The effectiveness of narrative exposure therapy: a review, meta-analysis and meta-regression analysis

ABSTRACT Background: Narrative exposure therapy (NET) is a short-term psychological treatment for post-traumatic stress disorder (PTSD) that has been investigated in various contexts among traumatized refugees and other trauma survivors. Sustained treatment results have been reported, but the methodological quality of the trials needs a more thorough examination. Objective: To evaluate the effectiveness of NET for survivors of trauma, using a quality assessment, an updated meta-analysis, and a meta-regression analysis. Method: Following a systematic literature selection, the methodological quality of the included studies was assessed; Non-controlled and controlled effect sizes (Hedges’ g) were estimated using a random effects model. Predictor analyses were performed. Non-controlled effect sizes for PTSD and depression included symptom change at post-treatment and follow-up time-points. Controlled effect sizes included post-treatment comparisons of NET with non-active and active comparators: both trauma-focused (TF) and non-trauma-focused (non-TF) interventions. Results: The selected studies showed high external validity; methodological quality was equivalent to other guideline-supported TF interventions. In 16 randomized controlled trials, involving 947 participants, large non-controlled effect sizes were found for PTSD symptoms, at post-treatment (g = 1.18, 95% confidence interval [0.87; 1.50]) and follow-up (g = 1.37 [0.96; 1.77]). For depression symptoms, medium non-controlled effect sizes were found, at post-treatment (g = 0.47 [0.23; 0.71]) and follow-up (g = 0.60 [0.26; 0.94]). Post-treatment, NET outperformed non-active comparators and non-TF active comparators for PTSD, but not the combined active comparators. For depression, NET only outperformed non-active comparators. Advancing age predicted better treatment results for PTSD and depression symptoms; a history of migration predicted smaller treatment results for depression symptoms. Conclusions:The findings of this meta-analysis suggest that patients and providers may expect sustained treatment results from NET. Controlled comparisons with other guideline-supported TF interventions are not yet available. HIGHLIGHTS • Narrative exposure therapy is effective in post-traumatic stress disorder symptom reduction at post-treatment (g = 1.18) and follow-up (g = 1.37).• Treatment results are better for older adults.• Controlled comparisons with other guideline-supported trauma-focused interventions are not yet available.

[1]  Eiko I. Fried,et al.  Moving Forward: Challenges and Directions for Psychopathological Network Theory and Methodology , 2017, Perspectives on psychological science : a journal of the Association for Psychological Science.

[2]  R. Kleber,et al.  Predicting post‐traumatic stress disorder treatment response in refugees: Multilevel analysis , 2017, The British journal of clinical psychology.

[3]  C. Barbui,et al.  Psychosocial interventions for post-traumatic stress disorder in refugees and asylum seekers resettled in high-income countries: Systematic review and meta-analysis , 2017, PloS one.

[4]  U. Tran,et al.  The relative efficacy of bona fide psychotherapies for post-traumatic stress disorder: a meta-analytical evaluation of randomized controlled trials , 2016, BMC Psychiatry.

[5]  B. Liddell,et al.  The Relationship Between Post-Migration Stress and Psychological Disorders in Refugees and Asylum Seekers , 2016, Current Psychiatry Reports.

[6]  R. van de Schoot,et al.  Eye movement desensitisation and reprocessing therapy v. stabilisation as usual for refugees: randomised controlled trial. , 2016, The British journal of psychiatry : the journal of mental science.

[7]  C. Forneris,et al.  Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis. , 2016, Clinical psychology review.

[8]  T. Elbert,et al.  Psychotherapies for PTSD: what do they have in common? , 2015, European journal of psychotraumatology.

[9]  N. Hunt,et al.  Randomised controlled study comparing two psychological therapies for Posttraumatic Stress Disorder (PTSD): Emotional Freedom Techniques (EFT) vs. Narrative Exposure Therapy (NET) , 2015 .

[10]  M. Alghamdi,et al.  The effectiveness of Narrative Exposure Therapy with traumatised firefighters in Saudi Arabia: a randomized controlled study. , 2015, Behaviour research and therapy.

[11]  Nexhmedin Morina,et al.  Meta-analysis of psychological treatments for posttraumatic stress disorder in adult survivors of childhood abuse. , 2014, Clinical psychology review.

