Reviews of Physiology, Biochemistry and Pharmacology Vol. 170

[1]  M. Beckmann,et al.  Differential effects of low birthweight and intrauterine growth restriction on umbilical cord blood insulin‐like growth factor concentrations , 2015, Clinical endocrinology.

[2]  F. Bezanilla,et al.  Resting state of the human proton channel dimer in a lipid bilayer , 2015, Proceedings of the National Academy of Sciences.

[3]  Steve Cunningham,et al.  Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial , 2015 .

[4]  Mohamed Chahine,et al.  Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy , 2015, Channels.

[5]  M. Freemark Placental hormones and the control of fetal growth , 2015, International Journal of Pediatric Endocrinology.

[6]  M. Bagnat,et al.  Loss of cftr function leads to pancreatic destruction in larval zebrafish. , 2015, Developmental biology.

[7]  D. Meyerholz,et al.  Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology. , 2015, American journal of physiology. Gastrointestinal and liver physiology.

[8]  D. Julius,et al.  Structure of the TRPA1 ion channel suggests regulatory mechanisms , 2015, Nature.

[9]  A. Marchand,et al.  Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release , 2015, Proceedings of the National Academy of Sciences.

[10]  E. Isacoff,et al.  A specialized molecular motion opens the Hv1 voltage-gated proton channel , 2015, Nature Structural &Molecular Biology.

[11]  M. Zaccolo,et al.  Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis. , 2015, Gastroenterology.

[12]  M. Klein,et al.  Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy , 2015, The Journal of general physiology.

[13]  J. Long,et al.  Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy , 2014, Journal of diabetes investigation.

[14]  P. Hiatt,et al.  Efficacy and safety of ivacaftor in patients with cystic fibrosis and a non-G551D gating mutation. , 2014, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[15]  C. Gaudio,et al.  Cardiac involvement in chronic progressive external ophthalmoplegia , 2014, Journal of the Neurological Sciences.

[16]  L. Naehrlich,et al.  Intestinal current measurement versus nasal potential difference measurements for diagnosis of cystic fibrosis: a case–control study , 2014, BMC Pulmonary Medicine.

[17]  M. Tarnopolsky,et al.  Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice. , 2014, Free radical biology & medicine.

[18]  W. Catterall,et al.  Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac , 2014, The Journal of general physiology.

[19]  S. Cannon,et al.  Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis , 2014, The Journal of general physiology.

[20]  S. Peltz,et al.  Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. , 2014, The Lancet. Respiratory medicine.

[21]  G. Lukács,et al.  Protein homeostasis at the plasma membrane. , 2014, Physiology.

[22]  Ivet Bahar,et al.  Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis , 2014, PLoS genetics.

[23]  G. Nuovo,et al.  Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels , 2014, Respiratory Research.

[24]  Jin Han,et al.  NecroX‐5 suppresses sodium nitroprusside‐induced cardiac cell death through inhibition of JNK and caspase‐3 activation , 2014, Cell biology international.

[25]  G. Haines,et al.  Matricellular protein CCN1 (CYR61) expression is associated with high-grade ductal carcinoma in situ. , 2014, Human pathology.

[26]  F. Bezanilla,et al.  Moving gating charges through the gating pore in a Kv channel voltage sensor , 2014, Proceedings of the National Academy of Sciences.

[27]  J. Rahman,et al.  Mitochondrial DNA-Associated Leigh Syndrome and NARP , 2014 .

[28]  M. Ferjani,et al.  Myocardial ischemic conditioning: Physiological aspects and clinical applications in cardiac surgery. , 2014, Journal of the Saudi Heart Association.

[29]  A. Logan,et al.  In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice , 2014, Aging cell.

[30]  M. Dransfield,et al.  Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis. , 2014, American journal of respiratory cell and molecular biology.

[31]  Mohamed Chahine,et al.  Biophysics, pathophysiology, and pharmacology of ion channel gating pores , 2014, Front. Pharmacol..

[32]  R. Vennekens,et al.  Opening of an alternative ion permeation pathway in a nociceptor TRP channel. , 2014, Nature chemical biology.

[33]  P. Hegyi,et al.  The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice* , 2014, Critical care medicine.

[34]  F. Lehmann-Horn,et al.  NaV1.4 mutations cause hypokalaemic periodic paralysis by disrupting IIIS4 movement during recovery , 2014, Brain : a journal of neurology.

[35]  M. Dransfield,et al.  Impact of heterozygote CFTR Mutations in COPD patients with Chronic Bronchitis , 2014, Respiratory Research.

[36]  J. Zweier,et al.  Cardiac Mitochondria and Reactive Oxygen Species Generation , 2014, Circulation research.

[37]  P. Burgel,et al.  p.Arg75Gln, a CFTR variant involved in the risk of CFTR-related disorders? , 2014, Journal of Human Genetics.

[38]  B. H. Miller,et al.  Central Circadian Control of Female Reproductive Function , 2014, Front. Endocrinol..

[39]  J. Skranes,et al.  Risk of cerebral palsy in term‐born singletons according to growth status at birth , 2014, Developmental medicine and child neurology.

[40]  A. Shah,et al.  Endoplasmic reticulum stress and Nox-mediated reactive oxygen species signaling in the peripheral vasculature: potential role in hypertension. , 2014, Antioxidants & redox signaling.

[41]  M. Chahine,et al.  Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? , 2014, Channels.

[42]  P. Hegyi,et al.  Molecular and Cellular Mechanisms of Disease , 2022 .

[43]  Voltage-Gated Potassium Channels at the Crossroads of Neuronal Function, Ischemic Tolerance, and Neurodegeneration , 2014, Translational Stroke Research.

[44]  D. Julius,et al.  Structure of the TRPV1 ion channel determined by electron cryo-microscopy , 2013, Nature.

[45]  J. Clancy,et al.  Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function. , 2013, American journal of respiratory and critical care medicine.

[46]  M. Weber,et al.  Transient compartment-like syndrome and normokalaemic periodic paralysis due to a Cav1.1 mutation , 2013, Brain : a journal of neurology.

[47]  M. Volpe,et al.  Activation of NADPH Oxidase 4 in the Endoplasmic Reticulum Promotes Cardiomyocyte Autophagy and Survival During Energy Stress Through the Protein Kinase RNA-Activated-Like Endoplasmic Reticulum Kinase/Eukaryotic Initiation Factor 2&agr;/Activating Transcription Factor 4 Pathway , 2013, Circulation research.

[48]  W. Greenhalf,et al.  Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis , 2013, Gut.

[49]  S. Matalon,et al.  Cigarette smoke and CFTR: implications in the pathogenesis of COPD. , 2013, American journal of physiology. Lung cellular and molecular physiology.

[50]  C. Rosen,et al.  IGF-1 regulation of key signaling pathways in bone. , 2013, BoneKEy reports.

[51]  Hong Yu Ren,et al.  VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1 , 2013, Molecular biology of the cell.

[52]  M. Amaral,et al.  Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi , 2013, The FEBS journal.

[53]  C. Livingstone Insulin-like growth factor-I (IGF-I) and clinical nutrition. , 2013, Clinical science.

[54]  D. Cooper,et al.  A Conservative Assessment of the Major Genetic Causes of Idiopathic Chronic Pancreatitis: Data from a Comprehensive Analysis of PRSS1, SPINK1, CTRC and CFTR Genes in 253 Young French Patients , 2013, PloS one.

[55]  S. Collins Oxford Handbook of Obstetrics and Gynaecology , 2013 .

[56]  O. Petersen,et al.  Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy , 2013, Proceedings of the National Academy of Sciences.

[57]  P. Hegyi,et al.  Intraductal acidosis in acute biliary pancreatitis. , 2013, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

[58]  Ayesha Sania,et al.  National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010 , 2013, The Lancet. Global health.

[59]  K. Sunagawa,et al.  The Overexpression of Twinkle Helicase Ameliorates the Progression of Cardiac Fibrosis and Heart Failure in Pressure Overload Model in Mice , 2013, PloS one.

[60]  G. Lukács,et al.  Mechanism-based corrector combination restores ΔF508-CFTR folding and function , 2013, Nature Chemical Biology.

[61]  A. González-Bulnes,et al.  Steroidogenesis in sheep pregnancy with intrauterine growth retardation by high-altitude hypoxia: effects of maternal altitudinal status and antioxidant treatment. , 2013, Reproduction, fertility, and development.

[62]  S. Ledoux,et al.  The maintenance of mitochondrial DNA integrity--critical analysis and update. , 2013, Cold Spring Harbor perspectives in biology.

[63]  Régis Pomès,et al.  Construction and validation of a homology model of the human voltage-gated proton channel hHV1 , 2013, The Journal of general physiology.

[64]  F. Domoki,et al.  Depolarization of Mitochondria in Endothelial Cells Promotes Cerebral Artery Vasodilation by Activation of Nitric Oxide Synthase , 2013, Arteriosclerosis, thrombosis, and vascular biology.

[65]  K. Swartz,et al.  Exploring structure-function relationships between TRP and Kv channels , 2013, Scientific Reports.

[66]  H. Larsson,et al.  Molecular mechanism of voltage sensing in voltage-gated proton channels , 2013, The Journal of general physiology.

