Open Reduction and Internal Fixation Using Double Plating with Biological and Artificial Bone Grafting of Aseptic Non-unions of the Distal Humerus: Clinical Results

Abstract Aim Intra-articular non-union of fractures is an uncommon but complex problem because in general, it is characterised by marked instability, pain, strength loss and significant functional limitation. The aim of this study is to report our prospective medium-term outcomes of the treatment of intra-articular, distal humeral aseptic non-unions using open reduction and internal fixation, augmented with artificial bone. Materials and methods A retrospective case series of 16 patients with intra-articular, aseptic non-unions of the distal humerus was analysed for range of motion, pain, Mayo Elbow Performance Scores (MEPS) and Oxford Elbow Scores (OES) after 12 months. Mean age was 44 years (range, 18–84 years) and mean total follow-up was 43 months (range, 24–62 months). Results All subjective and objective scores were significantly higher 12 months after treatment with internal fixation and artificial bone augmentation; the mean improvement on the MEPS was 18 points and 17 points on the OES. All patients returned to work, most without limitations. Autografts had worse outcomes compared to allografts regarding post-operative pain and time to return to work. No adverse events related to the artificial bone augmentation were seen and all fractures consolidated. Conclusion The use of two locking plates and bone graft augmentation with autografts or allografts with artificial bone grafts is a successful treatment of intra-articular distal humeral non-unions after hardware failure or biological limitations. Clinical significance The use of artificial bone in the treatment of septic non-unions of the upper limb is safe. When no autograft is possible because of concurrent morbidity, it can be used alone or combined with an allograft to reconstruct the affected bone without leading to extra morbidity or complications. How to cite this article Rollo G, Vicenti G, Rotini R, et al. Open Reduction and Internal Fixation Using Double Plating with Biological and Artificial Bone Grafting of Aseptic Non-unions of the Distal Humerus: Clinical Results. Strategies Trauma Limb Reconstr 2021;16(3):144–151.

[1]  D. Eygendaal,et al.  Global trends in indications for total elbow arthroplasty: a systematic review of national registries , 2020, EFORT open reviews.

[2]  G. Rollo,et al.  Grafting and fixation after aseptic non-union of the humeral shaft: A case series. , 2020, Journal of clinical orthopaedics and trauma.

[3]  G. Rollo,et al.  Plate-and-bone-strut fixation of distal third humeral shaft aseptic non-unions: A consecutive case series. , 2019, Journal of clinical orthopaedics and trauma.

[4]  Gina Lisignoli,et al.  Biomaterials: Foreign Bodies or Tuners for the Immune Response? , 2019, International journal of molecular sciences.

[5]  G. Rollo,et al.  Effect of trochleocapitellar index on adult patient-reported outcomes after noncomminuted intra-articular distal humeral fractures. , 2018, Journal of shoulder and elbow surgery.

[6]  L. Macchiarola,et al.  Grafting and fixation of proximal humeral aseptic non union: a prospective case series. , 2017, Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases.

[7]  G. Rollo,et al.  The challenge of nonunion after osteosynthesis of the clavicle: is it a biomechanical or infection problem? , 2017, Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases.

[8]  D. Lorich,et al.  Surgical Technique: Treatment of Distal Humerus Nonunions , 2017, HSS Journal ®.

[9]  A. Caraffa,et al.  Feasibility and Value of Radiographic Union Score Hip Fracture after Treatment with Intramedullary Nail of Stable Hip Fractures , 2016, Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH.

[10]  Y. Tran,et al.  Predictors of return to work following motor vehicle related orthopaedic trauma , 2016, BMC Musculoskeletal Disorders.

[11]  F. Pogliacomi,et al.  Total elbow arthroplasty in distal humeral nonunion: clinical and radiographic evaluation after a minimum follow-up of three years. , 2015, Journal of shoulder and elbow surgery.

[12]  P. Tang,et al.  Infected nonunion of tibia and femur treated by bone transport , 2015, Journal of Orthopaedic Surgery and Research.

[13]  G. Calori,et al.  Validation of the Non-Union Scoring System in 300 long bone non-unions. , 2014, Injury.

[14]  T Bégué,et al.  Articular fractures of the distal humerus. , 2014, Orthopaedics & traumatology, surgery & research : OTSR.

[15]  Amit Bandyopadhyay,et al.  Recent advances in bone tissue engineering scaffolds. , 2012, Trends in biotechnology.

[16]  B. Morrey,et al.  Approaches for elbow arthroplasty: how to handle the triceps. , 2011, Journal of shoulder and elbow surgery.

[17]  C. Allende,et al.  Post-traumatic distal humerus non-union , 2009, International Orthopaedics.

[18]  P. Kloen,et al.  Open Reduction and Internal Fixation of Delayed Unions and Nonunions of Fractures of the Distal Part of the Humerus , 2003, The Journal of bone and joint surgery. American volume.

[19]  R. Simonis,et al.  Use of the coventry infant hip screw in the treatment of nonunion of fractures of the distal humerus. , 2003, The Journal of bone and joint surgery. British volume.

[20]  D. Paley,et al.  Ilizarov treatment of tibial nonunions with bone loss. , 1989, Clinical orthopaedics and related research.