Spatial Distribution of Responses to Simple and Complex Sounds in the Primary Auditory Cortex

The basic functional organization of the cat primary auditory cortex is discussed as it is revealed by electrophysiological studies of the distribution of elementary receptive field (RF) parameters. RFs of cortical neurons have been shown to vary considerably from neuron to neuron; additionally, specific RF properties vary independently. Furthermore, some of the RF properties are nonhomogeneously distributed across the auditory cortex and can be interpreted as forming ‘maps’ that represent specific stimulus information in a topographic way. Accordingly, the functional organization of the primary auditory cortex is interpreted as a series of superimposed independent parameter maps. The consequences of such a layout for the spatial and temporal coding of pure tones and speech sounds is illustrated and ramifications for the interpretation of far-field event-related potentials are discussed.

[1]  J. Rauschecker,et al.  Processing of complex sounds in the macaque nonprimary auditory cortex. , 1995, Science.

[2]  E. R. Flynn,et al.  Factors which affect spatial resolving power in large array biomagnetic sensors , 1994 .

[3]  Ikuo Taniguchi,et al.  The columnar and layer-specific response properties of neurons in the primary auditory cortex of Mongolian gerbils , 1997, Hearing Research.

[4]  M M Merzenich,et al.  Representation of a species-specific vocalization in the primary auditory cortex of the common marmoset: temporal and spectral characteristics. , 1995, Journal of neurophysiology.

[5]  H. Vaughan,et al.  Tonotopic features of speech-evoked activity in primate auditory cortex , 1990, Brain Research.

[6]  D. Irvine,et al.  Sensitivity of neurons in cat primary auditory cortex to tones and frequency-modulated stimuli. II: Organization of response properties along the ‘isofrequency’ dimension , 1992, Hearing Research.

[7]  C. Schreiner,et al.  Physiology and topography of neurons with multipeaked tuning curves in cat primary auditory cortex. , 1991, Journal of neurophysiology.

[8]  J. C. Middlebrooks,et al.  Binaural response-specific bands in primary auditory cortex (AI) of the cat: Topographical organization orthogonal to isofrequency contours , 1980, Brain Research.

[9]  M. Merzenich,et al.  Frequency representation in auditory cortex of the common marmoset (Callithrix jacchus jacchus) , 1986, The Journal of comparative neurology.

[10]  O Bertrand,et al.  Evidence for a tonotopic organization of the auditory cortex observed with auditory evoked potentials. , 1991, Acta oto-laryngologica. Supplementum.

[11]  L. Aitkin,et al.  Azimuthal sensitivity of neurons in primary auditory cortex of cats. II. Organization along frequency-band strips. , 1990, Journal of neurophysiology.

[12]  C E Schreiner,et al.  Basic functional organization of second auditory cortical field (AII) of the cat. , 1984, Journal of neurophysiology.

[13]  P. Knight,et al.  Representation of the cochlea within the anterior auditory field (AAF) of the cat , 1977, Brain Research.

[14]  T. Imig,et al.  Binaural columns in the primary field (A1) of cat auditory cortex , 1977, Brain Research.

[15]  T. Imig,et al.  Functional organization of sound direction and sound pressure level in primary auditory cortex of the cat. , 1994, Journal of neurophysiology.

[16]  M. Merzenich,et al.  Responses of neurons in auditory cortex of the macaque monkey to monaural and binaural stimulation. , 1973, Journal of neurophysiology.

[17]  Mitchell Steinschneider,et al.  Speech evoked activity in the auditory radiations and cortex of the awake monkey , 1982, Brain Research.

[18]  C E Schreiner,et al.  Functional topographies in the primary auditory cortex of the cat. , 1991, Acta oto-laryngologica. Supplementum.

[19]  R. Reale,et al.  Tonotopic organization in auditory cortex of the cat , 1980, The Journal of comparative neurology.

[20]  C. Schreiner,et al.  Representation of amplitude modulation in the auditory cortex of the cat. I. The anterior auditory field (AAF) , 1986, Hearing Research.