[67]  N. Dokholyan,et al.  Regulator (abcc7) Structure Cystic Fibrosis Transmembrane Conductance Perspective the Cystic Fibrosis Gene: a Molecular Genetic Cystic Fibrosis Status of Fluid and Electrolyte Absorption in Phenotypes the Influence of Genetics on Cystic Fibrosis Assessing the Disease-liability of Mutations in Perspe , 2022 .

[68]  Y. Kikkawa,et al.  Mitochondrial DNA Mutations in Mutator Mice Confer Respiration Defects and B-Cell Lymphoma Development , 2013, PloS one.

[69]  M. Falkenberg,et al.  TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication , 2013, Human molecular genetics.

[70]  C. Tahimic,et al.  Anabolic effects of IGF-1 signaling on the skeleton , 2013, Front. Endocrin..

[71]  P. Cohen,et al.  The emerging role of the mitochondrial-derived peptide humanin in stress resistance. , 2013, Journal of molecular endocrinology.

[72]  Letícia Stock,et al.  Structural basis for activation of voltage-gated cation channels. , 2013, Biochemistry.

[73]  H. Larsson,et al.  Subunit Interactions during Cooperative Opening of Voltage-Gated Proton Channels , 2013, Neuron.

[74]  Linda S. Lee,et al.  Cigarette smoking impairs pancreatic duct cell bicarbonate secretion. , 2013, JOP : Journal of the pancreas.

[75]  D. Yellon,et al.  Myocardial ischemia-reperfusion injury: a neglected therapeutic target. , 2013, The Journal of clinical investigation.

[76]  A. Dominiczak,et al.  Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes , 2012, Clinical science.

[77]  A. Fowden,et al.  Endocrine interactions in the control of fetal growth. , 2013, Nestle Nutrition Institute workshop series.

[78]  G. Dorn Mitochondrial dynamics in heart disease. , 2013, Biochimica et biophysica acta.

[79]  Z. Motovska,et al.  Oxidative stress: Predictive marker for coronary artery disease. , 2013, Experimental and clinical cardiology.

[80]  O. Petersen,et al.  The exocrine pancreas: the acinar-ductal tango in physiology and pathophysiology. , 2013, Reviews of physiology, biochemistry and pharmacology.

[81]  S. Cannon,et al.  A calcium channel mutant mouse model of hypokalemic periodic paralysis. , 2012, The Journal of clinical investigation.

[82]  H. Westerblad,et al.  Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice , 2012, The Journal of physiology.

[83]  I. Castilla-Cortázar,et al.  Human conditions of insulin-like growth factor-I (IGF-I) deficiency , 2012, Journal of Translational Medicine.

[84]  M. Klein,et al.  Gating pore currents and the resting state of Nav1.4 voltage sensor domains , 2012, Proceedings of the National Academy of Sciences.

[85]  T. Krieg,et al.  Oxidative and nitrosative stress in the maintenance of myocardial function. , 2012, Free radical biology & medicine.

[86]  D. Meyerholz,et al.  Pancreatic and biliary secretion are both altered in cystic fibrosis pigs. , 2012, American journal of physiology. Gastrointestinal and liver physiology.

[87]  G. Porter,et al.  Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy , 2012, Circulation research.

[88]  Soo-Jung Kim,et al.  Mechanisms of CFTR Folding at the Endoplasmic Reticulum , 2012, Front. Pharmacol..

[89]  B. Wallace,et al.  Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing , 2012, Nature Communications.

[90]  Pratap Kumar,et al.  Hormones in pregnancy , 2012, Nigerian medical journal : journal of the Nigeria Medical Association.

[91]  D. Meyerholz,et al.  Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets. , 2012, The Journal of clinical investigation.

[92]  S. Sifakis,et al.  Endocrine, paracrine, and autocrine placental mediators in labor , 2012, Hormones.

[93]  M. Ko,et al.  Molecular Mechanisms of Pancreatic Stone Formation in Chronic Pancreatitis , 2012, Front. Physio..

[94]  Z. Kassiri,et al.  Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease , 2012, Fibrogenesis & tissue repair.

[95]  M. Fransen,et al.  Role of peroxisomes in ROS/RNS-metabolism: implications for human disease. , 2012, Biochimica et biophysica acta.

[96]  T. Theander,et al.  Factors associated with and causes of perinatal mortality in northeastern Tanzania , 2012, Acta obstetricia et gynecologica Scandinavica.

[97]  P. Durie,et al.  Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in pancreatitis. , 2012, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[98]  J. Castellot,et al.  CCN5 Expression in mammals. III. Early embryonic mouse development , 2012, Journal of Cell Communication and Signaling.

[99]  S. Dudley,et al.  Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation , 2012, Front. Physio..

[100]  A. Marconi,et al.  Placental Amino Acids Transport in Intrauterine Growth Restriction , 2012, Journal of pregnancy.

[101]  R. Khalil,et al.  Molecular Mechanisms Regulating the Vascular Prostacyclin Pathways and Their Adaptation during Pregnancy and in the Newborn , 2012, Pharmacological Reviews.

[102]  M. Dransfield,et al.  A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease , 2012, PloS one.

[103]  J. Hayashi,et al.  Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development , 2012, Proceedings of the National Academy of Sciences.

[104]  F. Lehmann-Horn,et al.  Pathophysiological Role of Omega Pore Current in Channelopathies , 2012, Front. Pharmacol..

[105]  Jianhua He,et al.  Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel , 2012, Nature.

[106]  M. Brink,et al.  A Proton Leak Current through the Cardiac Sodium Channel Is Linked to Mixed Arrhythmia and the Dilated Cardiomyopathy Phenotype , 2012, PloS one.

[107]  L. J. Terlecky,et al.  Peroxisomes, oxidative stress, and inflammation. , 2012, World journal of biological chemistry.

[108]  D. Mparmpakas,et al.  Changes in placental progesterone receptors in term and preterm labour. , 2012, Placenta.

[109]  Shaohui Wang,et al.  WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy. , 2012, Current neurovascular research.

[110]  V. Thu,et al.  NecroX-5 prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter. , 2012, Cardiovascular research.

[111]  P. Rabinovitch,et al.  Mitochondria and cardiovascular aging. , 2012, Circulation research.

[112]  Richard J Martin,et al.  CFTR is the primary known apical glutathione transporter involved in cigarette smoke-induced adaptive responses in the lung. , 2012, Free radical biology & medicine.

[113]  W. Ward,et al.  The Interplay between Estrogen and Fetal Adrenal Cortex , 2012, Journal of nutrition and metabolism.

[114]  F. Bezanilla,et al.  Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain. , 2012, Biophysical journal.

[115]  M. Stumvoll,et al.  CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? , 2012, Gut.

[116]  S. Maulik,et al.  Oxidative stress and cardiac hypertrophy: a review , 2012, Toxicology mechanisms and methods.

[117]  J. Griffin,et al.  The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. , 2012, Free radical biology & medicine.

[118]  D. Clapham,et al.  The Voltage–gated Proton Channel, Hv1, Enhances Brain Damage from Ischemic Stroke , 2012, Nature Neuroscience.

[119]  A S Verkman,et al.  CFTR: folding, misfolding and correcting the ΔF508 conformational defect. , 2012, Trends in molecular medicine.

[120]  J. Riordan,et al.  Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[121]  V. Vilgrain,et al.  Pancreas Divisum Is Not a Cause of Pancreatitis by Itself But Acts as a Partner of Genetic Mutations , 2012, The American Journal of Gastroenterology.

[122]  Klaus Schulten,et al.  Molecular dynamics investigation of the ω-current in the Kv1.2 voltage sensor domains. , 2012, Biophysical journal.

[123]  T. Prolla,et al.  Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice. , 2012, Cell metabolism.

[124]  Yahui Kong,et al.  Oxidative Stress, Mitochondrial Dysfunction, and Aging , 2011, Journal of signal transduction.

[125]  I. Rodríguez-Balderrama,et al.  [Risk factors associated with intrauterine growth restriction in newborns attended in a university hospital]. , 2012, Revista medica del Instituto Mexicano del Seguro Social.

[126]  Min Goo Lee,et al.  Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. , 2012, Physiological reviews.

[127]  E. Isacoff,et al.  The Pore of the Voltage-Gated Proton Channel , 2011, Neuron.

[128]  R. Gottlieb,et al.  Impaired mitophagy at the heart of injury , 2011, Autophagy.

[129]  Matthias Griese,et al.  A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. , 2011, The New England journal of medicine.

[130]  S. Cannon,et al.  A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis. , 2011, The Journal of clinical investigation.

[131]  T. Gheita,et al.  Uterine–umbilical artery Doppler velocimetry and pregnancy outcome in SLE patients: Relation to disease manifestations and activity , 2011 .

[132]  O. Firuzi,et al.  Antioxidant therapy: current status and future prospects. , 2011, Current medicinal chemistry.

[133]  Bryan C Dickinson,et al.  Chemistry and biology of reactive oxygen species in signaling or stress responses. , 2011, Nature chemical biology.

[134]  J. Mehta,et al.  Oxidized Low-Density Lipoprotein and Atherosclerosis Implications in Antioxidant Therapy , 2011, The American journal of the medical sciences.

