论文信息 - Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist. - 字舞流文

Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.

Adam R. Johnson | P. Lockey | W. Ouyang | J. DeVoss | J. Lesch | H. Wong | Celine Eidenschenk | A. Gobbi | J. Hawkins | B. Fauber | Maxine Norman | Olivier René | Yuzhong Deng | H. La | S. Summerhill | C. Everett | Arunima Ganguli | Justin Lesch | Susan Summerhill