Major Complications of Overnight Orthokeratology Lens for Myopic Correction

Orthokeratology adopts reverse geometry rigid gas-permeable contact lenses to alter the corneal shape and hence refractive power. The effect is transient; therefore, the users need to wear the orthokeratology lenses during night time while asleep, so that they can avoid wearing glasses during daytime. The compressive forces of the reverse geometry rigid lenses may disrupt the corneal epithelium and extended overnight wear may potentiate various side effects, such as lens-corneal binding, corneal staining, microbial keratitis, chronic allergic conjunctivitis and lens decentration. In this article, we conducted a systemic review to summarize the major complications associated with orthokeratology lens use and solutions.