论文信息 - Capturing resting T cells: the perils of PLL

Capturing resting T cells: the perils of PLL

Supported by a Royal Society University Research Fellowship (UF120277 to S.F.L.) and Research Professorship (RP150066 to D.K.); the EPSRC (EP/L027631/1 to A.P.,); the Wellcome Trust (098274/Z/12/Z to S.J.D., and WT101609MA to R.A.F.); PA Cephalosporin Fund (C.E.); the Wolfson Imaging Centre Oxford (funded by the Wolfson Foundation and Wellcome Trust; 104924/14/Z/14); the Micron Advanced BioImaging Unit (Wellcome Trust Strategic Award 091911); the Medical Research Council (MC_UU_12010/Unit Programmes G0902418 and MC_UU_12025); an MRC/BBSRC/EPSRC award (MR/K01577X/1); and a Marie Sklodowska-Curie Intra-European grant (707348 to I.U.).

[1] William J. Fitzgerald,et al. Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells , 2007, Proceedings of the National Academy of Sciences.

[2] Michael L. Dustin,et al. JCB_200809136 521..534 , 2009 .

[3] Mark M Davis,et al. TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation , 2010, Nature Immunology.

[4] N. Hogg,et al. The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes. , 2011, Blood.

[5] Suliana Manley,et al. Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor. , 2011, Immunity.

[6] Dylan M Owen,et al. Superresolution Microscopy Reveals Nanometer-Scale Reorganization of Inhibitory Natural Killer Cell Receptors upon Activation of NKG2D , 2013, Science Signaling.

[7] Katharina Gaus,et al. Conformational states of the kinase Lck regulate clustering in early T cell signaling , 2012, Nature Immunology.

[8] O. Ronneberger,et al. B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation , 2015, Science Signaling.

[9] D. Klenerman,et al. Initiation of T cell signaling by CD45 segregation at ‘close-contacts’ , 2016, Nature Immunology.

[10] Abhinav Mehta,et al. Stimuli-responsive hydrogels in drug delivery and tissue engineering , 2016, Drug delivery.