Genetic Approaches to Investigate the Role of CREB in Neuronal Plasticity and Memory

[1]  H. Marie,et al.  Viral-mediated expression of a constitutively active form of CREB in the dentate gyrus does not induce abnormally enduring fear memory , 2011, Behavioural Brain Research.

[2]  H. Marie,et al.  Viral-mediated expression of a constitutively active form of cAMP response element binding protein in the dentate gyrus increases long term synaptic plasticity , 2011, Neuroscience.

[3]  M. Barry,et al.  Advances and Future Challenges in Adenoviral Vector Pharmacology and Targeting , 2011, Current gene therapy.

[4]  M. Zhuo,et al.  Upregulation of CREB-Mediated Transcription Enhances Both Short- and Long-Term Memory , 2011, The Journal of Neuroscience.

[5]  Brian R. Lee,et al.  A Silent Synapse-Based Mechanism for Cocaine-Induced Locomotor Sensitization , 2011, The Journal of Neuroscience.

[6]  J. Valero,et al.  The role of CREB signaling in Alzheimer’s disease and other cognitive disorders , 2011, Reviews in the neurosciences.

[7]  E. Kandel,et al.  Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture , 2011, Neuron.

[8]  D. Lie,et al.  CREB in adult neurogenesis – master and partner in the development of adult‐born neurons? , 2011, The European journal of neuroscience.

[9]  S. Kida,et al.  Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze , 2011, Molecular Brain.

[10]  R. Jagasia,et al.  CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis , 2011, Molecular and Cellular Neuroscience.

[11]  K. Obrietan,et al.  CREB: a multifaceted regulator of neuronal plasticity and protection , 2011, Journal of neurochemistry.

[12]  A. Caccamo,et al.  CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease , 2010, Alzheimer's & Dementia.

[13]  C. Lüscher,et al.  Effects of the cell type‐specific ablation of the cAMP‐responsive transcription factor in noradrenergic neurons on locus coeruleus firing and withdrawal behavior after chronic exposure to morphine , 2010, Journal of neurochemistry.

[14]  E. Nestler,et al.  Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons , 2010, Proceedings of the National Academy of Sciences.

[15]  A. Lleó,et al.  β-Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1 , 2010, The Journal of Neuroscience.

[16]  S. Josselyn Continuing the search for the engram: examining the mechanism of fear memories. , 2010, Journal of psychiatry & neuroscience : JPN.

[17]  H. Bokhoven,et al.  Disruption of the epigenetic code: An emerging mechanism in mental retardation , 2010, Neurobiology of Disease.

[18]  P. Frankland,et al.  Dorsal hippocampal CREB is both necessary and sufficient for spatial memory. , 2010, Learning & memory.

[19]  A. Barco,et al.  CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models , 2010, Trends in Neurosciences.

[20]  R. Luján,et al.  Ultrastructural and transcriptional profiling of neuropathological misregulation of CREB function , 2010, Cell Death and Differentiation.

[21]  Jun Noguchi,et al.  Structural dynamics of dendritic spines in memory and cognition , 2010, Trends in Neurosciences.

[22]  Janka Mátrai,et al.  Recent advances in lentiviral vector development and applications. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[23]  R. Brambilla,et al.  Viral vector approaches to modify gene expression in the brain , 2009, Journal of Neuroscience Methods.

[24]  M. López de Armentia,et al.  Inhibition of cAMP response element-binding protein reduces neuronal excitability and plasticity, and triggers neurodegeneration. , 2009, Cerebral cortex.

[25]  Boyoung Lee,et al.  CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington's disease , 2009, Neurobiology of Disease.

[26]  Alcino J. Silva,et al.  Molecular and Cellular Approaches to Memory Allocation in Neural Circuits , 2009, Science.

[27]  J. Arthur,et al.  Generation of a conditional CREB Ser133Ala knockin mouse , 2009, Genesis.

[28]  Alcino J. Silva,et al.  CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala , 2009, Nature Neuroscience.

[29]  F. Gage,et al.  GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus , 2009, The Journal of Neuroscience.

