Effect of collaborative dementia care on potentially inappropriate medication use: Outcomes from the Care Ecosystem randomized clinical trial

Potentially inappropriate medications (PIMs) cause adverse events and death. We evaluate the Care Ecosystem (CE) collaborative dementia care program on medication use among community‐dwelling persons living with dementia (PLWD).

[1]  C. Boyd,et al.  Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians , 2022, JAMA internal medicine.

[2]  N. Herrmann,et al.  CCCDTD5 recommendations on the deprescribing of cognitive enhancers in dementia , 2022, Alzheimer's & dementia.

[3]  K. Yaffe,et al.  Polypharmacy among older adults with dementia compared with those without dementia in the United States , 2021, Journal of the American Geriatrics Society.

[4]  K. Langa,et al.  Prevalence of Central Nervous System-Active Polypharmacy Among Older Adults With Dementia in the US. , 2021, JAMA.

[5]  M. Kuzuya,et al.  Use of Anti-Dementia Drugs Reduces the Risk of Potentially Inappropriate Medications: A Secondary Analysis of a Nationwide Survey of Prescribing Pharmacies , 2020, Dementia and Geriatric Cognitive Disorders.

[6]  D. Melzer,et al.  Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes. , 2020, Age and ageing.

[7]  T. Wilt,et al.  Care Interventions for People Living With Dementia and Their Caregivers , 2020 .

[8]  Naaheed Mukadam,et al.  Dementia prevention, intervention, and care: 2020 report of the Lancet Commission , 2020, The Lancet.

[9]  L. Flicker,et al.  Optimisation of medications used in residential aged care facilities: a systematic review and meta-analysis of randomised controlled trials , 2020, BMC Geriatrics.

[10]  B. Lawlor,et al.  Potentially inappropriate medication use in older adults with mild-moderate Alzheimer's disease: prevalence and associations with adverse events. , 2020, Age and ageing.

[11]  Amy E. Sanders,et al.  Quality Improvement in Dementia Care: Dementia Management Quality Measurement Set 2018 Implementation Update. , 2020, The American journal of psychiatry.

[12]  Y. Loke,et al.  Interventions to Reduce Anticholinergic Burden in Adults Aged 65 and Older: A Systematic Review. , 2020, Journal of the American Medical Directors Association.

[13]  L. Clare,et al.  Potentially inappropriate prescribing in dementia: a state-of-the-art review since 2007 , 2020, BMJ Open.

[14]  J. Schnipper,et al.  A systematic overview of systematic reviews evaluating interventions addressing polypharmacy. , 2019, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[15]  S. Bonasera,et al.  Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial. , 2019, JAMA internal medicine.

[16]  S. Bonasera,et al.  The Role of Care Navigators Working with People with Dementia and Their Caregivers. , 2019, Journal of Alzheimer's disease : JAD.

[17]  S. Bonasera,et al.  Variations in Costs of a Collaborative Care Model for Dementia , 2019, Journal of the American Geriatrics Society.

[18]  J. Hanlon,et al.  American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults , 2019, Journal of the American Geriatrics Society.

[19]  U. Macleod,et al.  Identifying potentially inappropriate prescribing in older people with dementia: a systematic review , 2019, European Journal of Clinical Pharmacology.

[20]  Robyn Tamblyn,et al.  Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial , 2018, JAMA.

[21]  D. Gerritsen,et al.  The effect of biannual medication reviews on the appropriateness of psychotropic drug use for neuropsychiatric symptoms in patients with dementia: a randomised controlled trial , 2018, Age and ageing.

[22]  M. Boustani,et al.  Ongoing Medical Management to Maximize Health and Well-being for Persons Living With Dementia , 2018, The Gerontologist.

[23]  Stefan Teipel,et al.  Effectiveness and Safety of Dementia Care Management in Primary Care: A Randomized Clinical Trial , 2017, JAMA psychiatry.

[24]  G. Jicha,et al.  Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden , 2017, Alzheimer's Research & Therapy.

[25]  Linda Lee,et al.  Use of potentially inappropriate medications among ambulatory home-dwelling elderly patients with dementia: A review of the literature , 2017, Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC.

[26]  C. Parsons Polypharmacy and inappropriate medication use in patients with dementia: an underresearched problem , 2017, Therapeutic advances in drug safety.

[27]  J. Galvin The Quick Dementia Rating System (QDRS): A rapid dementia staging tool , 2015, Alzheimer's & dementia.

[28]  L. Schneider,et al.  Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm. , 2015, JAMA psychiatry.

[29]  Sascha Dublin,et al.  Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. , 2015, JAMA internal medicine.

[30]  S. Yusuf,et al.  The burden of disease in older people and implications for health policy and practice , 2015, The Lancet.

[31]  L. Thabane,et al.  Empirical comparison of four baseline covariate adjustment methods in analysis of continuous outcomes in randomized controlled trials , 2014, Clinical epidemiology.

[32]  Antoni Sicras-Mainar,et al.  Comorbidity of dementia: a cross-sectional study of primary care older patients , 2014, BMC Psychiatry.

[33]  Ann M. Philbrick,et al.  Medication reconciliation by clinical pharmacists in an outpatient family medicine clinic. , 2014, Journal of the American Pharmacists Association : JAPhA.

[34]  Amy E. Sanders,et al.  Quality Improvement in Neurology: Dementia Management Quality Measures (Executive Summary) , 2013, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[35]  S. Simon,et al.  Medication discrepancies in integrated electronic health records , 2012, BMJ quality & safety.

[36]  T. Furukawa,et al.  How to Obtain NNT from Cohen's d: Comparison of Two Methods , 2011, PloS one.

[37]  M. Boustani,et al.  Impact of anticholinergics on the aging brain: a review and practical application , 2008 .

[38]  D. Meltzer,et al.  Use of a Self-Report-Generated Charlson Comorbidity Index for Predicting Mortality , 2005, Medical care.

[39]  D. Altman,et al.  Analysing controlled trials with baseline and follow up measurements , 2001, BMJ : British Medical Journal.

[40]  M. Kelly,et al.  Medication discrepancies in an outpatient electronic medical record. , 2001, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[41]  Michael H. Connors,et al.  Potentially Inappropriate Medication, Anticholinergic Burden, and Mortality in People Attending Memory Clinics. , 2017, Journal of Alzheimer's disease : JAD.

[42]  C. Hughes,et al.  Potentially Inappropriate Prescribing Among People with Dementia in Primary Care: A Retrospective Cross-Sectional Study Using the Enhanced Prescribing Database. , 2016, Journal of Alzheimer's disease : JAD.

[43]  C. Steiner,et al.  Comorbidity measures for use with administrative data. , 1998, Medical care.

[44]  R. Little A Test of Missing Completely at Random for Multivariate Data with Missing Values , 1988 .