Antidiabetic activity of ethanolic leaf extract of Croton zambesicus Muell.(thunder plant) in alloxan diabetic rats

Antidiabetic activity of ethanolic leaf extract of Croton zambesicus Muell. Arg. was evaluated using alloxan-induced (150mg/kg) hyperglycaemic rats. The activity of the ethanolic leaf extract was compared with that of a reference drug Chlorpropamide. The Blood Glucose Levels were measured using glucometer. The extract produced a significant (P<0.01) reduction in BGL after a single dose of the extract and in prolonged treatment (for 7 days). The antidiabetic activity was comparable to that of the reference drug-chlorpropamide.

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