论文信息 - Design and Syntheses of Novel Calix[4](aza)crowns: Neutral Receptors for α‐Amino Acids

Design and Syntheses of Novel Calix[4](aza)crowns: Neutral Receptors for α‐Amino Acids

Abstract A series of novel calix[4](aza)crowns 2a–2d containing acylhydrazone groups was designed and synthesized via 1+1 condensation of calix[4]‐1,3‐substituted benzaldehyde derivative 1 with bis‐hydrazides in 85–90% yields. They showed good complexation abilities toward α‐amino acids and exhibited complexation selectivity toward tryptophane.

Fafu Yang | Hongyu Guo | Jianrong Lin | Q. Peng | Y. Ji

[1] M. Goto,et al. Dominant factors affecting extraction behavior of amino compounds by a calix[6]arene carboxylic acid derivative , 2004 .

[2] Fafu Yang,et al. Design and Syntheses of Novel Calix[4]crown: Calix[4]‐Dixanthates‐Crowns , 2004 .

[3] A. I. Oliva,et al. A xanthone-based neutral receptor for zwitterionic amino acids , 2003 .

[4] A. Coleman,et al. Synthesis and complexation properties towards amino acids of mono-substituted p-sulphonato-calix-[n]-arenes , 2003 .

[5] M. Goto,et al. Liquid membrane transport of amino acids by a calix[6]arene carboxylic acid derivative , 2003 .

[6] Z. Asfari,et al. Synthesis of tripodal aza crown ether calix[4]arenes and their supramolecular chemistry with transition-, alkali metal ions and anions , 2002 .

[7] G. Fang,et al. Determination of eight essential amino acids in mixtures by chemometrics–spectrophotometry without separation , 2001 .

[8] Z. Asfari,et al. Aza crown ether calix[4]arenes containing cation and anion binding sites: effects of metal ions towards anion binding ability , 2001 .

[9] A. Konovalov. Calix[4]arene based α-aminophosphonates: Novel carriers for Zwitterionic amino acids transport , 1997 .

[10] V. Böhmer,et al. Calixarenes, Macrocycles with (Almost) Unlimited Possibilities , 1995 .