Dynamics of nuclear export of pre-ribosomal subunits revealed by high-speed single-molecule microscopy in live cells

[1]  Samuel L. Junod,et al.  Obtaining 3D super-resolution images by utilizing rotationally symmetric structures and 2D-to-3D transformation , 2023, Computational and structural biotechnology journal.

[2]  Alex D. Herbert,et al.  GDSC SMLM: Single-molecule localisation microscopy software for ImageJ , 2022, Wellcome open research.

[3]  Weidong Yang,et al.  Spelling out the roles of individual nucleoporins in nuclear export of mRNA , 2022, Nucleus.

[4]  Y. Chook,et al.  Karyopherin-mediated nucleocytoplasmic transport , 2022, Nature Reviews Molecular Cell Biology.

[5]  M. Dasso,et al.  Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore , 2021, Proceedings of the National Academy of Sciences.

[6]  U. Kutay,et al.  Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time , 2021, Nature Communications.

[7]  M. Rout,et al.  One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex. , 2021, Trends in biochemical sciences.

[8]  Weidong Yang,et al.  High-speed super-resolution imaging of rotationally symmetric structures using SPEED microscopy and 2D-to-3D transformation , 2020, Nature Protocols.

[9]  M. Dong,et al.  Structural snapshots of human pre-60S ribosomal particles before and after nuclear export , 2020, Nature Communications.

[10]  Weidong Yang,et al.  Nucleocytoplasmic transport of intrinsically disordered proteins studied by high‐speed super‐resolution microscopy , 2020, Protein science : a publication of the Protein Society.

[11]  E. C. Schirmer,et al.  Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins , 2019, International journal of molecular sciences.

[12]  E. Lemke,et al.  Molecular determinants of large cargo transport into the nucleus , 2019, bioRxiv.

[13]  M. Bohnsack,et al.  Uncovering the assembly pathway of human ribosomes and its emerging links to disease , 2019, The EMBO journal.

[14]  J. Dauxois,et al.  The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography , 2019, Nature Communications.

[15]  Damian Szklarczyk,et al.  STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets , 2018, Nucleic Acids Res..

[16]  Jan Gorodkin,et al.  Cytoscape stringApp: Network analysis and visualization of proteomics data , 2018, bioRxiv.

[17]  N. Samadi,et al.  The roles of moonlight ribosomal proteins in the development of human cancers , 2018, Journal of cellular physiology.

[18]  Weidong Yang,et al.  Nuclear export of mRNA molecules studied by SPEED microscopy , 2018, Methods.

[19]  A. Hoelz,et al.  Structural and functional analysis of mRNA export regulation by the nuclear pore complex , 2018, Nature Communications.

[20]  Wangxi Luo,et al.  Nuclear Transport and Accumulation of Smad Proteins Studied by Single-Molecule Microscopy. , 2018, Biophysical journal.

[21]  Roderick Y. H. Lim,et al.  Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium , 2017, Scientific Reports.

[22]  V. G. Panse,et al.  Eukaryotic ribosome assembly, transport and quality control , 2017, Nature Structural &Molecular Biology.

[23]  A. Astegno,et al.  Determination of Hydrodynamic Radius of Proteins by Size Exclusion Chromatography. , 2017, Bio-protocol.

[24]  B. Greber Mechanistic insight into eukaryotic 60S ribosomal subunit biogenesis by cryo-electron microscopy , 2016, RNA.

[25]  Weidong Yang,et al.  Super-resolution 3D tomography of interactions and competition in the nuclear pore complex , 2016, Nature Structural &Molecular Biology.

[26]  Weidong Yang,et al.  Super-resolution imaging of nuclear import of adeno-associated virus in live cells , 2015, Molecular therapy. Methods & clinical development.

[27]  J. Woolford,et al.  Functions of ribosomal proteins in assembly of eukaryotic ribosomes in vivo. , 2015, Annual review of biochemistry.

[28]  Jimin Pei,et al.  LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins , 2015, Bioinform..

[29]  E. Hurt,et al.  NTF2-like domain of Tap plays a critical role in cargo mRNA recognition and export , 2015, Nucleic acids research.

[30]  Weidong Yang,et al.  Role of Molecular Charge in Nucleocytoplasmic Transport , 2014, PloS one.

[31]  A. Zilman,et al.  Large cargo transport by nuclear pores: implications for the spatial organization of FG‐nucleoporins , 2013, The EMBO journal.

[32]  N. Walter,et al.  High-resolution three-dimensional mapping of mRNA export through the nuclear pore , 2013, Nature Communications.

[33]  Weidong Yang Distinct, but not completely separate spatial transport routes in the nuclear pore complex , 2013, Nucleus.

[34]  Daniel N. Wilson,et al.  Structures of the human and Drosophila 80S ribosome , 2013, Nature.

[35]  D. Görlich,et al.  Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes , 2012, The EMBO journal.

[36]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[37]  Weidong Yang,et al.  Self-regulated viscous channel in the nuclear pore complex , 2012, Proceedings of the National Academy of Sciences.

[38]  S. Musser,et al.  Single molecule studies of nucleocytoplasmic transport. , 2011, Biochimica et biophysica acta.