[21]  M M Merzenich,et al.  Representation of cochlea within primary auditory cortex in the cat. , 1975, Journal of neurophysiology.

[22]  Richard J Weinberg,et al.  Are Topographic Maps Fundamental to Sensory Processing? , 1997, Brain Research Bulletin.

[23]  M Hoke,et al.  Tonotopic organization of the auditory cortex: pitch versus frequency representation. , 1989, Science.

[24]  C E Schreiner,et al.  Neuronal responses in cat primary auditory cortex to electrical cochlear stimulation. I. Intensity dependence of firing rate and response latency. , 1994, Journal of neurophysiology.

[25]  P. Heil,et al.  Auditory cortical onset responses revisited. I. First-spike timing. , 1997, Journal of neurophysiology.

[26]  Temporal Encoding of Phonetic Features in Auditory Cortex a , 1993, Annals of the New York Academy of Sciences.

[27]  C E Schreiner,et al.  Topography of intensity tuning in cat primary auditory cortex: single-neuron versus multiple-neuron recordings. , 1995, Journal of neurophysiology.

[28]  Christoph E. Schreiner,et al.  Mammalian Auditory Cortex—Some Comparative Observations , 1992 .

[29]  Z. Wollberg,et al.  DISCRIMINATION OF COMMUNICATION CALLS IN THE SQUIRREL MONKEY: "CALL DETECTORS" OR "CELL ENSEMBLES"? , 1991, Journal of basic and clinical physiology and pharmacology.

[30]  L. Aitkin,et al.  Azimuthal sensitivity of neurons in primary auditory cortex of cats. I. Types of sensitivity and the effects of variations in stimulus parameters. , 1990, Journal of neurophysiology.

[31]  R. Ilmoniemi,et al.  Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain , 1993 .

[32]  S. Shamma,et al.  Organization of response areas in ferret primary auditory cortex. , 1993, Journal of neurophysiology.

[33]  T. Imig,et al.  Single-unit selectivity to azimuthal direction and sound pressure level of noise bursts in cat high-frequency primary auditory cortex. , 1990, Journal of neurophysiology.

[34]  D. P. Phillips,et al.  Intracortical connections and their physiological correlates in the primary auditory cortex (AI) of the cat , 1988, The Journal of comparative neurology.

[35]  C. Gross,et al.  Neural ensemble coding in inferior temporal cortex. , 1994, Journal of neurophysiology.

[36]  M. L. Sutter,et al.  Functional topography of cat primary auditory cortex: response latencies , 1997, Journal of Comparative Physiology A.

[37]  Cortical responses to changes in auditory stimuli. Magnetoencephalographic studies. , 1991, Acta oto-laryngologica. Supplementum.

[38]  Nathaniel T. McMullen,et al.  Thalamocortical patches in auditory neocortex , 1993, Brain Research.

[39]  Peter Heil,et al.  Topographic representation of tone intensity along the isofrequency axis of cat primary auditory cortex , 1994, Hearing Research.

[40]  Jon H Kaas,et al.  Topographic Maps are Fundamental to Sensory Processing , 1997, Brain Research Bulletin.

[41]  C E Schreiner,et al.  Functional topography of cat primary auditory cortex: distribution of integrated excitation. , 1990, Journal of neurophysiology.

[42]  Leslie G. Ungerleider.  Two cortical visual systems , 1982 .

[43]  M. Mishkin,et al.  Serial and parallel processing in rhesus monkey auditory cortex , 1997, The Journal of comparative neurology.

[44]  J. T. Massey,et al.  Mental rotation of the neuronal population vector. , 1989, Science.

[45]  Christoph E Schreiner,et al.  Order and disorder in auditory cortical maps , 1995, Current Opinion in Neurobiology.

[46]  C E Schreiner,et al.  Topography of excitatory bandwidth in cat primary auditory cortex: single-neuron versus multiple-neuron recordings. , 1992, Journal of neurophysiology.

[47]  D. Irvine,et al.  Sensitivity of neurons in cat primary auditory cortex to tones and frequency-modulated stimuli. I: Effects of variation of stimulus parameters , 1992, Hearing Research.