[135]  G. Lukács,et al.  Protein quality control at the plasma membrane. , 2011, Current opinion in cell biology.

[136]  Olfert Landt,et al.  Common CFTR haplotypes and susceptibility to chronic pancreatitis and congenital bilateral absence of the vas deferens , 2011, Human mutation.

[137]  J. Galpin,et al.  Contributions of Counter-Charge in a Potassium Channel Voltage-Sensor Domain , 2011, Nature chemical biology.

[138]  W. Catterall,et al.  THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL , 2011, Nature.

[139]  Sahil Sharma,et al.  Xanthine oxidase inhibitors: a patent survey , 2011, Expert opinion on therapeutic patents.

[140]  Bernd Nilius,et al.  TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat , 2011, Neuron.

[141]  S. Cannon,et al.  Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia , 2011, Neurology.

[142]  V. Thu,et al.  Cardiac proteomic responses to ischemia–reperfusion injury and ischemic preconditioning , 2011, Expert review of proteomics.

[143]  T. Prolla,et al.  Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and G&agr;q Overexpression–Induced Heart Failure , 2011, Circulation research.

[144]  I. Crocker,et al.  IGF2 Actions on Trophoblast in Human Placenta Are Regulated by the Insulin-Like Growth Factor 2 Receptor, Which Can Function as Both a Signaling and Clearance Receptor1 , 2011, Biology of reproduction.

[145]  Gregory C Kujoth,et al.  Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice , 2011, Proceedings of the National Academy of Sciences.

[146]  D. Spandidos,et al.  Decreased placental expression of hPGH, IGF-I and IGFBP-1 in pregnancies complicated by fetal growth restriction. , 2011, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[147]  Robin A. J. Smith,et al.  Mitochondria-targeted antioxidants as therapies. , 2011, Discovery medicine.

[148]  W. Balch,et al.  Emergent properties of proteostasis in managing cystic fibrosis. , 2011, Cold Spring Harbor perspectives in biology.

[149]  Cesar G Victora,et al.  Cohort Profile: The 2004 Pelotas (Brazil) Birth Cohort Study , 2010, International journal of epidemiology.

[150]  S. Philcox Type of CFTR Mutation Determines Risk of Pancreatitis in Patients With Cystic Fibrosis , 2011 .

[151]  P. Sengupta,et al.  Adenine nucleotide translocase 1 deficiency results in dilated cardiomyopathy with defects in myocardial mechanics, histopathological alterations, and activation of apoptosis. , 2011, JACC. Cardiovascular imaging.

[152]  C. Mammucari,et al.  Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models , 2011, Skeletal Muscle.

[153]  H. Kim,et al.  NecroX as a novel class of mitochondrial reactive oxygen species and ONOO− scavenger , 2010, Archives of pharmacal research.

[154]  F. Vermeulen,et al.  Ataluren (PTC124) induces cystic fibrosis transmembrane conductance regulator protein expression and activity in children with nonsense mutation cystic fibrosis. , 2010, American journal of respiratory and critical care medicine.

[155]  E. Abel,et al.  Mitochondria in the diabetic heart. , 2010, Cardiovascular research.

[156]  P. Veeraveedu,et al.  Role of Differential Signaling Pathways and Oxidative Stress in Diabetic Cardiomyopathy , 2010, Current cardiology reviews.

[157]  M. Westwood,et al.  Maternal growth factor regulation of human placental development and fetal growth. , 2010, The Journal of endocrinology.

[158]  M. Hanna,et al.  Skeletal muscle channelopathies: nondystrophic myotonias and periodic paralysis. , 2010, Current opinion in neurology.

[159]  R. Brandes,et al.  NADPH oxidases in cardiovascular disease. , 2010, Free radical biology & medicine.

[160]  David K Meyerholz,et al.  Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis. , 2010, The Journal of clinical investigation.

[161]  David E. Clapham,et al.  International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family , 2010, Pharmacological Reviews.

[162]  P. Hegyi,et al.  Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells , 2010, Gut.

[163]  S. Yakar,et al.  IGF-1 and Bone: New Discoveries From Mouse Models , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[164]  T. Prolla,et al.  Age‐dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria , 2010, Aging cell.

[165]  R. Kraft,et al.  TRPM3 is expressed in sphingosine‐responsive myelinating oligodendrocytes , 2010, Journal of neurochemistry.

[166]  C. Owyang,et al.  Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue DeltaF508 cystic fibrosis mouse. , 2010, American journal of physiology. Gastrointestinal and liver physiology.

[167]  W. Catterall,et al.  Ion permeation and block of the gating pore in the voltage sensor of NaV1.4 channels with hypokalemic periodic paralysis mutations , 2010, The Journal of general physiology.

[168]  Takuya Miyakawa,et al.  Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice , 2010, PloS one.

[169]  J. Hiltunen,et al.  Peroxisomes are oxidative organelles. , 2010, Antioxidants & redox signaling.

[170]  Robin A. J. Smith,et al.  Animal and human studies with the mitochondria‐targeted antioxidant MitoQ , 2010, Annals of the New York Academy of Sciences.

[171]  A. Trifunovic,et al.  Mitochondrial energy metabolism and ageing. , 2010, Biochimica et biophysica acta.

[172]  M. Hanna,et al.  Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis? , 2010, The Journal of physiology.

[173]  H. Ishiguro,et al.  Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis. , 2010, Gastroenterology.

[174]  B. Pitt,et al.  Serum potassium and outcomes in CKD: insights from the RRI-CKD cohort study. , 2010, Clinical journal of the American Society of Nephrology : CJASN.

[175]  C. Xiaoqing,et al.  Regulation of progesterone receptor A and B expression in human preterm, term, and postterm placental villi , 2010, Acta obstetricia et gynecologica Scandinavica.

[176]  S. Philipp,et al.  TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells , 2010, Pflügers Archiv - European Journal of Physiology.

[177]  D. Rubinsztein,et al.  Mechanisms of cross‐talk between the ubiquitin‐proteasome and autophagy‐lysosome systems , 2010, FEBS letters.

[178]  Xiao Tao,et al.  A Gating Charge Transfer Center in Voltage Sensors , 2010, Science.

[179]  R. Gascoyne,et al.  HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species , 2010, Nature Immunology.

[180]  E. Abel,et al.  Diabetic cardiomyopathy, causes and effects , 2010, Reviews in Endocrine and Metabolic Disorders.

[181]  M. Tarpey,et al.  Hydrogen peroxide is the major oxidant product of xanthine oxidase. , 2010, Free radical biology & medicine.

[182]  A. Wojtovich,et al.  Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria. , 2010, Bioorganic & medicinal chemistry.

[183]  P. Lishko,et al.  Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel , 2010, Cell.

[184]  H. Larsson,et al.  Strong cooperativity between subunits in voltage-gated proton channels , 2009, Nature Structural &Molecular Biology.

[185]  M. Klein,et al.  Double gaps along Shaker S4 demonstrate omega currents at three different closed states , 2010 .

[186]  Eugene D Albrecht,et al.  Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy. , 2010, The International journal of developmental biology.

[187]  C. Kang,et al.  Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive. , 2009, Free radical biology & medicine.

[188]  P. Neufer,et al.  Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. , 2009, Journal of the American College of Cardiology.

[189]  E. Isacoff,et al.  Architecture and gating of Hv1 proton channels , 2009, The Journal of physiology.

[190]  P. Hegyi,et al.  CFTR Expression But Not Cl− Transport Is Involved in the Stimulatory Effect of Bile Acids on Apical Cl−/HCO3− Exchange Activity in Human Pancreatic Duct Cells , 2009, Pancreas.

[191]  P. Rabinovitch,et al.  Cardiac aging in mice and humans: the role of mitochondrial oxidative stress. , 2009, Trends in cardiovascular medicine.

[192]  R. Griggs,et al.  Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias , 2009, Current opinion in neurology.

[193]  João Wosniak,et al.  Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. , 2009, Antioxidants & redox signaling.

[194]  D. Clemmons Role of IGF-I in skeletal muscle mass maintenance , 2009, Trends in Endocrinology & Metabolism.

[195]  A. Annenkov The Insulin-Like Growth Factor (IGF) Receptor Type 1 (IGF1R) as an Essential Component of the Signalling Network Regulating Neurogenesis , 2009, Molecular Neurobiology.

[196]  K. Sjögren,et al.  The role of liver-derived insulin-like growth factor-I. , 2009, Endocrine reviews.

[197]  M. Sridhar,et al.  Changes in GH/IGF-1 Axis in Intrauterine Growth Retardation: Consequences of Fetal Programming? , 2009, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[198]  G. Desoye,et al.  Insulin and the IGF system in the human placenta of normal and diabetic pregnancies , 2009, Journal of anatomy.

[199]  Yongqiang Chen,et al.  Superoxide is the major reactive oxygen species regulating autophagy , 2009, Cell Death and Differentiation.

[200]  Yidong Bai,et al.  Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis , 2009, Cell Research.

[201]  D. Yellon,et al.  Preconditioning and postconditioning: underlying mechanisms and clinical application. , 2009, Atherosclerosis.

[202]  Michael Stumvoll,et al.  Antioxidants prevent health-promoting effects of physical exercise in humans , 2009, Proceedings of the National Academy of Sciences.