[30]  C. Pittenger,et al.  Inhibition of CREB Activity in the Dorsal Portion of the Striatum Potentiates Behavioral Responses to Drugs of Abuse , 2009, Front. Behav. Neurosci..

[31]  A. Barco,et al.  Inhibition of cAMP Responsive Element Binding Protein in Striatal Neurons Enhances Approach and Avoidance Responses toward Morphine- and Morphine Withdrawal-related Cues , 2009, Front. Behav. Neurosci..

[32]  Bruno Bontempi,et al.  Selective Erasure of a Fear Memory , 2009, Science.

[33]  E. Kandel,et al.  Chronic enhancement of CREB activity in the hippocampus interferes with the retrieval of spatial information. , 2009, Learning & memory.

[34]  M. López de Armentia,et al.  Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual and cued fear memory. , 2009, Learning & memory.

[35]  Boyoung Lee,et al.  The CREB/CRE transcriptional pathway: protection against oxidative stress‐mediated neuronal cell death , 2009, Journal of neurochemistry.

[36]  Hélène Marie,et al.  Viral‐mediated expression of a constitutively active form of CREB in hippocampal neurons increases memory , 2009, Hippocampus.

[37]  Satoshi Kida,et al.  Brain Region-Specific Gene Expression Activation Required for Reconsolidation and Extinction of Contextual Fear Memory , 2009, The Journal of Neuroscience.

[38]  M. Buhot,et al.  Spatial memory in the Morris water maze and activation of cyclic AMP response element-binding (CREB) protein within the mouse hippocampus. , 2008, Learning & memory.

[39]  V. Zachariou,et al.  Adeno‐associated virus‐mediated gene delivery approaches for the treatment of CNS disorders , 2008, Biotechnology journal.

[40]  Jan Rodriguez Parkitna,et al.  The FASEB Journal • Research Communication , 2007 .

[41]  S. Josselyn,et al.  Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear. , 2008, Learning & memory.

[42]  R. Malenka,et al.  CREB Modulates the Functional Output of Nucleus Accumbens Neurons , 2008, Journal of Biological Chemistry.

[43]  R. Neve,et al.  Transfection of mutant CREB in the striatum, but not the hippocampus, impairs long-term memory for response learning , 2008, Neurobiology of Learning and Memory.

[44]  E. Kandel,et al.  cAMP Response Element-Binding Protein-Mediated Gene Expression Increases the Intrinsic Excitability of CA1 Pyramidal Neurons , 2007, The Journal of Neuroscience.

[45]  H. Korf,et al.  The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception. , 2007, Biochemical and biophysical research communications.

[46]  J. Neumaier,et al.  Opposing functions of CREB and MKK1 synergistically regulate the geometry of dendritic spines in visual cortex , 2007, The Journal of comparative neurology.

[47]  R. Parlato,et al.  Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis , 2007, Development.

[48]  Suzanne Schubbert,et al.  Hyperactive Ras in developmental disorders and cancer , 2007, Nature Reviews Cancer.

[49]  R. Neve,et al.  Long-term memory for place learning is facilitated by expression of cAMP response element-binding protein in the dorsal hippocampus. , 2007, Learning & memory.

[50]  Boyoung Lee,et al.  CRE-mediated transcription and COX-2 expression in the pilocarpine model of status epilepticus , 2007, Neurobiology of Disease.

[51]  F. Gage,et al.  Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo , 2006, Nature Protocols.

[52]  F. Tronche,et al.  Survival of DA neurons is independent of CREM upregulation in absence of CREB , 2006, Genesis.

[53]  E. Kandel,et al.  Impaired Bidirectional Synaptic Plasticity and Procedural Memory Formation in Striatum-Specific cAMP Response Element-Binding Protein-Deficient Mice , 2006, The Journal of Neuroscience.

[54]  E. Kandel,et al.  Common molecular mechanisms in explicit and implicit memory , 2006, Journal of neurochemistry.

