Diverse molecular functions of Hu proteins
暂无分享,去创建一个
[1] Alessandro Quattrone,et al. Post-transcriptional Regulation of Neuro-oncological Ventral Antigen 1 by the Neuronal RNA-binding Proteins ELAV* , 2008, Journal of Biological Chemistry.
[2] A. van Hoof,et al. Messenger RNA regulation: to translate or to degrade , 2008, The EMBO journal.
[3] W. Filipowicz,et al. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? , 2008, Nature Reviews Genetics.
[4] K. White,et al. The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization , 2008, Nucleic acids research.
[5] S. Tenenbaum,et al. Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis , 2008, The Journal of cell biology.
[6] B. Cisneros,et al. Myotonic dystrophy 1 in the nervous system: From the clinic to molecular mechanisms , 2008, Journal of neuroscience research.
[7] H. Lou,et al. Regulation of Neuron-Specific Alternative Splicing of Neurofibromatosis Type 1 Pre-mRNA , 2007, Molecular and Cellular Biology.
[8] A. F. Campese,et al. Notch and Ikaros: Not Only Converging Players in T Cell Leukemia , 2007, Cell cycle.
[9] Jun O. Liu,et al. RNA-Binding Proteins HuR and PTB Promote the Translation of Hypoxia-Inducible Factor 1α , 2007, Molecular and Cellular Biology.
[10] J. Port,et al. FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1. , 2007, RNA.
[11] G. M. Wilson,et al. Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences* , 2007, Journal of Biological Chemistry.
[12] J. Keene. RNA regulons: coordination of post-transcriptional events , 2007, Nature Reviews Genetics.
[13] C. Mahaffey,et al. Complex Seizure Disorder Caused by Brunol4 Deficiency in Mice , 2007, PLoS genetics.
[14] Kotb Abdelmohsen,et al. Posttranscriptional Orchestration of an Anti-Apoptotic Program by HuR , 2007, Cell cycle.
[15] E. Weeber,et al. Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD , 2007, Neurobiology of Learning and Memory.
[16] S. Jaffrey,et al. Function and translational regulation of mRNA in developing axons. , 2007, Seminars in cell & developmental biology.
[17] HuR binds to a single site on the C/EBPbeta mRNA of 3T3-L1 adipocytes. , 2007, Biochemical and biophysical research communications.
[18] A. F. Campese,et al. Notch3 and the Notch3‐upregulated RNA‐binding protein HuD regulate Ikaros alternative splicing , 2007, The EMBO journal.
[19] Kotb Abdelmohsen,et al. Phosphorylation of HuR by Chk2 regulates SIRT1 expression. , 2007, Molecular cell.
[20] Hua-Lin Zhou,et al. Hu Proteins Regulate Polyadenylation by Blocking Sites Containing U-rich Sequences* , 2007, Journal of Biological Chemistry.
[21] Lucie N. Hutchins,et al. Systematic variation in mRNA 3′-processing signals during mouse spermatogenesis , 2006, Nucleic acids research.
[22] A. Quattrone,et al. Defining a neuron: neuronal ELAV proteins , 2007, Cellular and Molecular Life Sciences.
[23] G. Luo,et al. A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators. , 2006, Molecular biology of the cell.
[24] Hua-Lin Zhou,et al. Role for Fox-1/Fox-2 in Mediating the Neuronal Pathway of Calcitonin/Calcitonin Gene-Related Peptide Alternative RNA Processing , 2006, Molecular and Cellular Biology.
[25] Robert M. Miura,et al. Prediction of mRNA polyadenylation sites by support vector machine , 2006, Bioinform..
[26] K. Riesbeck,et al. Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells , 2006, Nucleic acids research.
[27] N. Perrone-Bizzozero,et al. The RNA‐binding protein HuD: a regulator of neuronal differentiation, maintenance and plasticity , 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.
[28] W. Filipowicz,et al. Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress , 2006, Cell.