[203]  J. R. Figueiredo,et al.  Involvement of growth hormone (GH) and insulin-like growth factor (IGF) system in ovarian folliculogenesis. , 2009, Theriogenology.

[204]  D. Sheppard,et al.  Gating of the CFTR Cl− channel by ATP‐driven nucleotide‐binding domain dimerisation , 2009, The Journal of physiology.

[205]  J. Bomberger,et al.  The Deubiquitinating Enzyme USP10 Regulates the Post-endocytic Sorting of Cystic Fibrosis Transmembrane Conductance Regulator in Airway Epithelial Cells* , 2009, The Journal of Biological Chemistry.

[206]  L. Carbillon Cerebral palsy and restricted growth status at birth: population‐based case‐control study , 2009, BJOG : an international journal of obstetrics and gynaecology.

[207]  Kai Du,et al.  Cooperative assembly and misfolding of CFTR domains in vivo. , 2009, Molecular biology of the cell.

[208]  E. Tuncay,et al.  Antioxidants but not Doxycycline Treatments Restore Depressed Beta-Adrenergic Responses of the Heart in Diabetic Rats , 2009, Cardiovascular Toxicology.

[209]  N. Schmitz,et al.  TWIST-1 is overexpressed in neoplastic choroid plexus epithelial cells and promotes proliferation and invasion. , 2009, Cancer research.

[210]  M. Weber,et al.  K+-dependent paradoxical membrane depolarization and Na+ overload, major and reversible contributors to weakness by ion channel leaks , 2009, Proceedings of the National Academy of Sciences.

[211]  N. Venediktova,et al.  Oxidative stress induces degradation of mitochondrial DNA , 2009, Nucleic acids research.

[212]  W. Fraser,et al.  Absorption, transport, and bioavailability of vitamin e and its role in pregnant women. , 2009, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.

[213]  A. Romo,et al.  Intrauterine growth retardation (IUGR): epidemiology and etiology. , 2009, Pediatric endocrinology reviews : PER.

[214]  S. Umar,et al.  Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart , 2009, Molecular and Cellular Biochemistry.

[215]  W. Catterall,et al.  Depolarization-activated gating pore current conducted by mutant sodium channels in potassium-sensitive normokalemic periodic paralysis , 2008, Proceedings of the National Academy of Sciences.

[216]  V. Flockerzi,et al.  Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells , 2008, Nature Cell Biology.

[217]  K. Lyons,et al.  CTGF inhibits BMP-7 signaling in diabetic nephropathy. , 2008, Journal of the American Society of Nephrology : JASN.

[218]  M. Pollak,et al.  The Type 1 Insulin-Like Growth Factor Receptor Pathway , 2008, Clinical Cancer Research.

[219]  Bernard Perbal,et al.  The CCN family of proteins: structure–function relationships , 2008, Trends in biochemical sciences.

[220]  福家 聡,et al.  DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice , 2008 .

[221]  S. Cannon,et al.  Gating Pore Currents in DIIS4 Mutations of NaV1.4 Associated with Periodic Paralysis: Saturation of Ion Flux and Implications for Disease Pathogenesis , 2008, The Journal of general physiology.

[222]  S. Powers,et al.  Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. , 2008, Physiological reviews.

[223]  David K. Meyerholz,et al.  Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs , 2008, Science.

[224]  Nikolay V. Dokholyan,et al.  Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating* , 2008, Journal of Biological Chemistry.

[225]  Eitan Kerem,et al.  Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial , 2008, The Lancet.

[226]  Patrick Kim Chiaw,et al.  Molecular basis for the ATPase activity of CFTR. , 2008, Archives of biochemistry and biophysics.

[227]  J. Wells,et al.  Cohort profile: the 1993 Pelotas (Brazil) birth cohort study. , 2008, International journal of epidemiology.

[228]  Y. Okamura,et al.  Multimeric nature of voltage-gated proton channels , 2008, Proceedings of the National Academy of Sciences.

[229]  J. Keaney,et al.  Regulation of ROS signal transduction by NADPH oxidase 4 localization , 2008, The Journal of cell biology.

[230]  R. MacKinnon,et al.  Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1 , 2008, Proceedings of the National Academy of Sciences.

[231]  J. Riordan,et al.  CFTR function and prospects for therapy. , 2008, Annual review of biochemistry.

[232]  W. Luo,et al.  Does cardioplegia leave room for postconditioning in paediatric cardiac surgery?* , 2008, Cardiology in the Young.

[233]  C. Velloso Regulation of muscle mass by growth hormone and IGF‐I , 2008, British journal of pharmacology.

[234]  E. Isacoff,et al.  The Voltage-Gated Proton Channel Hv1 Has Two Pores, Each Controlled by One Voltage Sensor , 2008, Neuron.

[235]  J. Muntané,et al.  Mitochondrial protection by low doses of insulin-like growth factor- I in experimental cirrhosis. , 2008, World journal of gastroenterology.

[236]  J. Hayashi,et al.  ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis , 2008, Science.

[237]  M. García-Fernández,et al.  Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats. , 2008, Endocrinology.

[238]  D. Das,et al.  Molecular mechanism of preconditioning , 2008, IUBMB life.

[239]  D. Grammatopoulos,et al.  Placental Corticotrophin‐Releasing Hormone and its Receptors in Human Pregnancy and Labour: Still a Scientific Enigma , 2008, Journal of neuroendocrinology.

[240]  F. Bezanilla How membrane proteins sense voltage , 2008, Nature Reviews Molecular Cell Biology.

[241]  P. Hegyi,et al.  Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig , 2008, Gut.

[242]  S. Peltz,et al.  PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model , 2008, Proceedings of the National Academy of Sciences.

[243]  W. Luo,et al.  Effect of ischemic postconditioning in adult valve replacement. , 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[244]  D. Fowler,et al.  Partial Restoration of Mutant Enzyme Homeostasis in Three Distinct Lysosomal Storage Disease Cell Lines by Altering Calcium Homeostasis , 2008, PLoS biology.

[245]  A. Donner,et al.  Methodological considerations in implementing the WHO Global Survey for Monitoring Maternal and Perinatal Health. , 2008, Bulletin of the World Health Organization.

[246]  J. Viña,et al.  Moderate exercise is an antioxidant: upregulation of antioxidant genes by training. , 2008, Free radical biology & medicine.

[247]  H. Szeto Cell-permeable, mitochondrial-targeted, peptide antioxidants , 2006, The AAPS Journal.

[248]  P. Toogood Mitochondrial drugs. , 2008, Current opinion in chemical biology.

[249]  J. Gómez Growth hormone and insulin-like growth factor-I as an endocrine axis in Alzheimer's disease. , 2008, Endocrine, metabolic & immune disorders drug targets.

[250]  A naturally occurring omega current in a Kv3 family potassium channel from a platyhelminth , 2008, BMC Neuroscience.

[251]  S. Isaranurug,et al.  A population-based cohort study of effect of maternal risk factors on low birthweight in Thailand. , 2007, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

[252]  E. Campbell,et al.  Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment , 2007, Nature.

[253]  Benoît Roux,et al.  Closing In on the Resting State of the Shaker K+ Channel , 2007, Neuron.

[254]  Francis G Spinale,et al.  Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. , 2007, Physiological reviews.

[255]  Ajay M Shah,et al.  Oxidative stress and redox signalling in cardiac hypertrophy and heart failure , 2006, Heart.

[256]  A. Halestrap,et al.  The role of mitochondria in protection of the heart by preconditioning , 2007, Biochimica et biophysica acta.

[257]  J S Armstrong,et al.  Mitochondrial Medicine: Pharmacological targeting of mitochondria in disease , 2007, British journal of pharmacology.

[258]  J. Forman-Kay,et al.  CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices , 2007, Nature Structural &Molecular Biology.

[259]  W. Luo,et al.  Postconditioning in cardiac surgery for tetralogy of Fallot. , 2007, The Journal of thoracic and cardiovascular surgery.

[260]  Brian D. Barnes,et al.  Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction. , 2007, Journal of applied physiology.

[261]  T. Hermann,et al.  Aminoglycoside antibiotics: old drugs and new therapeutic approaches , 2007, Cellular and Molecular Life Sciences.

[262]  Z. Elazar,et al.  Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 , 2007, The EMBO journal.

[263]  J. Rousset,et al.  In vitro prediction of stop-codon suppression by intravenous gentamicin patients with cystic fibrosis : a pilot study , 2022 .

[264]  W. Catterall,et al.  Gating pore current in an inherited ion channelopathy , 2007, Nature.

[265]  J. Prieto,et al.  [Insulin-like growth factor I (IGF-I) and liver cirrhosis]. , 2007, Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.

[266]  B. Kerem,et al.  Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin. , 2007, The Journal of clinical investigation.

[267]  D. Kelly,et al.  Insulin-Resistant Heart Exhibits a Mitochondrial Biogenic Response Driven by the Peroxisome Proliferator-Activated Receptor-&agr;/PGC-1&agr; Gene Regulatory Pathway , 2007, Circulation.

[268]  H. Szeto,et al.  A Novel Cell-permeable Antioxidant Peptide, SS31, Attenuates Ischemic Brain Injury by Down-regulating CD36* , 2007, Journal of Biological Chemistry.