[55]  G. Aghajanian,et al.  Role of cAMP Response Element-Binding Protein in the Rat Locus Ceruleus: Regulation of Neuronal Activity and Opiate Withdrawal Behaviors , 2006, The Journal of Neuroscience.

[56]  R. Malenka,et al.  CREB modulates excitability of nucleus accumbens neurons , 2006, Nature Neuroscience.

[57]  M. During,et al.  Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[58]  Eric R Kandel,et al.  Capture of the Late Phase of Long-Term Potentiation within and across the Apical and Basilar Dendritic Compartments of CA1 Pyramidal Neurons: Synaptic Tagging Is Compartment Restricted , 2006, The Journal of Neuroscience.

[59]  K. Lundstrom Biology and application of alphaviruses in gene therapy , 2005, Gene Therapy.

[60]  S. Josselyn,et al.  CREB, synapses and memory disorders: past progress and future challenges. , 2005, Current drug targets. CNS and neurological disorders.

[61]  E. Nestler,et al.  Use of herpes virus amplicon vectors to study brain disorders. , 2005, BioTechniques.

[62]  E. Nestler,et al.  The many faces of CREB , 2005, Trends in Neurosciences.

[63]  J. Aggleton,et al.  cAMP Responsive Element-Binding Protein Phosphorylation Is Necessary for Perirhinal Long-Term Potentiation and Recognition Memory , 2005, The Journal of Neuroscience.

[64]  M. Barrot,et al.  Regulation of Drug Reward by cAMP Response Element-Binding Protein: Evidence for Two Functionally Distinct Subregions of the Ventral Tegmental Area , 2005, The Journal of Neuroscience.

[65]  Deanna L. Wallace,et al.  Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[66]  Wade Morishita,et al.  Generation of Silent Synapses by Acute In Vivo Expression of CaMKIV and CREB , 2005, Neuron.

[67]  Greg Q Butcher,et al.  Activity-Dependent Neuroprotection and cAMP Response Element-Binding Protein (CREB): Kinase Coupling, Stimulus Intensity, and Temporal Regulation of CREB Phosphorylation at Serine 133 , 2005, The Journal of Neuroscience.

[68]  F. Crews,et al.  CREB gene transcription factors: role in molecular mechanisms of alcohol and drug addiction. , 2005, Alcoholism, clinical and experimental research.

[69]  J. Blendy,et al.  Alterations in morphine-induced reward, locomotor activity, and thermoregulation in CREB-deficient mice , 2005, Brain Research.

[70]  Eric R. Kandel,et al.  Activated CREB Is Sufficient to Overcome Inhibitors in Myelin and Promote Spinal Axon Regeneration In Vivo , 2004, Neuron.

[71]  K. Prasad,et al.  Regulated expression of VP16CREB in neuroblastoma cells: Analysis of differentiation and apoptosis , 2004, Journal of neuroscience research.

[72]  E. Kandel,et al.  A semi-persistent adult ocular dominance plasticity in visual cortex is stabilized by activated CREB. , 2004, Learning & memory.

[73]  U. Moens,et al.  What turns CREB on? , 2004, Cellular signalling.

[74]  J. Barquinero,et al.  Retroviral vectors: new applications for an old tool , 2004, Gene therapy.

[75]  S. Josselyn,et al.  Inducible repression of CREB function disrupts amygdala-dependent memory , 2004, Neurobiology of Learning and Memory.

[76]  R. Neve,et al.  Effects of cyclic adenosine monophosphate response element binding protein overexpression in the basolateral amygdala on behavioral models of depression and anxiety , 2004, Biological Psychiatry.

[77]  Lorraine W. Lau,et al.  Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[78]  J. Kew,et al.  Adenoviral expression of CREB protects neurons from apoptotic and excitotoxic stress , 2004, Neuroreport.

[79]  H. Orr,et al.  Overexpression of CREB reduces CRE-mediated transcription: behavioral and cellular analyses in transgenic mice , 2004, Molecular and Cellular Neuroscience.

[80]  Pavel Osten,et al.  Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons , 2004, Journal of Neuroscience Methods.

