Long‐term survival following elective colon cancer surgery in the aged. A population‐based cohort study

The number of colorectal cancer patients increases with age. Long‐term data support personalized management due to heterogeneity within the older population. This registry‐ and population‐based study aimed to analyse long‐term survival, and causes of death, after elective colon cancer surgery in the aged, focusing on patients who survived more than 3 months postoperatively.

[1]  H. Huhtala,et al.  Risk factors of short-term survival in the aged in elective colon cancer surgery: a population-based study , 2019, International Journal of Colorectal Disease.

[2]  T. H. Nguyen,et al.  The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 , 2019, The lancet. Gastroenterology & hepatology.

[3]  I. Miyashiro,et al.  Effect of adjuvant chemotherapy on survival benefit in stage III colon cancer patients stratified by age: a Japanese real-world cohort study , 2019, BMC Cancer.

[4]  A. Ballestrero,et al.  Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status. , 2019, Journal of geriatric oncology.

[5]  V. Lemmens,et al.  Postoperative mortality in elderly patients with colorectal cancer: The impact of age, time-trends and competing risks of dying. , 2019, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[6]  P. Halonen,et al.  Chronic conditions and multimorbidity in population aged 90 years and over: associations with mortality and long-term care admission. , 2019, Age and ageing.

[7]  H. Maas,et al.  The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer - A longitudinal follow-up study. , 2019, Journal of geriatric oncology.

[8]  H. Baba,et al.  Frailty predicts severe postoperative complications after elective colorectal surgery. , 2019, American journal of surgery.

[9]  G. D. de Bock,et al.  Long-Term Survival in Octogenarians After Surgical Treatment for Colorectal Cancer: Prevention of Postoperative Complications is Key , 2018, Annals of Surgical Oncology.

[10]  B. Glimelius,et al.  Recurrence Risk After Up-to-Date Colon Cancer Staging, Surgery, and Pathology: Analysis of the Entire Swedish Population , 2018, Diseases of the colon and rectum.

[11]  N. Ventham,et al.  Colorectal cancer outcomes in nonagenarian patients: A case series. , 2018, International journal of surgery.

[12]  A. Carrato,et al.  Efficacy of adjuvant chemotherapy for elderly patients with colon cancer. , 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

[13]  U. Gunnarsson,et al.  The older patient's experience of the healthcare chain and information when undergoing colorectal cancer surgery according to the enhanced recovery after surgery concept , 2018, Journal of clinical nursing.

[14]  J. Huh,et al.  Oncologic outcome of colorectal cancer patients over age 80: a propensity score-matched analysis , 2018, International Journal of Colorectal Disease.

[15]  T. Nagayasu,et al.  The Charlson Comorbidity Index as an Independent Prognostic Factor in Older Colorectal Cancer Patients , 2018, Indian Journal of Surgery.

[16]  H. Wildiers,et al.  Postoperative complications in individuals aged 70 and over undergoing elective surgery for colorectal cancer , 2017, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[17]  V. Celentano,et al.  Colorectal cancer surgery in the very elderly patient: a systematic review of laparoscopic versus open colorectal resection , 2017, International Journal of Colorectal Disease.

[18]  U. Settmacher,et al.  Surgery for colorectal cancer in elderly patients: how can we improve outcome? , 2017, Journal of Cancer Research and Clinical Oncology.

[19]  K. Matzel,et al.  Prognosis of patients with colonic carcinoma before, during and after implementation of complete mesocolic excision , 2016, The British journal of surgery.

[20]  Chun-Ming Chang,et al.  Correction: Adjusted Age-Adjusted Charlson Comorbidity Index Score as a Risk Measure of Perioperative Mortality before Cancer Surgery , 2016, PloS one.

[21]  J. Monson,et al.  The impact of age on complications, survival, and cause of death following colon cancer surgery , 2016, British Journal of Cancer.

[22]  T. Arulampalam,et al.  What happens when we do not operate? Survival following conservative bowel cancer management. , 2016, Annals of the Royal College of Surgeons of England.

[23]  L. Boni,et al.  Is laparoscopic surgery really effective for the treatment of colon and rectal cancer in very elderly over 80 years old? A prospective multicentric case–control assessment , 2016, Surgical Endoscopy.

[24]  Chun-Ming Chang,et al.  Adjusted Age-Adjusted Charlson Comorbidity Index Score as a Risk Measure of Perioperative Mortality before Cancer Surgery , 2016, PloS one.

[25]  H. Brenner,et al.  On-going improvement and persistent differences in the survival for patients with colon and rectum cancer across Europe 1999-2007 - Results from the EUROCARE-5 study. , 2015, European journal of cancer.

[26]  D. Sargent,et al.  Treatment of colorectal cancer in older patients: International Society of Geriatric Oncology (SIOG) consensus recommendations 2013. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

[27]  J. E. Jansen,et al.  Disease-free survival after complete mesocolic excision compared with conventional colon cancer surgery: a retrospective, population-based study. , 2015, The Lancet. Oncology.

[28]  R. Audisio,et al.  Survival outcome of operated and non-operated elderly patients with rectal cancer: A Surveillance, Epidemiology, and End Results analysis. , 2014, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[29]  P. Walsh,et al.  Determinants of short- and long-term survival from colorectal cancer in very elderly patients. , 2014, Journal of geriatric oncology.

[30]  F. Landi,et al.  Laparoscopy-assisted versus open colectomy for treatment of colon cancer in the elderly: morbidity and mortality outcomes in 545 patients , 2014, Surgical Endoscopy.

[31]  Vinh Q Nguyen,et al.  Colorectal Cancer Resections in the Aging US Population: A Trend Toward Decreasing Rates and Improved Outcomes. , 2014, JAMA surgery.

[32]  D. Jayne,et al.  The Impact of Postoperative Complications on Long-term Quality of Life After Curative Colorectal Cancer Surgery , 2014, Annals of surgery.

[33]  C. Greenberg,et al.  Surgical treatment of colon cancer in patients aged 80 years and older , 2013, Cancer.

[34]  K. Tan,et al.  Long-Term Outcome Following Surgery for Colorectal Cancers in Octogenarians: A Single Institution’s Experience of 204 Patients , 2012, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.

[35]  N. Demartines,et al.  Classification of Surgical Complications: A New Proposal With Evaluation in a Cohort of 6336 Patients and Results of a Survey , 2004, Annals of Surgery.

[36]  A Penttilä,et al.  The validity of death certificates: routine validation of death certification and its effects on mortality statistics. , 2001, Forensic science international.