Analysis of Chlordecone [Kepone®] in Biological Specimens

We have investigated the toxicity and pharmacoklnetlcs of chlordecone (CD) In chemical workers poisoned with this organochlorine pesticide Ingredient. To achieve this objective we have developed a reliable and practical assay procedure for CD applicable to a variety of biological speclmens. A gas chromatographic method using an electron capture detector is presented together with s discussion of some of the analytical problems associated with this compound.

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