Decreased Administration of Life-Sustaining Treatment just before Death among Older Inpatients in Japan: A Time-Trend Analysis from 2012 through 2014 Based on a Nationally Representative Sample

The administration of intensive end-of-life care just before death in older patients has become a major policy concern, as it increases medical costs; however, care intensity does not necessarily indicate quality. This study aimed to describe the temporal trends in the administration of life-sustaining treatments (LSTs) and intensive care unit (ICU) admissions just before death in older inpatients in Japan. We utilized the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB). Inpatients who were aged ≥65 years and died in October of 2012, 2013, or 2014 were analyzed. The numbers of decedents in 2012, 2013, and 2014 were 3362, 3473, and 3516, respectively. The frequencies of receiving cardiopulmonary resuscitation (CPR) (11.0% to 8.3%), mechanical ventilation (MV) (13.1% to 9.8%), central venous catheter (CVC) insertion (10.6% to 7.8%), and ICU admission (9.1% to 7.8%), declined between 2012 and 2014. After adjusting for age, sex, and type of ward, the declining trends persisted for CPR, MV, and CVC insertion relative to the frequencies in 2012. Our results indicate that the administration of LST just before death in older inpatients in Japan decreased from 2012 to 2014.

[1]  S. Fukui,et al.  A Review of Advance Care Planning in Research and Clinical Settings , 2019, Palliative Care Research.

[2]  J. Curtis,et al.  Temporal Trends Between 2010 and 2015 in Intensity of Care at End-of-Life for Patients With Chronic Illness: Influence of Age Under vs. Over 65 Years. , 2018, Journal of pain and symptom management.

[3]  Joann Ahrens,et al.  Financing End-of-Life Care in the USA , 2001, Journal of the Royal Society of Medicine.

[4]  C. Sprung,et al.  Changes in End-of-Life Practices in European Intensive Care Units From 1999 to 2016. , 2019, JAMA.

[5]  A. Torke,et al.  Factors associated with family satisfaction with end-of-life care in the ICU: a systematic review. , 2015, Chest.

[6]  Pall Med,et al.  Dying in America: improving quality and honoring individual preferences near the end of life. , 2015, Military medicine.

[7]  J. Guralnik,et al.  Patterns of functional decline at the end of life. , 2003, JAMA.

[8]  J. Petermans,et al.  [End of life care in the elderly]. , 2014, Revue medicale de Liege.

[9]  Jessica Ogarek,et al.  Site of Death, Place of Care, and Health Care Transitions Among US Medicare Beneficiaries, 2000-2015 , 2018, JAMA.

[10]  Sangwook Kang,et al.  Intensity of Care at the End of Life Among Older Adults in Korea , 2018, Journal of palliative care.

[11]  T. Fukawa Inpatient Expenditure of the Decedent Elderly in Japan , 2016 .

[12]  K. Hillman,et al.  Non-beneficial treatments in hospital at the end of life: a systematic review on extent of the problem. , 2016, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[13]  Tomohiro Kuroda,et al.  Analysis of the evidence-practice gap to facilitate proper medical care for the elderly: investigation, using databases, of utilization measures for National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) , 2017, Environmental Health and Preventive Medicine.

[14]  L. Radbruch,et al.  The quality of death: ranking end-of-life care across the world , 2010 .

[15]  L. Trinquart,et al.  Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade* , 2010, Critical care medicine.

[16]  達也 森田,et al.  遺族による終末期がん患者への緩和ケアの質の評価のための全国調査:the Japan Hospice and Palliative Care Evaluation 2 study (J-HOPE2 study) , 2016 .

[17]  M. Mcclellan,et al.  Trends in inpatient treatment intensity among Medicare beneficiaries at the end of life. , 2004, Health services research.

[18]  J. Langton,et al.  Retrospective studies of end-of-life resource utilization and costs in cancer care using health administrative data: A systematic review , 2014, Palliative medicine.

[19]  Donna M. Wilson,et al.  Should the oldest-old be admitted to the intensive care unit and receive advanced life-supporting care? , 2010, Critical care medicine.

[20]  H. Nakano,et al.  Position statement from the Japan Geriatrics Society 2012: End‐of‐life care for the elderly , 2014, Geriatrics & Gerontology International.

[21]  A. Laupacis,et al.  Trends in site of death and health care utilization at the end of life: a population-based cohort study. , 2019, CMAJ open.

[22]  V. Tschudin Book Review: Withholding and withdrawing life-prolonging medical treatment: guidance for decision making , 2000 .

[23]  Jenq-Wen Huang,et al.  Withdrawal from long-term hemodialysis in patients with end-stage renal disease in Taiwan. , 2013, Journal of the Formosan Medical Association = Taiwan yi zhi.

[24]  T. Nakayama,et al.  Validation of claims data to identify death among aged persons utilizing enrollment data from health insurance unions , 2019, Environmental Health and Preventive Medicine.

[25]  M. Egger,et al.  Measuring Intensity of End of Life Care: A Systematic Review , 2015, PloS one.

[26]  H. Wunsch,et al.  Variation in critical care services across North America and Western Europe* , 2008, Critical care medicine.

[27]  I. Higginson,et al.  Better palliative care for older people , 2004 .