[39]  C. Dekker,et al.  Single-molecule transport across an individual biomimetic nuclear pore complex. , 2011, Nature nanotechnology.

[40]  André Hoelz,et al.  The structure of the nuclear pore complex. , 2011, Annual review of biochemistry.

[41]  Constance Jeffery,et al.  Moonlighting proteins , 2010, Genome Biology.

[42]  Peter Horvath,et al.  A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export , 2010, PLoS biology.

[43]  R. Singer,et al.  In Vivo Imaging of Labelled Endogenous β-actin mRNA During Nucleocytoplasmic Transport , 2010, Nature.

[44]  G. Fichant,et al.  Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits , 2010, The Journal of cell biology.

[45]  R. Kehlenbach,et al.  The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport. , 2010, Trends in cell biology.

[46]  Weidong Yang,et al.  Three-dimensional distribution of transient interactions in the nuclear pore complex obtained from single-molecule snapshots , 2010, Proceedings of the National Academy of Sciences.

[47]  Ulrike Kutay,et al.  Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2 , 2009, The Journal of cell biology.

[48]  Arlen W. Johnson,et al.  Reengineering ribosome export. , 2009, Molecular biology of the cell.

[49]  P. Pandolfi,et al.  Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome , 2008, Molecular and Cellular Biology.

[50]  Ed Hurt,et al.  Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2. , 2007, Molecular cell.

[51]  P. Zobel-Thropp,et al.  Ltv1 Is Required for Efficient Nuclear Export of the Ribosomal Small Subunit in Saccharomyces cerevisiae , 2006, Genetics.

[52]  Pierre-Emmanuel Gleizes,et al.  Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. , 2005, Molecular cell.

[53]  Valérie Choesmel,et al.  Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells , 2005, The EMBO journal.

[54]  J. Ellenberg,et al.  Mapping the dynamic organization of the nuclear pore complex inside single living cells , 2004, Nature Cell Biology.

[55]  J. Gelles,et al.  Imaging of single-molecule translocation through nuclear pore complexes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[56]  T. Freeman,et al.  Investigation Into the use of C- and N-terminal GFP Fusion Proteins for Subcellular Localization Studies Using Reverse Transfection Microarrays , 2004, Comparative and functional genomics.

[57]  Søren Brunak,et al.  Analysis and prediction of leucine-rich nuclear export signals. , 2004, Protein engineering, design & selection : PEDS.

[58]  David Tollervey,et al.  A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits. , 2004, Genes & development.

[59]  A. Helenius,et al.  Nuclear import of hepatitis B virus capsids and release of the viral genome , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[60]  D. Peabody A Viral Platform for Chemical Modification and Multivalent Display , 2003, Journal of nanobiotechnology.

[61]  U. Kutay,et al.  Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway , 2003, Journal of Cell Science.

[62]  S. R. Wente,et al.  Peering through the pore: nuclear pore complex structure, assembly, and function. , 2003, Developmental cell.

[63]  Arlen W. Johnson,et al.  Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates , 2003, The EMBO journal.

[64]  E. Petfalski,et al.  The path from nucleolar 90S to cytoplasmic 40S pre‐ribosomes , 2003, The EMBO journal.

[65]  V. Uversky,et al.  Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[66]  D. Tollervey,et al.  Nuclear Export of 60S Ribosomal Subunits Depends on Xpo1p and Requires a Nuclear Export Sequence-Containing Factor, Nmd3p, That Associates with the Large Subunit Protein Rpl10p , 2001, Molecular and Cellular Biology.

[67]  K Ribbeck,et al.  Kinetic analysis of translocation through nuclear pore complexes , 2001, The EMBO journal.

[68]  Arlen W. Johnson,et al.  Nmd3p Is a Crm1p-Dependent Adapter Protein for Nuclear Export of the Large Ribosomal Subunit , 2000, The Journal of cell biology.

[69]  Ed Hurt,et al.  Binding of the Mex67p/Mtr2p Heterodimer to Fxfg, Glfg, and Fg Repeat Nucleoporins Is Essential for Nuclear mRNA Export , 2000, The Journal of cell biology.

[70]  A. Podtelejnikov,et al.  The Mex67p‐mediated nuclear mRNA export pathway is conserved from yeast to human , 1999, The EMBO journal.

[71]  P. Silver,et al.  A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[72]  Minoru Yoshida,et al.  CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals , 1997, Cell.

[73]  Karsten Weis,et al.  Exportin 1 (Crm1p) Is an Essential Nuclear Export Factor , 1997, Cell.

[74]  T. Kues,et al.  Nuclear transport of single molecules: dwell times at the nuclear pore complex , 2021 .

[75]  Weidong Yang,et al.  Structure and Function of the Nuclear Pore Complex Revealed by High-Resolution Fluorescence Microscopy , 2018 .

[76]  R. Beckmann,et al.  Visualizing late states of human 40S ribosomal subunit maturation , 2018, Nature.

[77]  Tobias Pietzsch,et al.  Fiji:anopen-sourceplatformfor biological-imageanalysis , 2012 .

[78]  U. Kutay,et al.  Transport between the cell nucleus and the cytoplasm. , 1999, Annual review of cell and developmental biology.