[81]  E. Kandel,et al.  A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[82]  R. Duman,et al.  Activation of cAMP Signaling Facilitates the Morphological Maturation of Newborn Neurons in Adult Hippocampus , 2004, The Journal of Neuroscience.

[83]  A. Orth,et al.  Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[84]  Loren Miraglia,et al.  TORCs: transducers of regulated CREB activity. , 2003, Molecular cell.

[85]  David P. Wolfer,et al.  Does cAMP Response Element-Binding Protein Have a Pivotal Role in Hippocampal Synaptic Plasticity and Hippocampus-Dependent Memory? , 2003, The Journal of Neuroscience.

[86]  R. Bourtchouladze,et al.  Targeting the CREB pathway for memory enhancers , 2003, Nature Reviews Drug Discovery.

[87]  E. Kandel,et al.  CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects , 2003, Expert opinion on therapeutic targets.

[88]  Eric J. Nestler,et al.  Inhibition of cAMP Response Element-Binding Protein or Dynorphin in the Nucleus Accumbens Produces an Antidepressant-Like Effect , 2002, The Journal of Neuroscience.

[89]  D. Ginty,et al.  Function and Regulation of CREB Family Transcription Factors in the Nervous System , 2002, Neuron.

[90]  Rachael L Neve,et al.  CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[91]  Anirvan Ghosh,et al.  Calcium Regulation of Dendritic Growth via CaM Kinase IV and CREB-Mediated Transcription , 2002, Neuron.

[92]  Haining Dai,et al.  Spinal Axon Regeneration Induced by Elevation of Cyclic AMP , 2002, Neuron.

[93]  M. Kelz,et al.  Inducible and brain region-specific CREB transgenic mice. , 2002, Molecular pharmacology.

[94]  D. Ginty,et al.  CREB family transcription factors inhibit neuronal suicide , 2002, Nature Medicine.

[95]  H. Bading,et al.  Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways , 2002, Nature Neuroscience.

[96]  A. Riccio,et al.  Apoptosis, Axonal Growth Defects, and Degeneration of Peripheral Neurons in Mice Lacking CREB , 2002, Neuron.

[97]  Eric R. Kandel,et al.  Reversible Inhibition of CREB/ATF Transcription Factors in Region CA1 of the Dorsal Hippocampus Disrupts Hippocampus-Dependent Spatial Memory , 2002, Neuron.

[98]  I. Lucki,et al.  cAMP Response Element-Binding Protein Is Essential for the Upregulation of Brain-Derived Neurotrophic Factor Transcription, But Not the Behavioral or Endocrine Responses to Antidepressant Drugs , 2002, The Journal of Neuroscience.

[99]  T. Soderling,et al.  Phosphorylation of CBP Mediates Transcriptional Activation by Neural Activity and CaM Kinase IV , 2002, Neuron.

[100]  U. Schibler,et al.  Phosphorylation of CREB Ser142 Regulates Light-Induced Phase Shifts of the Circadian Clock , 2002, Neuron.

[101]  Satoshi Kida,et al.  CREB required for the stability of new and reactivated fear memories , 2002, Nature Neuroscience.

[102]  A. S. Ramoa,et al.  cAMP/Ca2+ Response Element-Binding Protein Function Is Essential for Ocular Dominance Plasticity , 2002, The Journal of Neuroscience.

[103]  Eric R. Kandel,et al.  Expression of Constitutively Active CREB Protein Facilitates the Late Phase of Long-Term Potentiation by Enhancing Synaptic Capture , 2002, Cell.

[104]  E. Kandel The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses , 2001, Science.

[105]  E. Nestler,et al.  Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens , 2001, The Journal of Neuroscience.

[106]  M. Dragunow,et al.  Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes , 2001, Gene Therapy.

[107]  T. Lemberger,et al.  A CamKIIα iCre BAC allows brain‐specific gene inactivation , 2001 .

[108]  Alcino J. Silva,et al.  The CRE/CREB Pathway Is Transiently Expressed in Thalamic Circuit Development and Contributes to Refinement of Retinogeniculate Axons , 2001, Neuron.