[269]  E. Isacoff,et al.  The twisted ion-permeation pathway of a resting voltage-sensing domain , 2007, Nature.

[270]  T. Prolla,et al.  The Role of Mitochondrial DNA Mutations in Mammalian Aging , 2007, PLoS genetics.

[271]  D. Kass,et al.  Role of oxidative stress in cardiac hypertrophy and remodeling. , 2007, Hypertension.

[272]  Robin A. J. Smith,et al.  Targeting antioxidants to mitochondria by conjugation to lipophilic cations. , 2007, Annual review of pharmacology and toxicology.

[273]  C. Kanaka-Gantenbein,et al.  Causes of Intrauterine Growth Restriction and the Postnatal Development of the Metabolic Syndrome , 2006, Annals of the New York Academy of Sciences.

[274]  M. Röcken,et al.  ‘To repair or not to repair – no longer a question’: repair of mitochondrial DNA shielding against age and cancer , 2006, Experimental dermatology.

[275]  S. Batra,et al.  Cigarette Smoke-induced Differential Expression of the Genes Involved in Exocrine Function of the Rat Pancreas , 2006, Pancreas.

[276]  Angus C Nairn,et al.  In vivo phosphorylation of CFTR promotes formation of a nucleotide‐binding domain heterodimer , 2006, The EMBO journal.

[277]  Teresa Chen,et al.  Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. , 2006, Journal of the American College of Cardiology.

[278]  S. Bernasconi,et al.  Changes in interleukin-6 and IGF system and their relationships in placenta and cord blood in newborns with fetal growth restriction compared with controls. , 2006, European journal of endocrinology.

[279]  Mario J. Garcia,et al.  Effects of selective matrix metalloproteinase inhibitor (PG-116800) to prevent ventricular remodeling after myocardial infarction: results of the PREMIER (Prevention of Myocardial Infarction Early Remodeling) trial. , 2006, Journal of the American College of Cardiology.

[280]  Jeffrey S. Robinson,et al.  Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth. , 2006, Endocrinology.

[281]  D. Maulik Management of Fetal Growth Restriction: An Evidence-Based Approach , 2006, Clinical obstetrics and gynecology.

[282]  M. Merialdi,et al.  Reduction in Neonatal Mortality in Chile Between 1990 and 2000 , 2006, Pediatrics.

[283]  Yasushi Okamura,et al.  A Voltage Sensor-Domain Protein Is a Voltage-Gated Proton Channel , 2006, Science.

[284]  David E. Clapham,et al.  A voltage-gated proton-selective channel lacking the pore domain , 2006, Nature.

[285]  S. Moncada,et al.  Mitochondria as signaling organelles in the vascular endothelium. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[286]  Roger Smith,et al.  Endocrine regulation of human fetal growth: the role of the mother, placenta, and fetus. , 2006, Endocrine reviews.

[287]  M. Freemark Regulation of Maternal Metabolism by Pituitary and Placental Hormones: Roles in Fetal Development and Metabolic Programming , 2006, Hormone Research in Paediatrics.

[288]  J. Lawler,et al.  Exercise training attenuates age‐induced elevation in Bax/Bcl‐2 ratio, apoptosis, and remodeling in the rat heart , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[289]  W. Zimmermann,et al.  Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature. , 2006, Reproduction.

[290]  F. Tronche,et al.  Hepatocyte proliferation during liver regeneration is impaired in mice with liver‐specific IGF‐1R knockout , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[291]  C. Victora,et al.  Cohort profile: the 1982 Pelotas (Brazil) birth cohort study. , 2006, International journal of epidemiology.

[292]  Paola Vergani,et al.  The ABC protein turned chloride channel whose failure causes cystic fibrosis , 2006, Nature.

[293]  J. Neoptolemos,et al.  Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis. , 2006, Gastroenterology.

[294]  Laura C. Greaves,et al.  Mitochondrial DNA mutations in human disease , 2006, IUBMB life.

[295]  M. W. Anders,et al.  Targeting antioxidants to mitochondria: a new therapeutic direction. , 2006, Biochimica et biophysica acta.

[296]  C. Sevier,et al.  Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[297]  R. Wilkins,et al.  Electrophysiological Demonstration of Voltage- Activated H+ Channels in Bovine Articular Chondrocytes , 2006, Cellular Physiology and Biochemistry.

[298]  K. Turksen,et al.  Isolation and characterization , 2006 .

[299]  K. Chayama,et al.  Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. , 2006, Recent patents on cardiovascular drug discovery.

[300]  H. Brinkmeier,et al.  Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains , 2006, BMC Genomics.

[301]  H. Jacobs,et al.  Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[302]  K. Clarke,et al.  Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels. , 2005, Diabetes.

[303]  E. Abel,et al.  Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity , 2005, Circulation.

[304]  W. Greenhalf,et al.  Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers , 2005, Human mutation.

[305]  M. Corey,et al.  The cystic fibrosis transmembrane conductance regulator gene and ion channel function in patients with idiopathic pancreatitis , 2005, Human Genetics.

[306]  Pinchas Cohen,et al.  The role of the insulin-like growth factor system in prenatal growth. , 2005, Molecular genetics and metabolism.

[307]  Kai Du,et al.  Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. , 2005, The Journal of clinical investigation.

[308]  E. Campbell,et al.  Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K+ Channel , 2005, Science.

[309]  Y. Hao,et al.  A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice. , 2005, Gastroenterology.

[310]  J. Sastre,et al.  Decreasing xanthine oxidase‐mediated oxidative stress prevents useful cellular adaptations to exercise in rats , 2005, The Journal of physiology.

[311]  L. Wold,et al.  Oxidative stress and stress signaling: menace of diabetic cardiomyopathy , 2005, Acta Pharmacologica Sinica.

[312]  W. Catterall,et al.  Ion Permeation through a Voltage- Sensitive Gating Pore in Brain Sodium Channels Having Voltage Sensor Mutations , 2005, Neuron.

[313]  T. D. Pugh,et al.  Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging , 2005, Science.

[314]  M. Weinstock The potential influence of maternal stress hormones on development and mental health of the offspring , 2005, Brain, Behavior, and Immunity.

[315]  Robin A. J. Smith,et al.  Synthesis and Characterization of a Triphenylphosphonium-conjugated Peroxidase Mimetic , 2005, Journal of Biological Chemistry.

[316]  Veit Flockerzi,et al.  Alternative Splicing Switches the Divalent Cation Selectivity of TRPM3 Channels* , 2005, Journal of Biological Chemistry.

[317]  J. Weinberg,et al.  Prenatal Alcohol Exposure and Fetal Programming: Effects on Neuroendocrine and Immune Function , 2005, Experimental biology and medicine.

[318]  Guido Davidzon,et al.  Mitochondrial DNA and disease , 2005, Annals of medicine.

[319]  E. Kerem,et al.  Pancreatitis Among Patients With Cystic Fibrosis: Correlation With Pancreatic Status and Genotype , 2005, Pediatrics.

[320]  S. Yusuf,et al.  Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. , 2005, JAMA.

[321]  E. Isacoff,et al.  Voltage-Sensing Arginines in a Potassium Channel Permeate and Occlude Cation-Selective Pores , 2005, Neuron.

[322]  S. Kajimura,et al.  Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[323]  B. Lowell,et al.  Mitochondrial Dysfunction and Type 2 Diabetes , 2005, Science.

[324]  M. Runge,et al.  Oxidative Stress and Vascular Disease , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[325]  R. Guyton,et al.  Remote postconditioning. Brief renal ischemia and reperfusion applied before coronary artery reperfusion reduces myocardial infarct size via endogenous activation of adenosine receptors. , 2005, Basic research in cardiology.

[326]  J. Riordan,et al.  Assembly of functional CFTR chloride channels. , 2005, Annual review of physiology.

[327]  P. Laforêt,et al.  New mutations of SCN4A cause a potassium-sensitive normokalemic periodic paralysis , 2004, Neurology.

[328]  Robert W. Taylor,et al.  The epidemiology of mitochondrial disorders--past, present and future. , 2004, Biochimica et biophysica acta.

[329]  R. Malik,et al.  Diabetic cardiomyopathy: mechanisms, diagnosis and treatment. , 2004, Clinical science.

[330]  R. Gottlieb Autophagy in Health and Disease , 2004, Science.

[331]  C. Wild,et al.  Maternal nutritional risk factors for small for gestational age babies in a developed country: a case-control study , 2004, Archives of Disease in Childhood - Fetal and Neonatal Edition.

[332]  J. Neoptolemos,et al.  Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[333]  N. Khaper,et al.  Inflammatory cytokines and postmyocardial infarction remodeling. , 2004, Circulation research.

[334]  Howard T. Jacobs,et al.  Premature ageing in mice expressing defective mitochondrial DNA polymerase , 2004, Nature.

[335]  C. Dence,et al.  Effect of Obesity and Insulin Resistance on Myocardial Substrate Metabolism and Efficiency in Young Women , 2004, Circulation.

[336]  M. Hori,et al.  Activation of Matrix Metalloproteinases Precedes Left Ventricular Remodeling in Hypertensive Heart Failure Rats: Its Inhibition as a Primary Effect of Angiotensin-Converting Enzyme Inhibitor , 2004, Circulation.

