Stabilization of GATA3 Polycomb Group Gene bmi-1 through the Regulation of Th2 Cell Development by

Lohuizen, Masakatsu Yamashita and Toshinori NakayamaAkane Suzuki, Takako Miki, Haruhiko Koseki, Maarten van Hiroyuki Hosokawa, Motoko Y. Kimura, Ryo Shinnakasu,http://www.jimmunol.org/content/177/11/7656J Immunol€2006; 177:7656-7664; ;Referenceshttp://www.jimmunol.org/content/177/11/7656.full#ref-list-1This article cites 54 articles, 17 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online at: Permissionshttp://www.aai.org/ji/copyright.htmlSubmit copyright permission requests at: Email Alertshttp://jimmunol.org/cgi/alerts/etocReceive free email-alerts when new articles cite this article. Sign up at:

[1]  R. DePinho,et al.  The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus , 1999, Nature.

[2]  A. Iwama,et al.  Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. , 2004, Immunity.

[3]  M. Frasch,et al.  Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2 , 1991, Nature.

[4]  S. Szabo,et al.  Distinct Effects of T-bet in TH1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells , 2002, Science.

[5]  M. Lohuizen,et al.  Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas , 2004, Nature.

[6]  R. Perlmutter,et al.  T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M. Karin,et al.  Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. , 1997, The New England journal of medicine.

[8]  M. Su,et al.  Interferon‐γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway , 1998, The EMBO journal.

[9]  A. Heimberger,et al.  Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. , 1990, Science.

[10]  S. Ishii,et al.  Regulation of T helper type 2 cell differentiation by murine Schnurri-2 , 2005, The Journal of experimental medicine.

[11]  S. Morrison,et al.  Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.

[12]  Masato Ogata,et al.  Ras-ERK MAPK Cascade Regulates GATA3 Stability and Th2 Differentiation through Ubiquitin-Proteasome Pathway* , 2005, Journal of Biological Chemistry.

[13]  A. Otte,et al.  Polycomb group protein complexes: do different complexes regulate distinct target genes? , 1999, Biochimica et biophysica acta.

[14]  T. Kamata,et al.  T Cell Receptor–Induced Calcineurin Activation Regulates T Helper Type 2 Cell Development by Modifying the Interleukin 4 Receptor Signaling Complex , 2000, The Journal of experimental medicine.

[15]  Maki Ukai-Tadenuma,et al.  CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. , 2003, Immunity.

[16]  A. O’Garra,et al.  Cytokines induce the development of functionally heterogeneous T helper cell subsets. , 1998, Immunity.

[17]  B. Chait,et al.  Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement , 2003, Nature Immunology.

[18]  Andreas Radbruch,et al.  Cytokine memory of T helper lymphocytes. , 2002, Advances in immunology.

[19]  Irving L. Weissman,et al.  Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.

[20]  A. Rao,et al.  Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[21]  T. Kitamura,et al.  Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. , 2001, Immunity.

[22]  L Adorini,et al.  The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses. , 1998, Annual review of immunology.

[23]  R. Flavell,et al.  Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. , 1998, Immunity.

[24]  M. Lohuizen.  The trithorax-group and polycomb-group chromatin modifiers: implications for disease. , 1999 .

[25]  Richard A Flavell,et al.  The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells , 1997, Cell.

[26]  Brigitte Wild,et al.  Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex , 2002, Cell.

[27]  V. Pirrotta,et al.  Drosophila Enhancer of Zeste/ESC Complexes Have a Histone H3 Methyltransferase Activity that Marks Chromosomal Polycomb Sites , 2002, Cell.

[28]  M. Sofroniew,et al.  Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. , 1994, Genes & development.

[29]  S. Constant,et al.  Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. , 1997, Annual review of immunology.

[30]  Hengbin Wang,et al.  Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing , 2002, Science.

[31]  A Radbruch,et al.  Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. , 2000, Immunity.

[32]  A. Otte,et al.  Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation , 1999, Nature Genetics.

[33]  M. Miyazaki,et al.  Ras Activation in T Cells Determines the Development of Antigen-Induced Airway Hyperresponsiveness and Eosinophilic Inflammation1 , 2002, The Journal of Immunology.

[34]  M. Vidal,et al.  Role of histone H2A ubiquitination in Polycomb silencing , 2004, Nature.

[35]  W. Paul,et al.  The IL-4 receptor: signaling mechanisms and biologic functions. , 1999, Annual review of immunology.

[36]  F. Martinon,et al.  Antigen-independent, integrin-mediated T cell activation. , 1995, Journal of immunology.

[37]  Prabir Ray,et al.  A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation , 2001, Nature Immunology.

[38]  W. Paul,et al.  Acquisition of lymphokine-producing phenotype by CD4+ T cells. , 1994, Annual review of immunology.

[39]  L. Hu,et al.  The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors. , 1997, Immunity.

[40]  M. Taniguchi,et al.  CD28 Costimulation Controls Histone Hyperacetylation of the Interleukin 5 Gene Locus in Developing Th2 Cells* , 2004, Journal of Biological Chemistry.

[41]  R. Coffman,et al.  TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.

[42]  Naoko Arai,et al.  Gata-3 Induces T Helper Cell Type 2 (Th2) Cytokine Expression and Chromatin Remodeling in Committed Th1 Cells , 2000, The Journal of experimental medicine.

[43]  W. Ouyang,et al.  Signaling and transcription in T helper development. , 2000, Annual review of immunology.

[44]  Masakatsu Yamashita,et al.  Identification of a Conserved GATA3 Response Element Upstream Proximal from the Interleukin-13 Gene Locus* 210 , 2002, The Journal of Biological Chemistry.

[45]  R. Locksley,et al.  The regulation of immunity to Leishmania major. , 1995, Annual review of immunology.

[46]  Haruhiko Koseki,et al.  Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. , 2004, Developmental cell.

[47]  D. Reinberg,et al.  Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. , 2002, Genes & development.

[48]  Yamamura Ken-ichi,et al.  Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .

[49]  G. Sauvageau,et al.  Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells , 2003, Nature.

[50]  R. Flavell,et al.  Defective T cell differentiation in the absence of Jnk1. , 1998, Science.

[51]  S. Akira,et al.  Essential role of Stat6 in IL-4 signalling , 1996, Nature.

[52]  M. Lohuizen,et al.  Stem Cells and Cancer The Polycomb Connection , 2004, Cell.

[53]  A. Rao,et al.  An epigenetic view of helper T cell differentiation , 2003, Nature Immunology.

[54]  R. Balling,et al.  A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. , 1996, Development.