[12]  N. Patel,et al.  Psychological, social and welfare interventions for psychological health and well-being of torture survivors. , 2014, The Cochrane database of systematic reviews.

[13]  T. Elbert,et al.  Dissemination of Psychotherapy for Trauma Spectrum Disorders in Postconflict Settings: A Randomized Controlled Trial in Rwanda , 2014, Psychotherapy and Psychosomatics.

[14]  T. Cox,et al.  Adapting narrative exposure therapy for Chinese earthquake survivors: a pilot randomised controlled feasibility study , 2014, BMC Psychiatry.

[15]  T. Elbert,et al.  Effects of Psychotherapy on DNA Strand Break Accumulation Originating from Traumatic Stress , 2014, Psychotherapy and Psychosomatics.

[16]  K. Pargament,et al.  A comparison of Narrative Exposure Therapy and Prolonged Exposure therapy for PTSD. , 2014, Clinical psychology review.

[17]  T. Elbert,et al.  The effect of trauma-focused therapy on the altered T cell distribution in individuals with PTSD: evidence from a randomized controlled trial. , 2014, Journal of psychiatric research.

[18]  A. Heinz,et al.  Evaluating interventions for posttraumatic stress disorder in low and middle income countries: Narrative Exposure Therapy , 2014 .

[19]  J. Barth,et al.  Specific and nonspecific psychological interventions for PTSD symptoms: a meta-analysis with problem complexity as a moderator. , 2014, Journal of clinical psychology.

[20]  L. Rapport,et al.  Brief narrative exposure therapy for posttraumatic stress in Iraqi refugees: a preliminary randomized clinical trial. , 2014, Journal of traumatic stress.

[21]  Michelle Lonergan Cognitive Behavioral Therapy for PTSD: The Role of Complex PTSD on Treatment Outcome , 2014 .

[22]  N. Ford,et al.  The efficacy of psychosocial interventions for adults in contexts of ongoing man-made violence - A systematic review. , 2014 .

[23]  T. Elbert,et al.  Gender and offender status predicting treatment success in refugees and asylum seekers with PTSD , 2014, European journal of psychotraumatology.

[24]  C. Lewis,et al.  Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults. , 2013, The Cochrane database of systematic reviews.

[25]  T. Elbert,et al.  Treating PTSD in refugees and asylum seekers within the general health care system. A randomized controlled multicenter study. , 2013, Behaviour research and therapy.

[26]  P. Schnurr,et al.  Meta-analysis of the efficacy of treatments for posttraumatic stress disorder. , 2013, The Journal of clinical psychiatry.

[27]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[28]  E. Youngstrom,et al.  The co-occurrence of major depressive disorder among individuals with posttraumatic stress disorder: a meta-analysis. , 2013, Journal of traumatic stress.

[29]  T. Cox,et al.  A randomised controlled pilot study: the effectiveness of narrative exposure therapy with adult survivors of the Sichuan earthquake , 2013, BMC Psychiatry.

[30]  B. McEwen,et al.  Brain on stress: How the social environment gets under the skin , 2012, Proceedings of the National Academy of Sciences.

[31]  M. Hatem,et al.  Cognitive-Behavioral Therapy versus Other PTSD Psychotherapies as Treatment for Women Victims of War-Related Violence: A Systematic Review , 2012, TheScientificWorldJournal.

[32]  J. Reitsma,et al.  Brief eclectic psychotherapy v. eye movement desensitisation and reprocessing therapy for post-traumatic stress disorder: randomised controlled trial. , 2012, The British journal of psychiatry : the journal of mental science.

[33]  W. Rief,et al.  Lifetime Traumatic Experiences and Posttraumatic Stress Disorder in the German Population: Results of a Representative Population Survey , 2011, The Journal of nervous and mental disease.

[34]  J. Sterne,et al.  The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials , 2011, BMJ : British Medical Journal.

[35]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[36]  T. Elbert,et al.  Treatment of Traumatized Victims of War and Torture: A Randomized Controlled Comparison of Narrative Exposure Therapy and Stress Inoculation Training , 2011, Psychotherapy and Psychosomatics.

[37]  T. Elbert,et al.  Community-implemented trauma therapy for former child soldiers in Northern Uganda: a randomized controlled trial. , 2011, JAMA.

