Detection of seizures in EEG using subband nonlinear parameters and genetic algorithm

Detection of seizures in EEG can be challenging because of myogenic artifacts and might be time-consuming. In this study, we propose a method using subband nonlinear parameters and genetic algorithm for automatic seizure detection in EEG. In the experiment, the discrete wavelet transform was used to decompose EEG into five subband components. Nonlinear parameters were extracted and employed as the features to train the support vector machine with linear kernel function (SVML) and radial basis function kernel function (SVMRBF) classifiers. A genetic algorithm (GA) was used for selecting the effective feature subset. The seizure detection sensitivities of the SVML and the SVMRBF with GA are 90.8% and 94.0%, respectively. The sensitivity of SVMRBF increases to 95.8% by using GA for weight adjustment. Moreover, the proposed method is capable of discriminating the interictal EEG of epileptic subjects from the normal EEG, which is considered difficult, yet crucial, in clinical services.

[1]  A. E. Eiben,et al.  Introduction to Evolutionary Computing , 2003, Natural Computing Series.

[2]  R. Burton,et al.  Consistency of the Takens estimator for the correlation dimension , 1999 .

[3]  A. Wolf,et al.  Determining Lyapunov exponents from a time series , 1985 .

[4]  Osvaldo A. Rosso,et al.  Wavelet analysis of generalized tonic-clonic epileptic seizures , 2003, Signal Process..

[5]  Hasan Ocak,et al.  Optimal classification of epileptic seizures in EEG using wavelet analysis and genetic algorithm , 2008, Signal Process..

[6]  Pramod P Khargonekar,et al.  Support vector machines for seizure detection in an animal model of chronic epilepsy , 2010, Journal of neural engineering.

[7]  K Lehnertz,et al.  Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: dependence on recording region and brain state. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[8]  Nasser M. Nasrabadi,et al.  Pattern Recognition and Machine Learning , 2006, Technometrics.

[9]  Robert Tibshirani,et al.  The Elements of Statistical Learning: Data Mining, Inference, and Prediction, 2nd Edition , 2001, Springer Series in Statistics.

[10]  Cheng-Lung Huang,et al.  A GA-based feature selection and parameters optimizationfor support vector machines , 2006, Expert Syst. Appl..

[11]  Abdulhamit Subasi,et al.  Application of adaptive neuro-fuzzy inference system for epileptic seizure detection using wavelet feature extraction , 2007, Comput. Biol. Medicine.

[12]  Abdulhamit Subasi Automatic detection of epileptic seizure using dynamic fuzzy neural networks , 2006, Expert Syst. Appl..

[13]  Hojjat Adeli,et al.  Mixed-Band Wavelet-Chaos-Neural Network Methodology for Epilepsy and Epileptic Seizure Detection , 2007, IEEE Transactions on Biomedical Engineering.

[14]  Vladimir N. Vapnik,et al.  The Nature of Statistical Learning Theory , 2000, Statistics for Engineering and Information Science.

[15]  B. Litt,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group. Review Prediction of Epileptic Seizures Are Seizures Predictable? Prediction of Epileptic Seizures , 2022 .

[16]  Daniel Graupe,et al.  A neural-network-based detection of epilepsy , 2004, Neurological research.

[17]  J. Gotman,et al.  Automatic seizure detection in the newborn: methods and initial evaluation. , 1997, Electroencephalography and clinical neurophysiology.

[18]  David G. Stork,et al.  Pattern Classification , 1973 .

[19]  H. Adeli,et al.  Analysis of EEG records in an epileptic patient using wavelet transform , 2003, Journal of Neuroscience Methods.

[20]  H. Kantz,et al.  Nonlinear time series analysis , 1997 .

[21]  C. Elger,et al.  Seizure prediction by non‐linear time series analysis of brain electrical activity , 1998, The European journal of neuroscience.

[22]  Abdulhamit Subasi,et al.  Epileptic seizure detection using dynamic wavelet network , 2005, Expert Syst. Appl..

[23]  L. Cao Practical method for determining the minimum embedding dimension of a scalar time series , 1997 .

[24]  Brian Litt,et al.  One-Class Novelty Detection for Seizure Analysis from Intracranial EEG , 2006, J. Mach. Learn. Res..

[25]  Massimiliano Pontil,et al.  Support Vector Machines for 3D Object Recognition , 1998, IEEE Trans. Pattern Anal. Mach. Intell..

[26]  Stephen J. Elliott,et al.  Efficient estimation of a time-varying dimension parameter and its application to EEG analysis , 2003, IEEE Transactions on Biomedical Engineering.

[27]  Hojjat Adeli,et al.  A Wavelet-Chaos Methodology for Analysis of EEGs and EEG Subbands to Detect Seizure and Epilepsy , 2007, IEEE Transactions on Biomedical Engineering.

[28]  Abdulhamit Subasi,et al.  Classification of EEG signals using neural network and logistic regression , 2005, Comput. Methods Programs Biomed..