[337]  N. Metreveli,et al.  Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. , 2004, Diabetes.

[338]  C. Wainwright Matrix metalloproteinases, oxidative stress and the acute response to acute myocardial ischaemia and reperfusion. , 2004, Current opinion in pharmacology.

[339]  S. Khouri,et al.  A practical approach to the echocardiographic evaluation of diastolic function. , 2004, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[340]  P. Delafontaine,et al.  Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[341]  R. Mecham,et al.  Oxidative Cross-linking of Tryptophan to Glycine Restrains Matrix Metalloproteinase Activity , 2004, Journal of Biological Chemistry.

[342]  R. Wu,et al.  Oxidative Stress in Hypertension , 2004, Clinical and experimental hypertension.

[343]  D. Mele,et al.  Oxidative stress during myocardial ischaemia and heart failure. , 1998, Current pharmaceutical design.

[344]  P. Reddanna,et al.  Dietary supplementation of Vitamin E protects heart tissue from exercise-induced oxidant stress , 1992, Molecular and Cellular Biochemistry.

[345]  R. Weisel,et al.  Effect of orally administered alpha-tocopheryl acetate on human myocardial alpha-tocopherol levels , 1991, Cardiovascular Drugs and Therapy.

[346]  K. R. Maples,et al.  Nitrone-Related Therapeutics , 2004, CNS drugs.

[347]  Xavier Estivill,et al.  Variation in a repeat sequence determines whether a common variant of the cystic fibrosis transmembrane conductance regulator gene is pathogenic or benign. , 2004, American journal of human genetics.

[348]  M. Yacoub,et al.  Antioxidants in myocardial ischemia-reperfusion injury: therapeutic potential and basic mechanisms. , 2003, Archives of biochemistry and biophysics.

[349]  M. Mocanu,et al.  p53 down‐regulation: a new molecular mechanism involved in ischaemic preconditioning , 2003, FEBS letters.

[350]  M. Duchen,et al.  Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury. , 2003, Cardiovascular research.

[351]  A. Shah,et al.  Oxidative stress in heart failure. More than just damage. , 2003, European heart journal.

[352]  Pinchas Cohen,et al.  Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[353]  Robin A. J. Smith,et al.  Mitochondria‐targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[354]  V. López-Olmos,et al.  Insulin-like growth factor I (IGF-I) regulates endocrine activity of the embryonic testis in the mouse , 2003, The Journal of Steroid Biochemistry and Molecular Biology.

[355]  A. Juul Serum levels of insulin-like growth factor I and its binding proteins in health and disease. , 2003, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[356]  R. Guyton,et al.  Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. , 2003, American journal of physiology. Heart and circulatory physiology.

[357]  Kieran Clarke,et al.  Abnormal Cardiac and Skeletal Muscle Energy Metabolism in Patients With Type 2 Diabetes , 2003, Circulation.

[358]  G. Schultz,et al.  Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3* , 2003, Journal of Biological Chemistry.

[359]  T. DeCoursey,et al.  Properties of Single Voltage-gated Proton Channels in Human Eosinophils Estimated by Noise Analysis and by Direct Measurement , 2003, The Journal of general physiology.

[360]  John Calvin Reed,et al.  Humanin peptide suppresses apoptosis by interfering with Bax activation , 2003, Nature.

[361]  Douglas L. Rothman,et al.  Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance , 2003, Science.

[362]  Steven M Holland,et al.  Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. , 2003, The Journal of clinical investigation.

[363]  Jun Ren,et al.  Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. , 2003, Diabetes.

[364]  B. Nilius,et al.  Homo‐ and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6 , 2003, The EMBO journal.

[365]  Edward G Lakatta,et al.  Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part III: Cellular and Molecular Clues to Heart and Arterial Aging , 2003, Circulation.

[366]  Jiandie D. Lin,et al.  Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. , 2003, The Journal of biological chemistry.

[367]  Steven P Jones,et al.  Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion. , 2003, American journal of physiology. Heart and circulatory physiology.

[368]  R. O'Connor,et al.  Insulin‐like growth factor‐1 activates Akt and Jun N‐terminal kinases (JNKs) in promoting the survival of T lymphocytes , 2002, Immunology.

[369]  M. Corey,et al.  Genotype and phenotype correlations in patients with cystic fibrosis and pancreatitis. , 2002, Gastroenterology.

[370]  R. Baxter,et al.  Cellular actions of the insulin-like growth factor binding proteins. , 2002, Endocrine reviews.

[371]  J. Brosens,et al.  The myometrial junctional zone spiral arteries in normal and abnormal pregnancies: a review of the literature. , 2002, American journal of obstetrics and gynecology.

[372]  L. Giudice,et al.  Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane. , 2002, The Journal of clinical endocrinology and metabolism.

[373]  F. Bezanilla,et al.  Tracking Voltage-dependent Conformational Changes in Skeletal Muscle Sodium Channel during Activation , 2002, The Journal of general physiology.

[374]  Francisco Bezanilla,et al.  Voltage Sensor Movements , 2002, The Journal of general physiology.

[375]  R. Horn Coupled Movements in Voltage-gated Ion Channels , 2002, The Journal of general physiology.

[376]  E. Isacoff,et al.  Molecular Models of Voltage Sensing , 2002, The Journal of general physiology.

[377]  Yau-Huei Wei,et al.  Oxidative Stress , Mitochondrial DNA Mutation , and Impairment of Antioxidant Enzymes in Aging 1 , 2002 .

[378]  Eva L Feldman,et al.  Control of cell survival by IGF signaling pathways. , 2002, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[379]  P. Chinnery,et al.  Normokalemic periodic paralysis revisited: Does it exist? , 2002, Annals of neurology.

[380]  C. C. Pillai,et al.  Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice. , 2002, The Journal of clinical investigation.

[381]  J. Guibourdenche,et al.  Human placental growth hormone--a review. , 2002, Placenta.

[382]  J. Widdicombe,et al.  Acid secretion and proton conductance in human airway epithelium. , 2002, American journal of physiology. Cell physiology.

[383]  A. Szewczyk,et al.  Mitochondria as a Pharmacological Target , 2002, Pharmacological Reviews.

[384]  C. Patterson,et al.  Postischemic Recovery of Contractile Function is Impaired in SOD2+/− but Not SOD1+/− Mouse Hearts , 2002, Circulation.

[385]  J. Stuart,et al.  Superoxide activates mitochondrial uncoupling proteins , 2002, Nature.

[386]  T. Gómez-Isla,et al.  Serum insulin-like growth factor I regulates brain amyloid-beta levels. , 2002, Nature medicine.

[387]  Sang-Oh Yoon,et al.  Sustained production of H(2)O(2) activates pro-matrix metalloproteinase-2 through receptor tyrosine kinases/phosphatidylinositol 3-kinase/NF-kappa B pathway. , 2002, The Journal of biological chemistry.

[388]  D. Dunger,et al.  The Somatotropic Axis in Short Children Born Small for Gestational Age: Relation to Insulin Resistance , 2002, Pediatric Research.

[389]  M. Knowles,et al.  Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. , 2001, Gastroenterology.

[390]  J. Prieto,et al.  Insulin-like growth factor-I restores the reduced somatostatinergic tone controlling growth hormone secretion in cirrhotic rats. , 2001, Liver.

[391]  V. Han,et al.  Control of growth and development of the feto-placental unit. , 2001, Current opinion in pharmacology.

[392]  W. Parks,et al.  Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7) , 2001, The Journal of Biological Chemistry.

[393]  OlivierMeilhac,et al.  Role of Arterial Wall Antioxidant Defense in Beneficial Effects of Exercise on Atherosclerosis in Mice , 2001 .

[394]  Z. Laron,et al.  Insulin-like growth factor 1 (IGF-1): a growth hormone , 2001, Molecular pathology : MP.

[395]  H. Blum,et al.  Mutations of the cystic fibrosis gene in patients with chronic pancreatitis , 2001, American Journal of Gastroenterology.

[396]  P. Chidiac,et al.  Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK. , 2001, The Journal of clinical endocrinology and metabolism.

[397]  P. Czernichow,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Impaired Regulation of Glucose Transporter 4 Gene Expression in Insulin Resistance Associated with in , 2000 .

[398]  J. Pell,et al.  Pregnancy complications and maternal risk of ischaemic heart disease: a retrospective cohort study of 129 290 births , 2001, The Lancet.

[399]  S. Gabbe,et al.  Intrauterine growth restriction , 2001 .

[400]  J. Clancy,et al.  Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis. , 2001, American journal of respiratory and critical care medicine.

[401]  J. Prieto,et al.  Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats. , 2001, Biochimica et biophysica acta.

[402]  G. Sobue,et al.  A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[403]  Francisco Bezanilla,et al.  Histidine Scanning Mutagenesis of Basic Residues of the S4 Segment of the Shaker K+ Channel , 2001, The Journal of general physiology.

[404]  M. Pickard,et al.  Thyroid hormone receptor expression in rat placenta. , 2001, Placenta.

[405]  H. Randeva,et al.  The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy. , 2001, Molecular genetics and metabolism.

[406]  J. Terwilliger,et al.  Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. , 2001, Developmental biology.

[407]  J. Manning,et al.  Prenatal programming of adult hypertension in the rat. , 2001, Kidney international.