[109]  Marc Montminy,et al.  Transcriptional regulation by the phosphorylation-dependent factor CREB , 2001, Nature Reviews Molecular Cell Biology.

[110]  Sheena A. Josselyn,et al.  Long-Term Memory Is Facilitated by cAMP Response Element-Binding Protein Overexpression in the Amygdala , 2001, The Journal of Neuroscience.

[111]  F. Wondisford,et al.  CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box. , 2001, Molecular cell.

[112]  Alcino J. Silva,et al.  Blockade of cyclic AMP‐responsive element DNA binding in the brain of CREBΔ/α mutant mice , 2000, Neuroreport.

[113]  W Zieglgänsberger,et al.  Synaptic plasticity in the basolateral amygdala in transgenic mice expressing dominant‐negative cAMP response element‐binding protein (CREB) in forebrain , 2000, The European journal of neuroscience.

[114]  Alison L. Barth,et al.  Upregulation of cAMP Response Element-Mediated Gene Expression during Experience-Dependent Plasticity in Adult Neocortex , 2000, The Journal of Neuroscience.

[115]  M. Montminy,et al.  Characterization of a CREB Gain-of-Function Mutant with Constitutive Transcriptional Activity In Vivo , 2000, Molecular and Cellular Biology.

[116]  T. Laverty,et al.  Response of Schwann cells to action potentials in development. , 2000, Science.

[117]  J. Craig,et al.  Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation , 2000, Molecular and Cellular Biology.

[118]  M. Dragunow,et al.  Is CREB a key to neuronal survival? , 2000, Trends in Neurosciences.

[119]  C. M. Davenport,et al.  Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. , 1999, Science.

[120]  E. Kandel,et al.  Nitric Oxide Signaling Contributes to Late-Phase LTP and CREB Phosphorylation in the Hippocampus , 1999, The Journal of Neuroscience.

[121]  S. R. Datta,et al.  Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. , 1999, Science.

[122]  E. Kandel,et al.  A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis , 1999, Cell.

[123]  M. Bear,et al.  A molecular correlate of memory and amnesia in the hippocampus , 1999, Nature Neuroscience.

[124]  G. Devries,et al.  Phosphorylation of CREB in axon‐induced Schwann cell proliferation , 1999, Journal of neuroscience research.

[125]  N. Hiroi,et al.  Regulation of cocaine reward by CREB. , 1998, Science.

[126]  D. Storm,et al.  Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning , 1998, Nature Neuroscience.

[127]  M. Poo,et al.  Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. , 1998, Science.

[128]  U. Frey,et al.  Deficits in memory tasks of mice with CREB mutations depend on gene dosage. , 1998, Learning & memory.

[129]  M. Kelz,et al.  Transgenic animals with inducible, targeted gene expression in brain. , 1998, Molecular pharmacology.

[130]  P. Gass,et al.  Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[131]  Howard Eichenbaum,et al.  Abnormal hippocampal spatial representation in aCaMKIIT286A and CREBaD-mice , 1998 .

[132]  D. Ginty,et al.  A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos , 1998, Molecular and Cellular Biology.

[133]  M. Olive,et al.  A Dominant Negative to Activation Protein-1 (AP1) That Abolishes DNA Binding and Inhibits Oncogenesis* , 1997, The Journal of Biological Chemistry.

[134]  J L McGaugh,et al.  Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[135]  M. Segal,et al.  Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[136]  Alcino J. Silva,et al.  Spaced training induces normal long-term memory in CREB mutant mice , 1997, Current Biology.

[137]  K. Deisseroth,et al.  CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression , 1996, Cell.

[138]  E. Kandel,et al.  Control of Memory Formation Through Regulated Expression of a CaMKII Transgene , 1996, Science.

[139]  P. Gass,et al.  Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB , 1996, Science.

[140]  E. Villacres,et al.  Induction of CRE-Mediated Gene Expression by Stimuli That Generate Long-Lasting LTP in Area CA1 of the Hippocampus , 1996, Neuron.

