Overview of the quality standard research of traditional Chinese medicine

Traditional Chinese medicine (TCM) has been widely used for the prevention and treatment of various diseases for a long time in China. Due to its proven efficacy, wide applications, and low side effect, TCM has increasingly attracted worldwide attention. However, one of the biggest challenges facing the clinical practice of TCM is the uncontrollable quality. In this review, the progress of the development and the current status of quality standard as well as new quality control techniques introduced in Chinese Pharmacopoeia (2010 edition), such as liquid chromatography hyphenated mass spectrometry (LC-MS), fingerprint, quantitative analysis of multicomponents by single-marker (QAMS), thin layer chromatography bio-autographic assay (TLC-BAA), and DNA molecular marker technique, are briefly overviewed.

[1]  W. Oleszek,et al.  Chromatographic determination of plant saponins--an update (2002-2005). , 2006, Journal of chromatography. A.

[2]  J Zhao,et al.  Strategies for quality control of Chinese medicines. , 2011, Journal of pharmaceutical and biomedical analysis.

[3]  C. Poole.  Thin-layer chromatography: challenges and opportunities. , 2003, Journal of chromatography. A.

[4]  Jing Zhao,et al.  CEC of phytochemical bioactive compounds , 2010, Electrophoresis.

[5]  M. Ganzera,et al.  Recent advances on HPLC/MS in medicinal plant analysis. , 2011, Journal of pharmaceutical and biomedical analysis.

[6]  P. Drasar,et al.  Recent advances in analysis of Chinese medical plants and traditional medicines. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[7]  Bruno David,et al.  Recent analytical approaches in quality control of traditional Chinese medicines--a review. , 2010, Analytica chimica acta.

[8]  A Marston,et al.  A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants. , 2002, Phytochemical analysis : PCA.

[9]  E. de Rijke,et al.  Analytical separation and detection methods for flavonoids. , 2006, Journal of chromatography. A.

[10]  N. Mimica-Dukić,et al.  Antimicrobial and Antioxidant Activities of Three Mentha Species Essential Oils , 2003, Planta medica.

[11]  Shilin Chen,et al.  [DNA barcoding the medicinal plants of the genus Paris]. , 2010, Yao xue xue bao = Acta pharmaceutica Sinica.

[12]  C. Cespedes,et al.  Antioxidant and insect growth regulatory activities of stilbenes and extracts from Yucca periculosa. , 2003, Phytochemistry.

[13]  Fan Pei-hong.  Application of TLC-bioautography to drug screening , 2005 .

[14]  Jeffrey C Moore,et al.  Antioxidant phenolic compounds from walnut kernels (Juglans regia L.) , 2009 .

[15]  A. Fernandez-Gutiérrez,et al.  Application and potential of capillary electroseparation methods to determine antioxidant phenolic compounds from plant food material. , 2010, Journal of pharmaceutical and biomedical analysis.

[16]  Padmavati Manchikanti,et al.  Herbal drugs: standards and regulation. , 2010, Fitoterapia.

[17]  R. Bauer,et al.  Are national quality standards for traditional Chinese herbal medicine sufficient? Current governmental regulations for traditional Chinese herbal medicine in certain Western countries and China as the Eastern origin country. , 2005, Complementary therapies in medicine.

[18]  A L Homans,et al.  Direct bioautography on thin-layer chromatograms as a method for detecting fungitoxic substances. , 1970, Journal of chromatography.

[19]  D. Nagle,et al.  A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens. , 2000, Journal of natural products.

[20]  K. Ingkaninan,et al.  Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. , 2001, Journal of chromatography. A.

[21]  U. Brinkman,et al.  Recent developments in the application of comprehensive two-dimensional gas chromatography. , 2008, Journal of chromatography. A.

[22]  Min Yang,et al.  Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. , 2009, Journal of chromatography. A.

[23]  Lian‐Wen Qi,et al.  Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry. , 2009, Journal of chromatography. A.

[24]  R. Gutiérrez,et al.  High-performance thin-layer chromatography-bioautography for multiple antibiotic residues in cow's milk. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[25]  Pei-Shan Xie,et al.  Understanding the traditional aspect of Chinese medicine in order to achieve meaningful quality control of Chinese materia medica. , 2009, Journal of chromatography. A.

[26]  Tao Wu,et al.  TLC bioautography-guided isolation of antioxidants from fruit of Perilla frutescens var. acuta , 2009 .

[27]  G. Chou,et al.  [Evaluation of antioxidant activity of Radix Linderae and other two Chinese drugs using TLC-bioautography]. , 2006, Yao xue xue bao = Acta pharmaceutica Sinica.

[28]  Gang Chen,et al.  Determination of bioactive constituents in traditional Chinese medicines by CE with electrochemical detection. , 2006, Current medicinal chemistry.

[29]  Xinmiao Liang,et al.  Qualitative and quantitative analysis in quality control of traditional Chinese medicines. , 2009, Journal of chromatography. A.

[30]  Zhou Li-gang.  Detection of Antimicrobial Components from Extracts of the Endophytic Fungi Associated with Paris polyphylla var.yunnanensis Using TLC-Bioautography-MTT Assay , 2008 .

[31]  Jian-Guo Jiang,et al.  Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine , 2009, British journal of pharmacology.

[32]  Liang Chen,et al.  Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. , 2010, Journal of chromatography. A.

[33]  S. Zhao,et al.  Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials , 2009, Chinese medicine.

[34]  M. Ganzera,et al.  Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications , 2008, Electrophoresis.

[35]  Y. Gupta,et al.  Therapeutic potential of herbal drugs in cerebral ischemia. , 2010, Indian journal of physiology and pharmacology.

[36]  G. Smythe,et al.  Extraction and chromatography-mass spectrometric analysis of the active principles from selected Chinese herbs and other medicinal plants. , 2003, The American journal of Chinese medicine.

[37]  A. Marston.  Role of advances in chromatographic techniques in phytochemistry. , 2007, Phytochemistry.