Impaired cerebral angiogenesis in the fetal lamb model of persistent pulmonary hypertension

[1]  A. Gunn,et al.  Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep , 2014, Journal of Neuroinflammation.

[2]  T. Hla,et al.  Post-transcriptional gene regulation by HuR and microRNAs in angiogenesis , 2014, Current opinion in hematology.

[3]  S. Bauersachs,et al.  Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle , 2013, International Journal of Developmental Neuroscience.

[4]  O. Makeyev,et al.  Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus , 2012, Neuroscience.

[5]  K. Pritchard,et al.  Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase. , 2011, American journal of physiology. Lung cellular and molecular physiology.

[6]  J. LaManna,et al.  Hypoxia-induced angiogenesis is delayed in aging mouse brain , 2011, Brain Research.

[7]  K. Barrington,et al.  Pulmonary hypertension and the asphyxiated newborn. , 2011, The Journal of pediatrics.

[8]  S. Sperling,et al.  Hypoxia inducible factor stabilization leads to lasting improvement of hippocampal memory in healthy mice , 2010, Behavioural Brain Research.

[9]  A. Rosenberg,et al.  School-age outcomes of newborns treated for persistent pulmonary hypertension , 2010, Journal of Perinatology.

[10]  F. Groenendaal,et al.  The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic–ischemic brain injury , 2009, Brain Research Reviews.

[11]  E. Marcotte,et al.  Global signatures of protein and mRNA expression levelsw , 2009 .

[12]  M. Gassmann,et al.  The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain , 2009, Brain and Development.

[13]  R. Teng,et al.  Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension. , 2009, American journal of physiology. Lung cellular and molecular physiology.

[14]  G. Konduri,et al.  Advances in the diagnosis and management of persistent pulmonary hypertension of the newborn. , 2009, Pediatric clinics of North America.

[15]  H. Kim,et al.  Dexamethasone coordinately regulates angiopoietin-1 and VEGF: a mechanism of glucocorticoid-induced stabilization of blood-brain barrier. , 2008, Biochemical and biophysical research communications.

[16]  M. Gassmann,et al.  HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam , 2008, Brain Research.

[17]  J. LaManna,et al.  Physiologic angiodynamics in the brain. , 2007, Antioxidants & redox signaling.

[18]  K. Pritchard,et al.  Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension. , 2007, American journal of physiology. Heart and circulatory physiology.

[19]  B. Vohr,et al.  Early inhaled nitric oxide therapy for term and near-term newborn infants with hypoxic respiratory failure: neurodevelopmental follow-up. , 2007, The Journal of pediatrics.

[20]  R. Wenger,et al.  Lack of Hypoxia-Inducible Factor-1α Impairs Midbrain Neural Precursor Cells Involving Vascular Endothelial Growth Factor Signaling , 2007, The Journal of Neuroscience.

[21]  J. LaManna,et al.  Structural and functional adaptation to hypoxia in the rat brain , 2004, Journal of Experimental Biology.

[22]  J. LaManna,et al.  Hypoxic Regulation of Angiopoietin-2 Expression in Endothelial Cells* , 2004, Journal of Biological Chemistry.

[23]  B. McManus,et al.  Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts. , 2003, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[24]  K. Jin,et al.  VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. , 2003, The Journal of clinical investigation.

[25]  N. Ferrara,et al.  The biology of VEGF and its receptors , 2003, Nature Medicine.

[26]  K. Pritchard,et al.  Decreased association of HSP90 impairs endothelial nitric oxide synthase in fetal lambs with persistent pulmonary hypertension. , 2003, American journal of physiology. Heart and circulatory physiology.

[27]  W. Stewart,et al.  Paracrine and Autocrine Functions of Neuronal Vascular Endothelial Growth Factor (VEGF) in the Central Nervous System* , 2002, The Journal of Biological Chemistry.

[28]  L. Ment,et al.  Astrocyte-derived VEGF mediates survival and tube stabilization of hypoxic brain microvascular endothelial cells in vitro. , 2001, Brain research. Developmental brain research.

[29]  M. Pfaffl,et al.  A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.

[30]  Michael I. Wilson,et al.  Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation , 2001, Science.

[31]  C. Wykoff,et al.  The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis , 1999, Nature.

[32]  L. Huang,et al.  Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway , 1998 .

[33]  J. LaManna,et al.  Ultrastructural concomitants of hypoxia-induced angiogenesis , 1997, Acta Neuropathologica.

[34]  N. Ferrara,et al.  The biology of vascular endothelial growth factor. , 1997, Endocrine reviews.

[35]  J. LaManna,et al.  Time-course and reversibility of the hypoxia-induced alterations in cerebral vascularity and cerebral capillary glucose transporter density , 1996, Brain Research.

[36]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Joseph C. LaManna,et al.  Architectural alterations in rat cerebral microvessels after hypobaric hypoxia , 1994, Brain Research.

[38]  H. Shim.  Hypoxia-Inducible Factor-1 , 2015 .

[39]  J. LaManna,et al.  Is cycloxygenase-2 (COX-2) a major component of the mechanism responsible for microvascular remodeling in the brain? , 2006, Advances in experimental medicine and biology.

[40]  S Rozen,et al.  Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.

[41]  M. Neri,et al.  An Immunohistochemical Study , 1992 .

[42]  S. Takashima,et al.  Immunohistochemical study of the vasculature in the developing brain. , 1991, Pediatric neurology.

[43]  C. Bernhard,et al.  On the prenatal development of function and structure in the somesthetic cortex of the sheep. , 1967, Progress in brain research.

[44]  R. Furlan,et al.  Open Access Research , 2022 .