The emergence of the uniquely human α7 nicotinic acetylcholine receptor gene and its roles in inflammation.
暂无分享,去创建一个
[1] G. Bergström,et al. Polymorphisms in alpha 7 nicotinic acetylcholine receptor gene, CHRNA7, and its partially duplicated gene, CHRFAM7A, associate with increased inflammatory response in human peripheral mononuclear cells , 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[2] F. Rieux-Laucat,et al. Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients , 2021, Scientific Reports.
[3] Liang Gao,et al. CHRFAM7A Overexpression Attenuates Cerebral Ischemia-Reperfusion Injury via Inhibiting Microglia Pyroptosis Mediated by the NLRP3/Caspase-1 pathway , 2021, Inflammation.
[4] A. Chávez-Reyes,et al. The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release , 2021, The Journal of biological chemistry.
[5] K. Szigeti,et al. iPSC-Derived Microglia for Modeling Human-Specific DAMP and PAMP Responses in the Context of Alzheimer’s Disease , 2020, International journal of molecular sciences.
[6] Chenliang Deng,et al. Human-specific gene CHRFAM7A mediates M2 macrophage polarization via the Notch pathway to ameliorate hypertrophic scar formation. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[7] G. Wilding,et al. CHRFAM7A: A human specific fusion gene, accounts for the translational gap for cholinergic strategies in Alzheimer's disease , 2020, EBioMedicine.
[8] B. Baradaran,et al. The dual role of alpha7 nicotinic acetylcholine receptor in inflammation-associated gastrointestinal cancers , 2020, Heliyon.
[9] J. Mikkelsen,et al. Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons. , 2019, Stem cell research.
[10] J. Ecklund,et al. Association of a Functional Polymorphism in the CHRFAM7A Gene with Inflammatory Response Mediators and Neuropathic Pain after Spinal Cord Injury. , 2019, Journal of neurotrauma.
[11] Xitong Dang,et al. Global proteomic profiling of the uniquely human CHRFAM7A gene in transgenic mouse brain. , 2019, Gene.
[12] B. Yard,et al. The Cholinergic Anti-Inflammatory Pathway as a Conceptual Framework to Treat Inflammation-Mediated Renal Injury , 2019, Kidney and Blood Pressure Research.
[13] D. Fornasari,et al. Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway , 2019, Journal of Neuroimmunology.
[14] B. Eliceiri,et al. Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response , 2019, Proceedings of the National Academy of Sciences.
[15] T. Nayak,et al. iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context , 2019, Translational Psychiatry.
[16] B. Eliceiri,et al. CHRFAM7A alters binding to the neuronal alpha-7 nicotinic acetylcholine receptor , 2019, Neuroscience Letters.
[17] Yan Cheng,et al. α7 Nicotinic acetylcholine receptor contributes to the alleviation of lung ischemia-reperfusion injury by transient receptor potential vanilloid type 1 stimulation. , 2018, The Journal of surgical research.
[18] E. Bacchelli,et al. Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment , 2018, European Journal of Human Genetics.
[19] C. Giménez,et al. Interaction of the α7-nicotinic subunit with its human-specific duplicated dupα7 isoform in mammalian cells: Relevance in human inflammatory responses , 2018, The Journal of Biological Chemistry.
[20] K. Szigeti,et al. Copy Number Variations in Adult-onset Neuropsychiatric Diseases , 2018, Current genomics.
[21] C. Bouzat,et al. A human-specific, truncated α7 nicotinic receptor subunit assembles with full-length α7 and forms functional receptors with different stoichiometries , 2018, The Journal of Biological Chemistry.
[22] Tao-yi Yang,et al. The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials , 2017, Acta pharmaceutica Sinica. B.
[23] J. Lasalde-Dominicci,et al. Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder , 2015, Journal of NeuroVirology.
[24] D. Bertrand,et al. Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors , 2015, Pharmacological Reviews.
[25] Robert Freedman,et al. The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function , 2015, Neuropharmacology.
[26] M. Kassiou,et al. The Therapeutic Potential of α7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonists for the Treatment of the Cognitive Deficits Associated with Schizophrenia , 2015, CNS Drugs.
[27] J. Kleinman,et al. CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders. , 2015, The American journal of psychiatry.
[28] R. Coimbra,et al. A Human-Specific α7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression , 2015, Molecular medicine.
[29] B. Eliceiri,et al. CHRFAM7A: a human‐specific α7‐nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[30] R. Coimbra,et al. CHRFAM7A, a human‐specific and partially duplicated α7‐nicotinic acetylcholine receptor gene with the potential to specify a human‐specific inflammatory response to injury , 2015, Journal of leukocyte biology.
[31] J. Romijn,et al. Hematopoietic α7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis , 2015, Journal of thrombosis and haemostasis : JTH.
[32] H. Lester,et al. The Duplicated α7 Subunits Assemble and Form Functional Nicotinic Receptors with the Full-length α7* , 2014, The Journal of Biological Chemistry.
