scale. , 2006, Behaviour research and therapy.

[23]  P. McGuire,et al.  Misattribution of self-generated speech in relation to hallucinatory proneness and delusional ideation in healthy volunteers , 2006, Schizophrenia Research.

[24]  Elia Formisano,et al.  The functional neuroanatomy of metrical stress evaluation of perceived and imagined spoken words. , 2004, Cerebral cortex.

[25]  Judith M Ford,et al.  Electrophysiological evidence of corollary discharge dysfunction in schizophrenia during talking and thinking. , 2004, Journal of psychiatric research.

[26]  R. M. Murray,et al.  Functional anatomy of inner speech and auditory verbal imagery , 1995, Schizophrenia Research.

[27]  A. Aleman,et al.  Compelling imagery, unanticipated speech and deceptive memory: Neurocognitive models of auditory verbal hallucinations in schizophrenia , 2004, Cognitive neuropsychiatry.

[28]  Paul D. Ellsworth,et al.  Diagnostic and Statistical Manual of Mental Disorder , 1980 .

[29]  W. Levelt,et al.  Monitoring and self-repair in speech , 1983, Cognition.

[30]  C Frith,et al.  Brain mechanisms associated with top-down processes in perception. , 1997, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[31]  K. Hugdahl,et al.  MR MORPHOMETRY ANALYSIS OF GREY MATTER VOLUME REDUCTION IN SCHIZOPHRENIA: ASSOCIATION WITH HALLUCINATIONS , 2006, The International journal of neuroscience.

[32]  Michael I. Jordan,et al.  Are arm trajectories planned in kinematic or dynamic coordinates? An adaptation study , 1995, Experimental Brain Research.

[33]  Paul Allen,et al.  Misattribution of speech and impaired connectivity in patients with auditory verbal hallucinations , 2007, Human brain mapping.

[34]  Mario Beauregard,et al.  Cerebral activity associated with auditory verbal hallucinations: a functional magnetic resonance imaging case study. , 2002, Journal of psychiatry & neuroscience : JPN.

[35]  Philip K McGuire,et al.  Verbal self-monitoring and auditory hallucinations in schizophrenia , 1999, The Lancet.

[36]  Derek K. Jones,et al.  A diffusion tensor imaging study of fasciculi in schizophrenia. , 2007, The American journal of psychiatry.

[37]  C. D. Frith,et al.  Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations , 1995, The Lancet.

[38]  Richard S. J. Frackowiak,et al.  A functional neuroanatomy of hallucinations in schizophrenia , 1995, Nature.

[39]  J. McGrath,et al.  The cognitive neuropsychology of schizophrenia. , 1997 .

[40]  Charles F Stevens,et al.  Synaptic plasticity , 1998, Current Biology.

[41]  P. Mu¨ller-Preuss,et al.  Inhibition of auditory cortical neurons during phonation , 1981, Brain Research.

[42]  R. Murray,et al.  Functional anatomy of auditory verbal imagery in schizophrenic patients with auditory hallucinations. , 2000, The American journal of psychiatry.

[43]  J van Os,et al.  The continuity of psychotic experiences in the general population. , 2001, Clinical psychology review.

[44]  M. Jeannerod,et al.  Looking for the agent: an investigation into consciousness of action and self-consciousness in schizophrenic patients , 1997, Cognition.

[45]  R. Coppola,et al.  Unnatural practices, unspeakable actions: a study of delayed auditory feedback in schizophrenia. , 1997, The American journal of psychiatry.

[46]  R. Passingham,et al.  SUPPLEMENTARY MOTOR CORTEX AND SELF-INITIATED MOVEMENT , 1989 .

[47]  S. Hollis,et al.  Syndromes of schizophrenia on factor analysis , 1992, British Journal of Psychiatry.

[48]  R. Murray,et al.  Increased blood flow in Broca's area during auditory hallucinations in schizophrenia , 1993, The Lancet.

[49]  E. Stern,et al.  Towards a functional neuroanatomy of conscious perception and its modulation by volition: implications of human auditory neuroimaging studies. , 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[50]  M. Kurachi,et al.  Left superior temporal blood flow increases in schizophrenic and schizophreniform patients with auditory hallucination: A longitudinal case study using123I-IMP SPECT , 2005, European Archives of Psychiatry and Clinical Neuroscience.

[51]  I. Hickie,et al.  Propofol and ECT , 1992, British Journal of Psychiatry.

[52]  R. Murray,et al.  Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. , 2000, Archives of general psychiatry.

[53]  A. David The cognitive neuropsychiatry of auditory verbal hallucinations: an overview. , 2004, Cognitive neuropsychiatry.

[54]  P. McGuire,et al.  Verbal self-monitoring in psychosis: a non-replication , 2007, Psychological Medicine.

[55]  D. Hubl,et al.  Pathways that make voices: white matter changes in auditory hallucinations. , 2004, Archives of general psychiatry.

[56]  C. Frith,et al.  Towards a Neuropsychology of Schizophrenia , 1988, British Journal of Psychiatry.

[57]  W. Singer,et al.  Activation of Heschl’s Gyrus during Auditory Hallucinations , 1999, Neuron.

[58]  R. Malenka Mucking up movements , 1994, Nature.

[59]  F. Bermpohl,et al.  Cortical midline structures and the self , 2004, Trends in Cognitive Sciences.