[29] J. Hauber,et al. Expression of CD83 Is Regulated by HuR via a Novel cis-Active Coding Region RNA Element* , 2006, Journal of Biological Chemistry.
[30] M. Gorospe,et al. Translational Control of Cytochrome c by RNA-Binding Proteins TIA-1 and HuR , 2006, Molecular and Cellular Biology.
[31] H. Yoshikawa,et al. CARM1 Regulates Proliferation of PC12 Cells by Methylating HuD , 2006, Molecular and Cellular Biology.
[32] N. Perrone-Bizzozero,et al. In vivo post‐transcriptional regulation of GAP‐43 mRNA by overexpression of the RNA‐binding protein HuD , 2006, Journal of neurochemistry.
[33] K. Riesbeck,et al. Wnt-5 a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells , 2006 .
[34] T. Cooper,et al. Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy. , 2006, Progress in molecular and subcellular biology.
[35] P. Pekala,et al. HuR, an RNA-binding protein, involved in the control of cellular differentiation. , 2006, In vivo.
[36] L. Paillard,et al. AU-rich elements and associated factors: are there unifying principles? , 2006, Nucleic acids research.
[37] P. Blackshear,et al. HuR as a negative posttranscriptional modulator in inflammation. , 2005, Molecular cell.
[38] M. Moore. From Birth to Death: The Complex Lives of Eukaryotic mRNAs , 2005, Science.
[39] P. Silver,et al. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain , 2005, BMC Developmental Biology.
[40] P. Pekala,et al. An Early Event in Adipogenesis, the Nuclear Selection of the CCAAT Enhancer-binding Protein β (C/EBPβ) mRNA by HuR and its Translocation to the Cytosol* , 2005, Journal of Biological Chemistry.
[41] E. Schuman,et al. Local translational control in dendrites and its role in long-term synaptic plasticity. , 2005, Journal of neurobiology.
[42] D. Lipscombe. Neuronal proteins custom designed by alternative splicing , 2005, Current Opinion in Neurobiology.
[43] P. Emanuel,et al. The ELAV RNA-stability factor HuR binds the 5′-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation , 2005, Nucleic acids research.
[44] M. Gorospe,et al. Antiapoptotic function of RNA‐binding protein HuR effected through prothymosin α , 2005, The EMBO journal.
[45] H. Okano,et al. The RNA-binding protein HuD regulates neuronal cell identity and maturation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[46] J. Lykke-Andersen,et al. Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. , 2005, Genes & development.
[47] M. Gorospe,et al. HuR: Post-Transcriptional Paths to Malignancy , 2005, RNA biology.
[48] P. Pekala,et al. An early event in adipogenesis, the nuclear selection of the CCAAT enhancer-binding protein {beta} (C/EBP{beta}) mRNA by HuR and its translocation to the cytosol. , 2005, The Journal of biological chemistry.
[49] P. Jin,et al. RNA and microRNAs in fragile X mental retardation , 2004, Nature Cell Biology.
[50] M. Gorospe,et al. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs , 2004, The EMBO journal.
[51] M. Hatzoglou,et al. Regulation of cationic amino acid transport: the story of the CAT-1 transporter. , 2004, Annual review of nutrition.
[52] M. Karin,et al. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. , 2004, Molecular cell.
[53] M. Gorospe,et al. Identification of a target RNA motif for RNA-binding protein HuR. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[54] D. Alkon,et al. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[55] Matthew L. Albert,et al. Paraneoplastic neurological degenerations: keys to tumour immunity , 2004, Nature Reviews Cancer.
[56] Christopher J. Lee,et al. Alternative splicing in the nervous system: an emerging source of diversity and regulation , 2003, Biological Psychiatry.
[57] M. Gorospe,et al. Regulation of Eotaxin Gene Expression by TNF-α and IL-4 Through mRNA Stabilization: Involvement of the RNA-Binding Protein HuR 1 , 2003, The Journal of Immunology.