[408]  C. Wollheim,et al.  Mitochondrial function in normal and diabetic beta-cells. , 2001, Nature.

[409]  W. Colucci,et al.  Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. , 2001, American journal of physiology. Cell physiology.

[410]  M. Westwood,et al.  Regulation of IGF bioavailability in pregnancy. , 2001, Molecular human reproduction.

[411]  R. Wiklund,et al.  Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients , 2000 .

[412]  J. Mott,et al.  Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis. , 2000, Genomics.

[413]  Christopher Miller An overview of the potassium channel family , 2000, Genome Biology.

[414]  T. Rohan,et al.  Role of the insulin-like growth factor family in cancer development and progression. , 2000, Journal of the National Cancer Institute.

[415]  K. Davies,et al.  Mitochondrial free radical generation, oxidative stress, and aging. , 2000, Free radical biology & medicine.

[416]  M. Manns,et al.  Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis , 2000, American Journal of Gastroenterology.

[417]  T. Bocan,et al.  MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. , 2000, Cardiovascular research.

[418]  S. Handwerger,et al.  The Roles of Placental Growth Hormone and Placental Lactogen in the Regulation of Human Fetal Growth and Development , 2000, Journal of pediatric endocrinology & metabolism : JPEM.

[419]  H. Li,et al.  Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[420]  D. Sorescu,et al.  NAD(P)H oxidase: role in cardiovascular biology and disease. , 2000, Circulation research.

[421]  N. Groome,et al.  Production of inhibin forms by the fetal membranes, decidua, placenta and fetus at parturition. , 2000, Human reproduction.

[422]  C. Duan,et al.  Phosphatidylinositol 3-kinase is required for insulin-like growth factor-I-induced vascular smooth muscle cell proliferation and migration. , 2000, Circulation research.

[423]  V. Hwa,et al.  The Insulin-like Growth Factor-binding Protein (igfbp) Superfamily* , 2022 .

[424]  A. Brusco,et al.  Polyvariant mutant CFTR genes in patients with chronic pancreatitis , 1999, Clinical genetics.

[425]  V. Mootha,et al.  Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1 , 1999, Cell.

[426]  A. Hattersley,et al.  The fetal insulin hypothesis: an alternative explanation of the association of low bir thweight with diabetes and vascular disease , 1999, The Lancet.

[427]  A. Rao,et al.  Progesterone receptor expression in the human placenta. , 1999, Molecular human reproduction.

[428]  S. Melov,et al.  Mitochondrial disease in mouse results in increased oxidative stress. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[429]  J R Yates,et al.  The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[430]  W. Chan,et al.  Effect of pregnancy-specific beta 1-glycoprotein on the development of preimplantation embryo. , 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[431]  E. Wilson,et al.  Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily. , 1999, The Journal of clinical endocrinology and metabolism.

[432]  Jens C. Brüning,et al.  Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression , 1999, Nature Genetics.

[433]  D. Luk,et al.  Human HtrA, an Evolutionarily Conserved Serine Protease Identified as a Differentially Expressed Gene Product in Osteoarthritic Cartilage* , 1998, The Journal of Biological Chemistry.

[434]  A. Bochenek,et al.  Evaluation of perioperative myocardial tissue damage in ischemically preconditioned human heart during aorto coronary bypass surgery. , 1998, The Journal of cardiovascular surgery.

[435]  Richard E. White,et al.  Hydrogen peroxide relaxes porcine coronary arteries by stimulating BKCachannel activity. , 1998, American journal of physiology. Heart and circulatory physiology.

[436]  W. Rossmanith,et al.  Detection of gonadotrophin releasing hormone and its receptor mRNA in human placental trophoblasts using in-situ reverse transcription-polymerase chain reaction. , 1998, Molecular human reproduction.

[437]  M. Knowles,et al.  Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. , 1998, The New England journal of medicine.

[438]  L. Packer,et al.  Networking antioxidants in the isolated rat heart are selectively depleted by ischemia-reperfusion. , 1998, Free radical biology & medicine.

[439]  M. Goossens,et al.  Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation. , 1998, The Journal of clinical investigation.

[440]  M. Blössner,et al.  Levels and patterns of intrauterine growth retardation in developing countries. , 1998, European journal of clinical nutrition.

[441]  J. Prieto,et al.  Osteopenia in rats with liver cirrhosis: beneficial effects of IGF-I treatment. , 1998, Journal of hepatology.

[442]  K. Hornbrook,et al.  Lipid peroxidation, antioxidant protection and aging. , 1997, Biochimica et biophysica acta.

[443]  S. Mohan,et al.  Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. , 1997, Endocrine reviews.

[444]  R. Goldenberg,et al.  Small for gestational age and intrauterine growth restriction: definitions and standards. , 1997, Clinical obstetrics and gynecology.

[445]  Francisco Bezanilla,et al.  Voltage-Dependent Proton Transport by the Voltage Sensor of the Shaker K+ Channel , 1997, Neuron.

[446]  T. Wagner,et al.  A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[447]  T. Siler-Khodr,et al.  Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation. , 1997, The Journal of maternal-fetal medicine.

[448]  W. Luo,et al.  Preconditioning improves myocardial preservation in patients undergoing open heart operations. , 1997, The Annals of thoracic surgery.

[449]  J. Clancy,et al.  Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line , 1997, Nature Medicine.

[450]  F. Bezanilla,et al.  Characterizing Voltage-Dependent Conformational Changes in the Shaker K+ Channel with Fluorescence , 1997, Neuron.

[451]  J. Prieto,et al.  Hepatoprotective effects of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis. , 1997, Gastroenterology.

[452]  D. Wallace,et al.  Mitochondrial DNA in aging and disease. , 1997, Scientific American.

[453]  G. Desoye,et al.  Location of insulin receptors in the placenta and its progenitor tissues , 1997, Microscopy research and technique.

[454]  F. de Zegher,et al.  Clinical review 89: Small as fetus and short as child: from endogenous to exogenous growth hormone. , 1997, The Journal of clinical endocrinology and metabolism.

[455]  D. Wallace,et al.  A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator , 1997, Nature Genetics.

[456]  M. Muyan,et al.  Secretion of chorionic gonadotropin from human trophoblasts. , 1997, Placenta.

[457]  D. Clemmons Insulin-like growth factor binding proteins and their role in controlling IGF actions. , 1997, Cytokine & growth factor reviews.

[458]  K. Alitalo,et al.  Expression of vascular endothelial growth factor and placenta growth factor in human placenta. , 1997, Biology of reproduction.

[459]  C. H. Smith,et al.  Spatial Polarization of Insulin-Like Growth Factor Receptors on the Human Syncytiotrophoblast , 1997, Pediatric Research.

[460]  D. Le Roith Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors. , 1997, The New England journal of medicine.

[461]  F. Petraglia Inhibin, activin and follistatin in the human placenta--a new family of regulatory proteins. , 1997, Placenta.

[462]  B. Kerem,et al.  Cystic fibrosis in Jews: frequency and mutation distribution. , 1997, Genetic testing.

[463]  J. Jansson,et al.  Insulin-like growth factors stimulate expression of hepatocyte growth factor but not transforming growth factor beta1 in cultured hepatic stellate cells. , 1997, Endocrinology.

[464]  H. Hoffman,et al.  Prediction of fetal growth based on maternal serum concentrations of human chorionic gonadotropin, human placental lactogen and estriol. , 1997, Acta obstetricia et gynecologica Scandinavica. Supplement.

[465]  S. Nagalla,et al.  Synthesis and Characterization of Insulin-like Growth Factor-binding Protein (IGFBP)-7 , 1996, The Journal of Biological Chemistry.

[466]  M. Savage,et al.  Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. , 1996, The New England journal of medicine.

[467]  J R Florini,et al.  Growth hormone and the insulin-like growth factor system in myogenesis. , 1996, Endocrine reviews.

[468]  J. Tavernier,et al.  ESM-1 Is a Novel Human Endothelial Cell-specific Molecule Expressed in Lung and Regulated by Cytokines* , 1996, The Journal of Biological Chemistry.

[469]  J. Baker,et al.  Effects of an Igf1 gene null mutation on mouse reproduction. , 1996, Molecular endocrinology.

[470]  D. Bedwell,et al.  Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations , 1996, Nature Medicine.

[471]  T. Chard,et al.  Circulating levels of IGF-I and IGF-binding protein-1 throughout pregnancy: relation to birthweight and maternal weight. , 1996, The Journal of endocrinology.

[472]  E. Isacoff,et al.  Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating , 1996, Science.

[473]  J. Ruppersberg Ion Channels in Excitable Membranes , 1996 .

[474]  R. Hirschberg Insulin-like growth factor I in the kidney. , 1996, Mineral and electrolyte metabolism.

[475]  R. Horn,et al.  Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels , 1996, Neuron.

[476]  E. Barrett,et al.  Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms. , 1995, The Journal of clinical investigation.

[477]  R. Horn,et al.  Evidence for voltage-dependent S4 movement in sodium channels , 1995, Neuron.

[478]  Yu Huang,et al.  Electrostatic interactions of S4 voltage sensor in shaker K+ channel , 1995, Neuron.