[33] Liping Huang,et al. Ultrasound prevents renal ischemia-reperfusion injury by stimulating the splenic cholinergic anti-inflammatory pathway. , 2013, Journal of the American Society of Nephrology : JASN.
[34] K. Tracey,et al. A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen , 2013, Gut.
[35] Inmaculada Posadas,et al. Send Orders of Reprints at Reprints@benthamscience.net Nicotinic Receptors in Neurodegeneration , 2022 .
[36] T. Shimazu,et al. Electrical Vagus Nerve Stimulation Attenuates Systemic Inflammation and Improves Survival in a Rat Heatstroke Model , 2013, PloS one.
[37] R. Gamelli,et al. Genomic responses in mouse models poorly mimic human inflammatory diseases , 2013, Proceedings of the National Academy of Sciences.
[38] Jason J. Corneveaux,et al. Analysis of Copy Number Variation in Alzheimer’s Disease in a Cohort of Clinically Characterized and Neuropathologically Verified Individuals , 2012, PloS one.
[39] A. Saykin,et al. Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study. , 2012, Current Alzheimer research.
[40] J. Zhan,et al. Protective Effect of PNU-120596, a Selective Alpha7 Nicotinic Acetylcholine Receptor–positive Allosteric Modulator, on Myocardial Ischemia–reperfusion Injury in Rats , 2012, Journal of cardiovascular pharmacology.
[41] S. Bonassi,et al. Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia. , 2012, Current drug targets.
[42] Laura Calvillo,et al. Vagal Stimulation, Through its Nicotinic Action, Limits Infarct Size and the Inflammatory Response to Myocardial Ischemia and Reperfusion , 2011, Journal of cardiovascular pharmacology.
[43] D. Bertrand,et al. The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function. , 2011, Biochemical pharmacology.
[44] C. Gotti,et al. Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS , 2011, Journal of Neuroimmunology.
[45] J. Renart,et al. Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response. , 2011, The Journal of biological chemistry.
[46] Yong-ming Yao,et al. Role of cholinergic anti-inflammatory pathway in regulating host response and its interventional strategy for inflammatory diseases. , 2009, Chinese journal of traumatology = Zhonghua chuang shang za zhi.
[47] S. Christian,et al. A 2-base pair deletion polymorphism in the partial duplication of the α7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia , 2009, Brain Research.
[48] M. Susin,et al. Nicotinic acetylcholine receptor expression and regulation in the rat kidney after ischemia-reperfusion injury. , 2008, American journal of physiology. Renal physiology.
[49] Kevin J. Tracey,et al. Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia , 2008, Proceedings of the National Academy of Sciences.
[50] Valentin A. Pavlov,et al. Modulation of TNF Release by Choline Requires α7 Subunit Nicotinic Acetylcholine Receptor-Mediated Signaling , 2008, Molecular medicine.
[51] T. Wilens,et al. Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: focus on cognition. , 2007, Biochemical pharmacology.
[52] L. Ulloa,et al. The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation , 2007, British journal of pharmacology.
[53] I. Stolerman,et al. Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task , 2006, Psychopharmacology.
[54] D. Collier,et al. Association study of CHRFAM7A copy number and 2bp deletion polymorphisms with schizophrenia and bipolar affective disorder , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[55] V. Pavlov,et al. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis , 2006, The Journal of experimental medicine.
[56] H. Berthoud,et al. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway , 2005, Nature Immunology.
[57] John Sharkey,et al. Nicotine Improves Sustained Attention in Mice: Evidence for Involvement of the α7 Nicotinic Acetylcholine Receptor , 2004, Neuropsychopharmacology.
[58] Hong Wang,et al. The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation , 2003, Molecular medicine.
[59] Kevin J. Tracey,et al. Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation , 2002, Nature.
[60] M. O'Neill,et al. The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration. , 2002, Current drug targets. CNS and neurological disorders.
[61] D. Bertrand,et al. Expression of an α7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes , 2002, Journal of Neuroimmunology.
[62] D. Collier,et al. A 3-Mb map of a large Segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14. , 2002, Genomics.
[63] Y. Gomita,et al. Neuronal nicotinic receptor and psychiatric disorders: functional and behavioral effects of nicotine. , 2002, Japanese journal of pharmacology.
[64] Yan-qing Zhang,et al. Human-specific CHRFAM7A protects against radiotherapy-induced lacrimal gland injury by inhibiting the p38/JNK signalling pathway and oxidative stress. , 2017, International journal of clinical and experimental pathology.
[65] Song Liu,et al. Ordered subset analysis of copy number variation association with age at onset of Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.
[66] P. F. Zabrodskii. [Change in the non-specific anti-infection resistance of the body exposed to cholinergic stimulation]. , 1995, Biulleten' eksperimental'noi biologii i meditsiny.
[67] P. F. Zabrodskii. [Effect of armin on nonspecific resistance factors of the body and on the primary humoral immune response]. , 1987, Farmakologiia i toksikologiia.