[58] M. Hatzoglou,et al. Chronic Ethanol Exposure Increases the Binding of HuR to the TNFα 3′-Untranslated Region in Macrophages* , 2003, Journal of Biological Chemistry.
[59] H. Lou,et al. U1 snRNP-Dependent Function of TIAR in the Regulation of Alternative RNA Processing of the Human Calcitonin/CGRP Pre-mRNA , 2003, Molecular and Cellular Biology.
[60] L. O. Penalva,et al. RNA Binding Protein Sex-Lethal (Sxl) and Control of Drosophila Sex Determination and Dosage Compensation , 2003, Microbiology and Molecular Biology Reviews.
[61] K. Fukunaga,et al. Neurofibromatosis Type I Tumor Suppressor Neurofibromin Regulates Neuronal Differentiation via Its GTPase-activating Protein Function toward Ras* , 2003, Journal of Biological Chemistry.
[62] Myriam Gorospe,et al. Role of HuR in Skeletal Myogenesis through Coordinate Regulation of Muscle Differentiation Genes , 2003, Molecular and Cellular Biology.
[63] M. Gorospe,et al. RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[64] M. Gorospe. HuR in the Mammalian Genotoxic Response: Post-Transcriptional Multitasking , 2003, Cell cycle.
[65] A. Capobianco,et al. Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis. , 2003, Cancer cell.
[66] Tala Bakheet,et al. ARED 2.0: an update of AU-rich element mRNA database , 2003, Nucleic Acids Res..
[67] L. Hengst,et al. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. , 2002, Genes & development.
[68] D. Aswad,et al. Lipopolysaccharide-induced Methylation of HuR, an mRNA-stabilizing Protein, by CARM1* , 2002, The Journal of Biological Chemistry.
[69] M. Hatzoglou,et al. Nutritional Control of mRNA Stability Is Mediated by a Conserved AU-rich Element That Binds the Cytoplasmic Shuttling Protein HuR* , 2002, The Journal of Biological Chemistry.
[70] A. Shyu,et al. Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization , 2002, Molecular and Cellular Biology.
[71] E. Sakashita,et al. Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins. , 2002, Nucleic acids research.
[72] N. Perrone-Bizzozero,et al. Poly(A) Tail Length-dependent Stabilization of GAP-43 mRNA by the RNA-binding Protein HuD* , 2002, The Journal of Biological Chemistry.
[73] P. Blackshear,et al. Interactions of CCCH Zinc Finger Proteins with mRNA , 2002, The Journal of Biological Chemistry.
[74] M. Mann,et al. AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs , 2001, Cell.
[75] D. Alkon,et al. Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[76] A. Shyu,et al. Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.
[77] D. Mackey,et al. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). , 2001, Human molecular genetics.
[78] P. Blackshear,et al. Interactions of CCCH Zinc Finger Proteins with mRNA , 2001, The Journal of Biological Chemistry.
[79] Jack D. Keene,et al. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[80] N. Perrone-Bizzozero,et al. Overexpression of HuD Accelerates Neurite Outgrowth and Increases GAP-43 mRNA Expression in Cortical Neurons and Retinoic Acid-Induced Embryonic Stem Cells in Vitro , 2001, Experimental Neurology.
[81] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[82] K. Mahtani,et al. The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR , 2001, Molecular and Cellular Biology.
[83] Traci M. Tanaka Hall,et al. Structural basis for recognition of AU-rich element RNA by the HuD protein , 2001, Nature Structural Biology.
[84] J. A. Steitz,et al. HuR and mRNA stability , 2001, Cellular and Molecular Life Sciences CMLS.
[85] Tala Bakheet,et al. ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins , 2001, Nucleic Acids Res..