[479]  H. Matsuo,et al.  Insulin-like growth factor-I as a local regulator of proliferation and differentiated function of the human trophoblast in early pregnancy. , 1995, Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy.

[480]  L. Giudice,et al.  Growth factors in reproduction , 1995, Trends in Endocrinology & Metabolism.

[481]  M. Miyata,et al.  Cardiac involvement in mitochondrial diseases. A study on 17 patients with documented mitochondrial DNA defects. , 1995, Circulation.

[482]  D. Clemmons,et al.  Insulin-like growth factors and their binding proteins: biological actions. , 1995, Endocrine reviews.

[483]  F. Xiaodong,et al.  The protective effects of high-dose ascorbic acid on myocardium against reperfusion injury during and after cardiopulmonary bypass. , 1994, The Thoracic and cardiovascular surgeon.

[484]  T. Chard Insulin-like growth factors and their binding proteins in normal and abnormal human fetal growth. , 1994, Growth regulation.

[485]  E. Reece,et al.  The Relation Between Human Fetal Growth and Fetal Blood Levels of Insulin‐Like Growth Factors I and II, Their Binding Proteins, and Receptors , 1994, Obstetrics and gynecology.

[486]  D. Porteous,et al.  CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. , 1994, The American journal of physiology.

[487]  L. Powell-Braxton,et al.  IGF-I is required for normal embryonic growth in mice. , 1993, Genes & development.

[488]  J. Baker,et al.  Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) , 1993, Cell.

[489]  C. Conover,et al.  Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1 , 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[490]  M. Murphy,et al.  Identification and characterization of genes differentially expressed in meningiomas. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[491]  R. Kloner,et al.  Regional Ischemic 'Preconditioning' Protects Remote Virgin Myocardium From Subsequent Sustained Coronary Occlusion , 1993, Circulation.

[492]  Ronald G. Crystal,et al.  Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA , 1993, Nature Genetics.

[493]  D. Clemmons,et al.  The insulin-like growth factors. , 1993, Annual review of physiology.

[494]  M. Carson,et al.  Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. , 1993, Neuron.

[495]  J. Hadden,et al.  Thymic Involution in Aging Prospects for Correction , 1992, Annals of the New York Academy of Sciences.

[496]  R. Deter,et al.  Detection of intrauterine growth retardation in twins using individualized growth assessment. II. Evaluation of third‐trimester growth and prediction of growth outcome at birth , 1992, Journal of clinical ultrasound : JCU.

[497]  L. Giudice Insulin-like growth factors and ovarian follicular development. , 1992, Endocrine reviews.

[498]  Junyan Zhang,et al.  Maternal levels of prostacyclin, thromboxane, vitamin E and lipid peroxides throughout normal pregnancy , 1992 .

[499]  J. Starnes,et al.  Exercise training improves cardiac function after ischemia in the isolated, working rat heart. , 1992, The American journal of physiology.

[500]  K. Dorshkind,et al.  Insulin-like growth factor-I regulates pro-B cell differentiation. , 1992, Blood.

[501]  Richard C. Boucher,et al.  Defective Epithelial Chloride Transport in a Gene-Targeted Mouse Model of Cystic Fibrosis , 1992, Science.

[502]  B. Koller,et al.  An Animal Model for Cystic Fibrosis Made by Gene Targeting , 1992, Science.

[503]  C. Librach,et al.  Localization and regulation of the activin-A dimer in human placental cells. , 1992, The Journal of clinical endocrinology and metabolism.

[504]  M. Corey,et al.  Genetic determination of exocrine pancreatic function in cystic fibrosis. , 1992, American journal of human genetics.

[505]  T Chard,et al.  Customised antenatal growth charts , 1992, The Lancet.

[506]  V. Becker,et al.  Doppler flow measurements and histomorphology of the placental bed in uteroplacental insufficiency , 1992, Journal of perinatal medicine.

[507]  S. E. Knowles,et al.  IGF-I and its variant, des-(1-3)IGF-I, enhance growth in rats with reduced renal mass. , 1991, The American journal of physiology.

[508]  O. Alfieri,et al.  Oxygen free radicals and myocardial damage: protective role of thiol-containing agents. , 1991, The American journal of medicine.

[509]  Gary R. Grotendorst,et al.  Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10 , 1991, The Journal of cell biology.

[510]  A. Caufriez,et al.  Insulin-like growth factor I: a good indicator of functional hepatocellular capacity in alcoholic liver cirrhosis , 1991, Journal of endocrinological investigation.

[511]  D. Clemmons,et al.  Nutritional regulation of IGF-I and IGF binding proteins. , 1991, Annual review of nutrition.

[512]  M. Binoux,et al.  Cerebrospinal IGF binding proteins: isolation and characterization. , 1991, Advances in experimental medicine and biology.

[513]  L. Giudice,et al.  Insulin-like growth factor binding proteins: structural and molecular relationships. , 1991, Growth factors.

[514]  M. Kramer,et al.  Impact of intrauterine growth retardation and body proportionality on fetal and neonatal outcome. , 1990, Pediatrics.

[515]  K. Hall,et al.  Insulin-like growth factors and their binding proteins. , 1990, Physiological reviews.

[516]  L. Adair Low birth weight and intrauterine growth retardation in Filipino infants. , 1989, Pediatrics.

[517]  F. Petraglia,et al.  Identification of immunoreactive neuropeptide-gamma in human placenta: localization, secretion, and binding sites. , 1989, Endocrinology.

[518]  M. Freemark,et al.  Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family. , 1989, The Journal of clinical investigation.

[519]  J. Morley,et al.  Endocrinology in aging. , 1988, Disease-a-month : DM.

[520]  S. Handwerger,et al.  Placental lactogen and growth hormone receptors in human fetal tissues: relationship to fetal plasma human placental lactogen concentrations and fetal growth. , 1988, The Journal of clinical endocrinology and metabolism.

[521]  A. Harding,et al.  Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies , 1988, Nature.

[522]  H. Friesen,et al.  Differential effects of estrogen and growth hormone on uterine and hepatic insulin-like growth factor I gene expression in the ovariectomized hypophysectomized rat. , 1988, Endocrinology.

[523]  R. Jennings,et al.  Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. , 1986, Circulation.

[524]  M. Binoux,et al.  Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competitive binding studies. , 1986, Analytical biochemistry.

[525]  R. Edwards,et al.  Electron spin resonance studies of intact mammalian skeletal muscle. , 1985, Biochimica et biophysica acta.

[526]  M D M Hadley,et al.  Intrauterine growth retardation , 1985 .

[527]  K. Gaskin,et al.  Pancreatic fluid secretion and protein hyperconcentration in cystic fibrosis. , 1985, The New England journal of medicine.

[528]  M. Rechler,et al.  Insulin-Like Growth Factor Receptors , 1985, Journal of Cell Science.

[529]  Z. Laron,et al.  Laron-type dwarfism (hereditary somatomedin deficiency): a review. , 1984, Ergebnisse der inneren Medizin und Kinderheilkunde.

[530]  K. Moore,et al.  Defective Oxidative Metabolism of Heart Mitochondria from Genetically Diabetic Mice , 1983, Diabetes.

[531]  G. Brooks,et al.  Free radicals and tissue damage produced by exercise. , 1982, Biochemical and biophysical research communications.

[532]  F. Sanger,et al.  Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome. , 1982, Journal of molecular biology.

[533]  E. Schoenle,et al.  Insulin-like growth factors I and II: some biological actions and receptor binding characteristics of two purified constituents of nonsuppressible insulin-like activity of human serum. , 1978, European journal of biochemistry.

[534]  E. Rinderknecht,et al.  The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. , 1978, The Journal of biological chemistry.

[535]  S. Glasser,et al.  Ontogeny and regulation of rat placental estrogen receptor. , 1978, Endocrinology.

[536]  E. Rinderknecht,et al.  Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[537]  H. Shwachman,et al.  Recurrent acute pancreatitis in patients with cystic fibrosis with normal pancreatic enzymes. , 1975, Pediatrics.

[538]  E. Page,et al.  Quantitative electron microscopic description of heart muscle cells. Application to normal, hypertrophied and thyroxin-stimulated hearts. , 1973, The American journal of cardiology.

[539]  W. Daughaday,et al.  Somatomedin: Proposed Designation for Sulphation Factor , 1972, Nature.

[540]  A. Pertzelan,et al.  Genetic pituitary dwarfism with high serum concentation of growth hormone--a new inborn error of metabolism? , 1966, Israel journal of medical sciences.

[541]  H. Sarles,et al.  Observations on 205 confirmed cases of acute pancreatitis, recurring pancreatitis, and chronic pancreatitis. , 1965, Gut.

[542]  E. Froesch,et al.  ANTIBODY-SUPPRESSIBLE AND NONSUPPRESSIBLE INSULIN-LIKE ACTIVITIES IN HUMAN SERUM AND THEIR PHYSIOLOGIC SIGNIFICANCE. AN INSULIN ASSAY WITH ADIPOSE TISSUE OF INCREASED PRECISION AND SPECIFICITY. , 1963, The Journal of clinical investigation.

[543]  D. Andersen CYSTIC FIBROSIS OF THE PANCREAS AND ITS RELATION TO CELIAC DISEASE: A CLINICAL AND PATHOLOGIC STUDY , 1938 .