[38]  C. Hoge Interventions for war-related posttraumatic stress disorder: meeting veterans where they are. , 2011, JAMA.

[39]  A. Elklit,et al.  Psychosocial treatment of posttraumatic stress disorder in adult refugees: a systematic review of prospective treatment outcome studies and a critique. , 2011, Journal of affective disorders.

[40]  Z. Steel,et al.  A critical review of psychological treatments of posttraumatic stress disorder in refugees. , 2011, Clinical psychology review.

[41]  Zac E. Imel,et al.  Determining what works in the treatment of PTSD. , 2010, Clinical psychology review.

[42]  Mina Fazel,et al.  The emerging evidence for Narrative Exposure Therapy: a review. , 2010, Clinical psychology review.

[43]  T. Elbert,et al.  Can Asylum-Seekers with Posttraumatic Stress Disorder Be Successfully Treated? A Randomized Controlled Pilot Study , 2010, Cognitive behaviour therapy.

[44]  Shireen L. Rizvi,et al.  Cognitive and affective predictors of treatment outcome in Cognitive Processing Therapy and Prolonged Exposure for posttraumatic stress disorder. , 2009, Behaviour research and therapy.

[45]  Z. Steel,et al.  Association of torture and other potentially traumatic events with mental health outcomes among populations exposed to mass conflict and displacement: a systematic review and meta-analysis. , 2009, JAMA.

[46]  T. Elbert,et al.  Narrative Exposure Therapy versus Interpersonal Psychotherapy , 2009, Psychotherapy and Psychosomatics.

[47]  P. Schnurr,et al.  A Guide to the Literature on Psychotherapy for PTSD , 2009 .

[48]  T. Elbert,et al.  Treatment of posttraumatic stress disorder by trained lay counselors in an African refugee settlement: a randomized controlled trial. , 2008, Journal of consulting and clinical psychology.

[49]  T. Elbert,et al.  Narrative exposure therapy for political imprisonment-related chronic posttraumatic stress disorder and depression. , 2007, Behaviour research and therapy.

[50]  Thomas Elbert,et al.  Narrative exposure therapy : a short-term intervention for traumatic stress disorders , 2005 .

[51]  R. Bradley,et al.  A multidimensional meta-analysis of psychotherapy for PTSD. , 2005, The American journal of psychiatry.

[52]  T. Elbert,et al.  A comparison of narrative exposure therapy, supportive counseling, and psychoeducation for treating posttraumatic stress disorder in an african refugee settlement. , 2004, Journal of consulting and clinical psychology.

[53]  R. Kleber,et al.  A need for ethnic similarity in the therapist-patient interaction? Mediterranean migrants in Dutch mental-health care. , 2004, Journal of clinical psychology.

[54]  C. Bell Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision: DSM-IV-TR Quick Reference to the Diagnostic Criteria from DSM-IV-TR , 2001 .

[55]  S Duval,et al.  Trim and Fill: A Simple Funnel‐Plot–Based Method of Testing and Adjusting for Publication Bias in Meta‐Analysis , 2000, Biometrics.

[56]  N. Tarrier,et al.  Factors associated with outcome of cognitive-behavioural treatment of chronic post-traumatic stress disorder. , 2000, Behaviour research and therapy.

[57]  Jacob Cohen,et al.  A power primer. , 1992, Psychological bulletin.

[58]  D. Brom,et al.  Brief psychotherapy for posttraumatic stress disorders. , 1989, Journal of consulting and clinical psychology.

[59]  Summary of the clinical practice guideline for the treatment of posttraumatic stress disorder (PTSD) in adults. , 2019, The American psychologist.

[60]  O. Alhassoon,et al.  Trauma-focused therapy for refugees: meta-analytic findings. , 2015, Journal of counseling psychology.

[61]  M. Carter Diagnostic and Statistical Manual of Mental Disorders, 5th ed. , 2014 .

[62]  L. Mehl-Madrona,et al.  Meta-analysis of the use of narrative exposure therapy for the effects of trauma among refugee populations. , 2013, The Permanente journal.

[63]  Dc Washington Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[64]  Jacob Cohen,et al.  QUANTITATIVE METHODS IN PSYCHOLOGY A Power Primer , 1992 .

[65]  Jacob Cohen,et al.  Quantitative Methods in Psychology , 1938, Nature.