Docking and ADMET studies for investigating the anticancer potency of Moscatilin on APC10/DOC1 and PKM2 against five clinical drugs
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[1] H. Mukhtar,et al. Cassia fistula Leaves; UHPLC-QTOF-MS/MS Based Metabolite Profiling and Molecular Docking Insights to Explore Bioactives Role towards Inhibition of Pancreatic Lipase , 2021, Plants.
[2] K. Satyamoorthy,et al. Cytotoxicity and radiosensitizing potency of Moscatilin in cancer cells at low radiation doses of X-ray and UV-C , 2021, 3 Biotech.
[3] L. A. Al Kury,et al. Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets , 2020, Molecules.
[4] C. Wongkham,et al. Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines , 2020, AntiCancer Research.
[5] Alexander Fanourakis,et al. Recent Developments in Enantioselective Transition Metal Catalysis Featuring Attractive Noncovalent Interactions between Ligand and Substrate , 2020, ACS catalysis.
[6] Sagar D Khare,et al. Recent progress in designing protein-based supramolecular assemblies. , 2020, Current opinion in structural biology.
[7] Mahdi Shafiei,et al. Solvent-Solvent Correlations across Graphene: The Effect of Image Charges. , 2020, ACS nano.
[8] William O. Meeker,et al. Evaluating the involvement of tryptophan on thiolated peptide-mercury(II) complexes: Cation-pi interactions , 2020, Inorganica Chimica Acta.
[9] Renxiao Wang,et al. Prediction of the Favorable Hydration Sites in a Protein Binding Pocket and Its Application to Scoring Function Formulation , 2020, J. Chem. Inf. Model..
[10] M. Ceccarelli,et al. Resveratrol in Cancer Patients: From Bench to Bedside , 2020, International journal of molecular sciences.
[11] C. Jung,et al. Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation , 2020, Nutrients.
[12] V. Cardile,et al. Moscatilin, a bibenzyl derivative from the orchid Dendrobium loddigesii, induces apoptosis in melanoma cells. , 2020, Chemico-biological interactions.
[13] M. Summers,et al. APC/C ubiquitin ligase: functions and mechanisms in tumorigenesis. , 2020, Seminars in cancer biology.
[14] Ashish,et al. Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis , 2020, Frontiers in Oncology.
[15] R. Gan,et al. Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review , 2020, Foods.
[16] C. Murali Krishna,et al. Functionalized Alpha‐lactalbumin Conjugated with Gold Nanoparticle for Targeted Drug Delivery , 2020 .
[17] R. Meijboom,et al. Review of supported metal nanoparticles: synthesis methodologies, advantages and application as catalysts , 2020, Journal of Materials Science.
[18] G. Bifulco,et al. Advances in paclitaxel combinations for treating cervical cancer , 2020, Expert opinion on pharmacotherapy.
[19] Jin-Baek Kim,et al. Moscatilin Induces Apoptosis in Human Head and Neck Squamous Cell Carcinoma Cells via JNK Signaling Pathway , 2020, Molecules.
[20] Genlou Sun,et al. MicroRNA-mediated responses to colchicine treatment in barley , 2020, Planta.
[21] A. Anighoro. Underappreciated Chemical Interactions in Protein-Ligand Complexes. , 2020, Methods in molecular biology.
[22] P. Melloy. The anaphase‐promoting complex: A key mitotic regulator associated with somatic mutations occurring in cancer , 2020, Genes, chromosomes & cancer.
[23] Ze Zhang,et al. PKM2, function and expression and regulation , 2019, Cell & Bioscience.
[24] K. Zen,et al. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis , 2018, Scientific Reports.
[25] U. Kneser,et al. The combination of mitomycin-induced blood cells with a temporary treatment of ciclosporin A prolongs allograft survival in vascularized composite allotransplantation , 2018, Langenbeck's Archives of Surgery.
[26] Publisher's Note , 2018, Anaesthesia.
[27] Olivier Michielin,et al. SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules , 2017, Scientific Reports.
[28] D. Jin,et al. Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway , 2017, Molecular medicine reports.
[29] K. Satyamoorthy,et al. Dendrobium protoplast co-culture promotes phytochemical assemblage in vitro , 2016, Protoplasma.
[30] B. Sritularak,et al. Moscatilin inhibits epithelial-to-mesenchymal transition and sensitizes anoikis in human lung cancer H460 cells , 2015, Journal of Natural Medicines.
[31] Hen-Hong Chang,et al. Moscatilin induces apoptosis and mitotic catastrophe in human esophageal cancer cells. , 2013, Journal of medicinal food.
[32] Jie Shen,et al. admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties , 2012, J. Chem. Inf. Model..
[33] C. Teng,et al. Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway , 2012, Journal of Molecular Medicine.
[34] Y. Wang,et al. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2 , 2011, Oncogene.
[35] Hui-Lung Sun,et al. Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo. , 2010, Cancer letters.
[36] C. Pritsos,et al. Mitomycin C Inhibits Ribosomal RNA , 2010, Journal of Biological Chemistry.
[37] C. Teng,et al. Moscatilin Induces Apoptosis in Human Colorectal Cancer Cells: A Crucial Role of c-Jun NH2-Terminal Protein Kinase Activation Caused by Tubulin Depolymerization and DNA Damage , 2008, Clinical Cancer Research.
[38] Ruth Nussinov,et al. FireDock: a web server for fast interaction refinement in molecular docking† , 2008, Nucleic Acids Res..
[39] Arvind Saklani,et al. Plant-derived compounds in clinical trials. , 2008, Drug discovery today.
[40] Ruth Nussinov,et al. PatchDock and SymmDock: servers for rigid and symmetric docking , 2005, Nucleic Acids Res..
[41] JalpaKailasbhai Patel,et al. Distant and Delayed Mitomycin C Extravasation , 1999, Pharmacotherapy.