In situ T cells in melanoma
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[1] J. Becker,et al. In situ T cell responses against melanoma comprise high numbers of locally expanded T cell clonotypes. , 1999, Journal of immunology.
[2] J. Becker,et al. Predominant expression of Fas (CD95) ligand in metastatic melanoma revealed by longitudinal analysis. , 1999, The Journal of investigative dermatology.
[3] G. Pawelec,et al. T cell immunosenescence in vitro and in vivo , 1999, Experimental Gerontology.
[4] G. Pawelec,et al. Finite lifespans of t cell clones derived from CD34+ human haematopoietic stem cells in vitro , 1999, Experimental Gerontology.
[5] H. Pehamberger,et al. First comparative delineation of the T cell receptor repertoire in primary and multiple subsequent/coexisting metastatic melanoma sites. , 1998, The Journal of investigative dermatology.
[6] D. Mason,et al. A very high level of crossreactivity is an essential feature of the T-cell receptor. , 1998, Immunology today.
[7] J. Sidney,et al. Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses. , 1998, The Journal of clinical investigation.
[8] M. Colombo,et al. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing. , 1998, Journal of immunology.
[9] J. Becker,et al. Activation of preexisting T cell clones by targeted interleukin 2 therapy. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[10] P. Möller,et al. T cell-mediated, IFN-gamma-facilitated rejection of murine B16 melanomas. , 1998, Journal of immunology.
[11] A. Vallejo,et al. Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28- T cells from rheumatoid arthritis patients. , 1998, Journal of immunology.
[12] J. Zeuthen,et al. Melanoma‐associated antigens recognized by cytotoxic T lymphocytes , 1998, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[13] Soldano Ferrone,et al. Different Requirements for Signal Transducer and Activator of Transcription 1α and Interferon Regulatory Factor 1 in the Regulation of Low Molecular Mass Polypeptide 2 and Transporter Associated with Antigen Processing 1 Gene Expression* , 1998, The Journal of Biological Chemistry.
[14] R. Germain,et al. Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells. , 1998, Journal of immunology.
[15] Richard A. Flavell,et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling , 1998, Nature.
[16] Stephen P. Schoenberger,et al. T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions , 1998, Nature.
[17] E. Appella,et al. Peptides derived from self-proteins as partial agonists and antagonists of human CD8+ T-cell clones reactive to melanoma/melanocyte epitope MART1(27-35). , 1998, Cancer research.
[18] C. Figdor,et al. Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL. , 1998, Journal of immunology.
[19] C. Weyand,et al. Functional properties of CD4+CD28− T cells in the aging immune system , 1998, Mechanisms of Ageing and Development.
[20] B. Seliger,et al. Molecular analysis of the HLA-A2 antigen loss by melanoma cells SK-MEL-29.1.22 and SK-MEL-29.1.29. , 1998, Cancer research.
[21] Walker,et al. Down‐regulation of CD28 via Fas (CD95): influence of CD28 on T‐cell apoptosis , 1998, Immunology.
[22] T. Egeland,et al. Demonstration of identical expanded clones within both CD8+ CD28+ and CD8+ CD28− T cell subsets in HIV type 1‐infected individuals , 1998, European journal of immunology.
[23] J. Becker,et al. Immune response against human primary malignant melanoma: a distinct cytokine mRNA profile associated with spontaneous regression. , 1998, Laboratory investigation; a journal of technical methods and pathology.
[24] F. Marincola,et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma , 1998, Nature Medicine.
[25] L. Moretta,et al. Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses. , 1998, Immunology today.
[26] R. Houghten,et al. Probing degeneracy in T-cell recognition using peptide combinatorial libraries. , 1998, Immunology today.
[27] R. Houghten,et al. Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology. , 1998, Journal of immunology.
[28] Dirk Schadendorf,et al. Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells , 1998, Nature Medicine.
[29] S. Steinberg,et al. Heterogeneous expression of melanoma‐associated antigens and HLA‐A2 in metastatic melanoma in vivo , 1998, International journal of cancer.
[30] D. Pardoll,et al. Induction of antigen-specific T cell anergy: An early event in the course of tumor progression. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[31] D. Longo,et al. Changes in Expression of Signal Transduction Proteins in T Lymphocytes of Patients with Leprosy , 1998, Infection and Immunity.
[32] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[33] A. Weiss,et al. Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs. , 1998, Journal of immunology.
[34] T. Mak,et al. Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. , 1997, Immunity.
[35] G. Pawelec,et al. Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? , 1997, Immunology today.
[36] D. Hicklin,et al. β2-Microglobulin gene mutations in human melanoma cells: molecular characterization and implications for immune surveillance , 1997, Melanoma research.
[37] B. Giannotti,et al. In situ expression of transforming growth factor beta is associated with melanoma progression and correlates with Ki67, HLA-DR and beta 3 integrin expression. , 1997, Melanoma research.