[86] N. Perrone-Bizzozero,et al. Overexpression of HuD, but Not of Its Truncated Form HuD I+II, Promotes GAP‐43 Gene Expression and Neurite Outgrowth in PC12 Cells in the Absence of Nerve Growth Factor , 2000, Journal of neurochemistry.
[87] N. Perrone-Bizzozero,et al. The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells. , 2000, Molecular biology of the cell.
[88] A. Koff,et al. A U-Rich Element in the 5′ Untranslated Region Is Necessary for the Translation of p27 mRNA , 2000, Molecular and Cellular Biology.
[89] NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C. , 2000, Nucleic acids research.
[90] Robert B Darnell,et al. Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability , 2000, Neuron.
[91] Myriam Gorospe,et al. HuR Regulates p21 mRNA Stabilization by UV Light , 2000, Molecular and Cellular Biology.
[92] W. Krone,et al. Tumor antigen HuR binds specifically to one of five protein-binding segments in the 3'-untranslated region of the neurofibromin messenger RNA. , 2000, Biochemical and biophysical research communications.
[93] E. Sakashita,et al. Cytoplasmic localization is required for the mammalian ELAV‐like protein HuD to induce neuronal differentiation , 1999, Genes to cells : devoted to molecular & cellular mechanisms.
[94] D. Gutmann,et al. Developmental regulation of a neuron‐specific neurofibromatosis 1 isoform , 1999, Annals of neurology.
[95] J. Keene,et al. ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells. , 1999, Genes & development.
[96] J. Keene. Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[97] H. Lou,et al. Mechanism of tissue-specific alternative RNA processing of the calcitonin CGRP gene. , 1999, Frontiers of hormone research.
[98] J. Steitz,et al. HNS, a nuclear-cytoplasmic shuttling sequence in HuR. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[99] A. Shyu,et al. RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein , 1998, The EMBO journal.
[100] A. Levy,et al. Hypoxic Stabilization of Vascular Endothelial Growth Factor mRNA by the RNA-binding Protein HuR* , 1998, The Journal of Biological Chemistry.
[101] H. Furneaux,et al. The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA. , 1997, Nucleic acids research.
[102] R. Darnell,et al. A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons , 1997, The Journal of Neuroscience.
[103] J. Steitz,et al. Identification of HuR as a protein implicated in AUUUA‐mediated mRNA decay , 1997, The EMBO journal.
[104] K. McGowan,et al. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes , 1997, Molecular and cellular biology.
[105] K. Yamamoto,et al. Target specificity of neuronal RNA-binding protein, Mel-N1: direct binding to the 3' untranslated region of its own mRNA. , 1996, Nucleic acids research.
[106] S. Cheng,et al. Purification and Properties of HuD, a Neuronal RNA-binding Protein (*) , 1996, The Journal of Biological Chemistry.
[107] Anne Wright,et al. Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein (*) , 1996, The Journal of Biological Chemistry.
[108] C. Y. Chen,et al. AU-rich elements: characterization and importance in mRNA degradation. , 1995, Trends in biochemical sciences.
[109] K. Georgopoulos,et al. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins , 1994, Molecular and cellular biology.
[110] C. Turck,et al. The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. , 1994, Molecular and cellular biology.
[111] S. Pulst,et al. Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development. , 1994, Developmental biology.
[112] J. Keene,et al. Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. , 1993, Molecular and cellular biology.
[113] K. Yao,et al. Gene elav of Drosophila melanogaster: a prototype for neuronal-specific RNA binding protein gene family that is conserved in flies and humans. , 1993, Journal of neurobiology.
[114] M. Wigler,et al. A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity , 1993, Molecular and cellular biology.
[115] C. Cordon-Cardo,et al. The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues. , 1992, The American journal of pathology.
[116] J. Henson,et al. HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal , 1991, Cell.
[117] L. Swanson,et al. Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene , 1987, Cell.
[118] S. Amara,et al. Alternative RNA processing: determining neuronal phenotype. , 1984, Science.