[141]  W. Schmid,et al.  Targeting of the CREB gene leads to up‐regulation of a novel CREB mRNA isoform. , 1996, The EMBO journal.

[142]  M. Gossen,et al.  Transcriptional activation by tetracyclines in mammalian cells. , 1995, Science.

[143]  W. Schmid,et al.  Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene , 1995, Brain Research.

[144]  Alcino J. Silva,et al.  Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein , 1994, Cell.

[145]  Wolfgang Schmid,et al.  Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[146]  R. Brennan,et al.  Engineered leucine zippers show that hemiphosphorylated CREB complexes are transcriptionally active. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[147]  M. Gossen,et al.  Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[148]  R. Goodman,et al.  A dominant repressor of cyclic adenosine 3',5'-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo. , 1992, Molecular endocrinology.

[149]  Eric R. Kandel,et al.  Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation , 1990, Nature.

[150]  Y. Dudai,et al.  Abnormal activity of adenylate cyclase in the Drosophila memory mutant rutabaga , 1983, Neuroscience Letters.

[151]  E R Kandel,et al.  Synaptic facilitation and behavioral sensitization in Aplysia: possible role of serotonin and cyclic AMP. , 1976, Science.

[152]  S. Josselyn,et al.  4.27 – Transcription Regulation of Memory: CREB, CaMKIV, Fos/Jun, CBP, and SRF , 2008 .

[153]  E. Kandel,et al.  CREB-Dependent Transcription and Synaptic Plasticity , 2008 .

[154]  J. Byrne Learning and memory : a comprehensive reference , 2008 .

[155]  S. Dudek Transcriptional regulation by neuronal activity : to the nucleus and back , 2007 .

[156]  R. Neve,et al.  Hippocampal overexpression of mutant creb blocks long-term, but not short-term memory for a socially transmitted food preference. , 2005, Learning & memory.

[157]  C. McClung,et al.  Regulation of gene expression and cocaine reward by CREB and DeltaFosB. , 2003, Nature neuroscience.

[158]  Ted Abel,et al.  Behavioral analysis of CREB αΔ mutation on a B6/129 F1 hybrid background , 2002 .

[159]  Wolfgang Schmid,et al.  Disruption of CREB function in brain leads to neurodegeneration , 2002, Nature Genetics.

[160]  I. Lucki,et al.  Behavioral analysis of CREB alphadelta mutation on a B6/129 F1 hybrid background. , 2002, Hippocampus.

[161]  W. Quinn,et al.  Flies, genes, and learning. , 2001, Annual review of neuroscience.

[162]  E. Nestler,et al.  Molecular basis of long-term plasticity underlying addiction , 2001, Nature Reviews Neuroscience.

[163]  K. Lundstrom,et al.  Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells , 2001, Histochemistry and Cell Biology.

[164]  S. J. Martin,et al.  Synaptic plasticity and memory: an evaluation of the hypothesis. , 2000, Annual review of neuroscience.

[165]  Alcino J. Silva,et al.  Long‐term memory underlying hippocampus‐dependent social recognition in mice , 2000, Hippocampus.

[166]  M. Filbin,et al.  Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism , 1999, Neuron.

[167]  M. Stryker,et al.  CRE-Mediated Gene Transcription in Neocortical Neuronal Plasticity during the Developmental Critical Period , 1999, Neuron.

[168]  H Eichenbaum,et al.  Abnormal hippocampal spatial representations in alphaCaMKIIT286A and CREBalphaDelta- mice. , 1998, Science.

[169]  Alcino J. Silva,et al.  CREB and memory. , 1998, Annual review of neuroscience.

[170]  M. Montminy,et al.  Transcriptional regulation by cyclic AMP. , 1997, Annual review of biochemistry.

[171]  K. Deisseroth,et al.  Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity , 1996, Neuron.

[172]  Ronald L. Davis,et al.  Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster , 1981, Nature.

[173]  Alcino J. Silva,et al.  Supporting Online Material Materials and Methods Som Text Figs. S1 to S5 Tables S1 to S3 References Neuronal Competition and Selection during Memory Formation , 2022 .