[38] P. Walker,et al. TCR analysis reveals significant repertoire selection during in vitro lymphocyte culture. , 1997, International immunology.
[39] A. Weiss,et al. CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites , 1997, Molecular and cellular biology.
[40] G. Halliday,et al. T helper 1 cytokine mRNA is increased in spontaneously regressing primary melanomas. , 1997, The Journal of investigative dermatology.
[41] G. Carcelain,et al. Diversity of the cytotoxic melanoma-specific immune response: some CTL clones recognize autologous fresh tumor cells and not tumor cell lines. , 1997, Journal of immunology.
[42] J. Zeuthen,et al. Expression of transporter associated with antigen processing 1 and 2 (TAP1/2) in malignant melanoma cell lines , 1997, International journal of cancer.
[43] J. Tschopp,et al. Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape , 1996, Science.
[44] S. Matsushita,et al. Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation. , 1996, Journal of immunology.
[45] J. Ceuppens,et al. CD80, CD86 and CD40 Provide Accessory Signals in a Multiple‐Step T‐Cell Activation Model , 1996, Immunological reviews.
[46] J. Bryant,et al. Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. , 1996, The Journal of clinical investigation.
[47] C. Weyand,et al. The Repertoire of CD4+ CD28− T Cells in Rheumatoid Arthritis , 1996, Molecular medicine.
[48] F. Marincola,et al. Identification of epitope mimics recognized by CTL reactive to the melanoma/melanocyte-derived peptide MART-1(27-35) , 1996, The Journal of experimental medicine.
[49] J. Becker,et al. Clonal T cell responses in tumor infiltrating lymphocytes from both regressive and progressive regions of primary human malignant melanoma. , 1996, The Journal of clinical investigation.
[50] Antonio Lanzavecchia,et al. T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds , 1996, Science.
[51] Alexey M. Olovnikov,et al. Telomeres, telomerase, and aging: Origin of the theory , 1996, Experimental Gerontology.
[52] C. Harley,et al. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. , 1996, AIDS.
[53] P. Moss,et al. Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia. , 1996, Blood.
[54] Michael Loran Dustin,et al. Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area , 1996, The Journal of cell biology.
[55] Scott E. Kern,et al. DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.
[56] F. Marincola,et al. Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. , 1996, Journal of the National Cancer Institute.
[57] N. Cascinelli,et al. Tumor regression responses in melanoma patients treated with a peptide encoded by gene MAGES‐3 , 1995, International journal of cancer.
[58] G. Parmiani,et al. Analysis of TCR usage in human tumors: a new tool for assessing tumor-specific immune responses. , 1995, Immunology today.
[59] D. Longo,et al. Alterations in T cell receptor and signal transduction molecules in melanoma patients. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[60] P. Romero,et al. Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1 , 1995, The Journal of experimental medicine.
[61] F. Marincola,et al. Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. , 1995, Immunology today.
[62] G. Pawelec,et al. Long-term culture of monoclonal human T lymphocytes: models for immunosenescence? , 1995, Mechanisms of Ageing and Development.
[63] A. Anichini,et al. Overexpression of the T-cell receptor beta-chain variable region TCRBV14 in HLA-A2-matched primary human melanomas. , 1995, Cancer research.
[64] P. Itin,et al. In situ analysis of transforming growth factor-beta s (TGF-beta 1, TGF-beta 2, TGF-beta 3), and TGF-beta type II receptor expression in malignant melanoma. , 1995, Carcinogenesis.
[65] M. Matsuda,et al. Alterations in the signal‐transducing molecules of T cells and nk cells in colorectal tumor‐infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease , 1995, International journal of cancer.
[66] A. McLean,et al. In vivo estimates of division and death rates of human T lymphocytes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[67] P. Kourilsky,et al. T-cell repertoire diversity and clonal expansions in normal and clinical samples. , 1995, Immunology today.
[68] X. Sastre,et al. Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection , 1995, European journal of immunology.
[69] L. Samelson,et al. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists , 1995, Science.
[70] C. Garbe,et al. Paracrine and autocrine regulation of human melanocyte and melanoma cell growth by transforming growth factor beta in vitro. , 1994, Anticancer research.
[71] S. Rosenberg,et al. Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. , 1994, Cancer research.
[72] J. Becker,et al. Maintenance of clonal anergy by endogenously produced IL-10. , 1994, International immunology.
[73] P. Kourilsky,et al. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. , 1994, Journal of immunology.
[74] S. Narula,et al. Stimulation of Cytolytic Activity by Interleukin‐10 , 1994, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.
[75] G. Carcelain,et al. Direct evidence to support the immunosurveillance concept in a human regressive melanoma. , 1994, The Journal of clinical investigation.
[76] S. Rosenberg,et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. , 1994, JAMA.
[77] P. Hersey,et al. Production of IL‐10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma , 1994, International journal of cancer.
