Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress

[1]  E. Coffey.  Nuclear and cytosolic JNK signalling in neurons , 2014, Nature Reviews Neuroscience.

[2]  M. Mattson,et al.  Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke , 2014, Neurobiology of Disease.

[3]  L. Ittner,et al.  ERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke , 2013, Journal of neural transmission.

[4]  E. Kimura,et al.  Notch pathway is activated by MAPK signaling and influences papillary thyroid cancer proliferation. , 2013, Translational oncology.

[5]  W. Xia,et al.  Neuronal Apoptosis and Synaptic Density in the Dentate Gyrus of Ischemic Rats’ Response to Chronic Mild Stress and the Effects of Notch Signaling , 2012, PloS one.

[6]  M. Dallman,et al.  Inflammatory Stimuli Cytokine Responses of Dendritic Cells to Noncanonical Notch Signaling Modulates , 2012 .

[7]  S. Artavanis-Tsakonas,et al.  Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila , 2012, The EMBO journal.

[8]  T. Dang,et al.  γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer , 2012, British Journal of Cancer.

[9]  C. Blobel,et al.  Notch-RBP-J Signaling Regulates IRF8 to Promote Inflammatory Macrophage Polarization , 2012, Nature Immunology.

[10]  Yong-jun Wang,et al.  DAPT protects brain against cerebral ischemia by down-regulating the expression of Notch 1 and Nuclear factor kappa B in rats , 2012, Neurological Sciences.

[11]  C. Meijer,et al.  The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations , 2012, Cellular Oncology.

[12]  T. Arumugam,et al.  Notch Activation Enhances the Microglia-Mediated Inflammatory Response Associated With Focal Cerebral Ischemia , 2011, Stroke.

[13]  Sung-Chun Tang,et al.  Evidence that γ-Secretase-Mediated Notch Signaling Induces Neuronal Cell Death via the Nuclear Factor-κB-Bcl-2-Interacting Mediator of Cell Death Pathway in Ischemic Stroke , 2011, Molecular Pharmacology.

[14]  M. Zawadzka,et al.  Prolonged activation of ERK triggers glutamate‐induced apoptosis of astrocytes: neuroprotective effect of FK506 , 2010, Journal of neurochemistry.

[15]  L. Edvinsson,et al.  Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway , 2010, Journal of Neuroinflammation.

[16]  L. Lau,et al.  Ischemia activates JNK/c‐Jun/AP‐1 pathway to up‐regulate 14‐3‐3γ in astrocyte , 2009, Journal of neurochemistry.

[17]  M. Mattson,et al.  Notch: from neural development to neurological disorders , 2008, Journal of neurochemistry.

[18]  M. Mattson,et al.  Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal , 2008, Experimental Neurology.

[19]  G. Steinberg,et al.  Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke , 2008, Journal of neuroscience research.

[20]  M. Mattson,et al.  Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits , 2007, Proceedings of the National Academy of Sciences.

[21]  A. Edwards,et al.  Deletion of the c-Jun N-terminal Kinase 3 Gene Protects Neonatal Mice against Cerebral Hypoxic—Ischaemic Injury , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[22]  E. Nishida,et al.  Notch Signaling Suppresses p38 MAPK Activity via Induction of MKP-1 in Myogenesis* , 2007, Journal of Biological Chemistry.

[23]  L. L. Reed,et al.  Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells , 2006, Laboratory Investigation.

[24]  M. Mattson,et al.  Gamma secretase–mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke , 2006, Nature Medicine.

[25]  H. Axelson,et al.  Regulation of the Notch target gene Hes-1 by TGFalpha induced Ras/MAPK signaling in human neuroblastoma cells. , 2005, Experimental cell research.

[26]  Guo-Yuan Yang,et al.  Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia , 2004, Brain Research.

[27]  Cheng Song,et al.  β‐Amyloid peptide induces formation of actin stress fibers through p38 mitogen‐activated protein kinase , 2002 .

[28]  Cheng Song,et al.  beta-Amyloid peptide induces formation of actin stress fibers through p38 mitogen-activated protein kinase. , 2002, Journal of neurochemistry.

[29]  M. Ingelman-Sundberg,et al.  Neuroprotective Agent Chlomethiazole Attenuates c-fos, c-jun, and AP-1 Activation through Inhibition of p38 MAP Kinase , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[30]  A. Reith,et al.  Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat. , 2000, Brain research. Molecular brain research.

[31]  I. Mook‐Jung,et al.  Presenilin 1 mediates protein kinase C dependent α-secretase derived amyloid precursor protein secretion and mitogen-activated protein kinase activation in presenilin 1 transfected human embryonic kidney 293 cell , 1999, Neuroscience Letters.