Development of lipidoid-siRNA formulations for systemic delivery to the liver.
暂无分享,去创建一个
Michael S. Goldberg | Daniel G Anderson | Akin Akinc | Daniel G. Anderson | K. G. Rajeev | M. Manoharan | Michael S Goldberg | A. Akinc | I. Röhl | V. Koteliansky | R. Langer | J. R. Dorkin | June Qin | C. Gamba-Vitalo | M. Maier | K. Jayaprakash | M. Jayaraman | Elizaveta S. Leshchiner | Daniel G. Anderson | Christina Gamba-Vitalo | J Robert Dorkin | June Qin | Victor Koteliansky | Muthiah Manoharan | Muthusamy Jayaraman | Kallanthottathil G Rajeev | Robert Langer | K Narayanannair Jayaprakash | Ingo Röhl | Michael Goldberg | Elizaveta S Leshchiner | Martin Maier | C. Gamba‐Vitalo | Akin Akinc
[1] Keith Bowman,et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs , 2005, Nature Biotechnology.
[2] P. Cullis,et al. Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures. , 2001, Biochimica et biophysica acta.
[3] T. Ochiya,et al. Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[4] M. Bally,et al. Controlled destabilization of a liposomal drug delivery system enhances mitoxantrone antitumor activity , 1999, Nature Biotechnology.
[5] L. Palmer,et al. Lipid-based systems for the intracellular delivery of genetic drugs. , 1999, Molecular membrane biology.
[6] M. Bally,et al. The liposomal formulation of doxorubicin. , 2005, Methods in enzymology.
[7] M. Stoffel,et al. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs , 2007, Nature Biotechnology.
[8] M. Bally,et al. Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine. , 1998, Biochimica et biophysica acta.
[9] A. Judge,et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA , 2005, Nature Biotechnology.
[10] Darren H. Wakefield,et al. Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes , 2007, Proceedings of the National Academy of Sciences.
[11] Phillip A. Sharp,et al. The RNAi revolution , 2004, Nature.
[12] J. Heyes,et al. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[13] S. Lowe,et al. Tissue-specific and reversible RNA interference in transgenic mice , 2007, Nature Genetics.
[14] L. Medina-Kauwe,et al. Intracellular trafficking of nonviral vectors , 2005, Gene Therapy.
[15] L. Palmer,et al. Stabilized plasmid-lipid particles: construction and characterization , 1999, Gene Therapy.
[16] F. Szoka,et al. Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes* , 2003, Journal of Biological Chemistry.
[17] Matthias John,et al. RNAi-mediated gene silencing in non-human primates , 2006, Nature.
[18] E. Wisse,et al. The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer , 2008, Gene Therapy.
[19] Jayanth Panyam,et al. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. , 2003, Advanced drug delivery reviews.
[20] Feng Liu,et al. Development of non-viral vectors for systemic gene delivery. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[21] Tariq M Rana,et al. Design and creation of new nanomaterials for therapeutic RNAi. , 2007, ACS chemical biology.
[22] Mark E. Davis,et al. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. , 2005, Cancer research.
[23] N. Boyce. Trial halted after gene shows up in semen , 2001, Nature.
[24] Robert Langer,et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics , 2008, Nature Biotechnology.
[25] A. Klippel,et al. A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium , 2006, Gene Therapy.
[26] Matthias John,et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs , 2004, Nature.
[27] A. D. Fougerolles. Delivery vehicles for small interfering RNA in vivo. , 2008 .
[28] F. Szoka,et al. Lipid-based Nanoparticles for Nucleic Acid Delivery , 2007, Pharmaceutical Research.
[29] R. Wattiaux,et al. Endosomes, lysosomes: their implication in gene transfer. , 2000, Advanced drug delivery reviews.
[30] Judy Lieberman,et al. RNA interference targeting Fas protects mice from fulminant hepatitis , 2003, Nature Medicine.
[31] Judy Lieberman,et al. Interfering with disease: a progress report on siRNA-based therapeutics , 2007, Nature Reviews Drug Discovery.
[32] N. K. Jain,et al. Pharmaceutical and biomedical potential of surface engineered dendrimers. , 2007, Critical reviews in therapeutic drug carrier systems.
[33] E. Wagner,et al. Targeted nucleic acid delivery into tumors: new avenues for cancer therapy. , 2004, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[34] M. Hope,et al. Membrane perturbation and the mechanism of lipid-mediated transfer of DNA into cells. , 2000, Biochimica et biophysica acta.
[35] F. Dosio,et al. Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential , 2006, International journal of nanomedicine.
[36] D. Peer,et al. Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target , 2008, Science.
[37] Shubiao Zhang,et al. Cationic lipids and polymers mediated vectors for delivery of siRNA. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[38] Judy Lieberman,et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors , 2005, Nature Biotechnology.
[39] G. Cheon,et al. Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.