[78] J. Becker,et al. Tumor escape mechanisms from immunosurveillance: induction of unresponsiveness in a specific MHC-restricted CD4+ human T cell clone by the autologous MHC class II+ melanoma. , 1993, International immunology.
[79] G. Carcelain,et al. Evidence for in situ amplification of tumor-specific cytotoxic T lymphocytes in a human regressive melanoma , 1993 .
[80] S. Ferrone,et al. Selective loss of human leukocyte class I allospecificities and staining of melanoma cells by monoclonal antibodies recognizing monomorphic determinants of class I human leukocyte antigens. , 1993, Cancer research.
[81] M. Lotze,et al. Usage of T‐cell receptor Vβ chain genes in fresh and cultured tumor‐infiltrating lymphocytes from human melanoma , 1993 .
[82] A. Mackensen,et al. Analysis of T cell receptor variability in tumor-infiltrating lymphocytes from a human regressive melanoma. Evidence for in situ T cell clonal expansion. , 1993, The Journal of clinical investigation.
[83] K. Keyomarsi,et al. Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells. , 1992, Cancer research.
[84] G. Nicolini,et al. Expansion of Major Histocompatibility Complex-Restricted Antimelanoma Cytotoxic T-Cell Lymphocyte Clones with Identical T-Cell Receptor from Tumor-Infiltrating Lymphocytes , 1992, Journal of immunotherapy : official journal of the Society for Biological Therapy.
[85] W. Clark. Tumour progression and the nature of cancer. , 1991, British journal of cancer.
[86] D. Ruiter,et al. MHC antigens in human melanomas. , 1991, Seminars in cancer biology.
[87] L. Steinman,et al. Predominant expression of T cell receptor V alpha 7 in tumor-infiltrating lymphocytes of uveal melanoma. , 1990, Science.
[88] A. Begovich,et al. Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients , 1990, Nature.
[89] C. Thompson,et al. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. , 1989, Science.
[90] L. Hayflick. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. , 1965, Experimental cell research.
[91] S. Rosenberg,et al. Human melanoma cells do not express Fas (Apo-1/CD95) ligand. , 1999, Cancer research.
[92] L. Lanier. NK cell receptors. , 1998, Annual review of immunology.
[93] F. Marincola,et al. Recognition of melanoma-derived antigens by CTL: possible mechanisms involved in down-regulating anti-tumor T-cell reactivity. , 1998, Critical reviews in immunology.
[94] A. Roberts,et al. Regulation of immune responses by TGF-beta. , 1998, Annual review of immunology.
[95] P. Kourilsky,et al. Tumor-specific immune response: current in vitro analyses may not reflect the in vivo immune status. , 1998, Critical reviews in immunology.
[96] P. Guldberg,et al. Detection and characterization of alpha-beta-T-cell clonality by denaturing gradient gel electrophoresis (DGGE). , 1998, BioTechniques.
[97] Gideon Berke,et al. Killing mechanisms of cytotoxic lymphocytes , 1997, Current opinion in hematology.
[98] R. Perlmutter,et al. Differential signaling by lymphocyte antigen receptors. , 1997, Annual review of immunology.
[99] G. Pawelec,et al. Escape from host-antitumor immunity. , 1997, Critical reviews in oncogenesis.
[100] K. Miyazono,et al. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. , 1997, Nature.
[101] D. Avidandrews,et al. In vivo accumulation of the same anti-melanoma T cell clone in two different metastatic sites , 1997 .
[102] S. Rosenberg,et al. T-cell recognition of self peptides as tumor rejection antigens , 1996, Immunologic research.
[103] J. Schøller,et al. Analysis of T cell receptor alpha beta variability in lymphocytes infiltrating melanoma primary tumours and metastatic lesions. , 1994, Cancer immunology, immunotherapy : CII.
[104] J. Schøller,et al. Preferential usage of T-cell receptor alpha beta variable regions among tumor-infiltrating lymphocytes in primary human malignant melanomas. , 1994, International journal of cancer.
[105] S. Roman-Roman,et al. Analysis of T-cell receptor alpha/beta variability in lymphocytes infiltrating a melanoma metastasis. , 1992, Cancer research.
[106] M. Davis,et al. T cell receptor gene diversity and selection. , 1990, Annual review of biochemistry.
[107] T. Mak,et al. Thymic ontogeny and selection of alpha beta and gamma delta T cells. , 1989, Immunology today.
[108] S. Rosenberg. Immunotherapy of cancer using interleukin 2: current status and future prospects. , 1988, Immunology today.
[109] R. Myers,et al. Detection and localization of single base changes by denaturing gradient gel electrophoresis. , 1987, Methods in enzymology.
[110] T. Mitsudomi,et al. E-mail alerts Sign up to receive free email-alerts related to this article or journal. Reprints and Subscriptions Permissions , 1947 .