Asymptotically Optimal Amplifiers for the Moran Process

We study the Moran process as adapted by Lieberman, Hauert and Nowak. This is a model of an evolving population on a graph or digraph where certain individuals, called "mutants" have fitness r and other individuals, called non-mutants have fitness 1. We focus on the situation where the mutation is advantageous, in the sense that r>1. A family of digraphs is said to be strongly amplifying if the extinction probability tends to 0 when the Moran process is run on digraphs in this family. The most-amplifying known family of digraphs is the family of megastars of Galanis et al. We show that this family is optimal, up to logarithmic factors, since every strongly-connected n-vertex digraph has extinction probability Omega(n^(-1/2)). Next, we show that there is an infinite family of undirected graphs, called dense incubators, whose extinction probability is O(n^(-1/3)). We show that this is optimal, up to constant factors. Finally, we introduce sparse incubators, for varying edge density, and show that the extinction probability of these graphs is O(n/m), where m is the number of edges. Again, we show that this is optimal, up to constant factors.

[1]  Feller William,et al.  An Introduction To Probability Theory And Its Applications , 1950 .

[2]  S. Redner,et al.  Voter models on heterogeneous networks. , 2007, Physical review. E, Statistical, nonlinear, and soft matter physics.

[3]  Martin A. Nowak,et al.  Evolutionary dynamics on graphs , 2005, Nature.

[4]  Paul G. Spirakis,et al.  Natural models for evolution on networks , 2011, Theor. Comput. Sci..

[5]  Frank E. Grubbs,et al.  An Introduction to Probability Theory and Its Applications , 1951 .

[6]  Joel Friedman,et al.  A proof of Alon's second eigenvalue conjecture and related problems , 2004, ArXiv.

[7]  Maria J. Serna,et al.  Absorption time of the Moran process , 2013, Random Struct. Algorithms.

[8]  Devavrat Shah,et al.  Gossip Algorithms , 2009, Found. Trends Netw..

[9]  P. A. P. Moran,et al.  Random processes in genetics , 1958, Mathematical Proceedings of the Cambridge Philosophical Society.

[10]  Paul G. Spirakis,et al.  Strong Bounds for Evolution in Networks , 2013, ICALP.

[11]  T. Liggett,et al.  Stochastic Interacting Systems: Contact, Voter and Exclusion Processes , 1999 .

[12]  Larry Goldstein,et al.  Size biased couplings and the spectral gap for random regular graphs , 2015, 1510.06013.

[13]  G. Grimmett,et al.  The Critical Contact Process Dies Out , 1990 .

[14]  Paul G. Spirakis,et al.  On the fixation probability of superstars , 2013, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[15]  George Giakkoupis,et al.  Amplifiers and Suppressors of Selection for the Moran Process on Undirected Graphs , 2016, ArXiv.

[16]  Paul G. Spirakis,et al.  Approximating Fixation Probabilities in the Generalized Moran Process , 2011, Algorithmica.

[17]  B. Harshbarger An Introduction to Probability Theory and its Applications, Volume I , 1958 .

[18]  M. Nowak Evolutionary Dynamics: Exploring the Equations of Life , 2006 .

[19]  Leslie Ann Goldberg,et al.  Amplifiers for the Moran Process , 2016, ICALP.

[20]  Jeffrey E. Steif,et al.  Fixation Results for Threshold Voter Systems , 1993 .

[21]  Kathryn Fraughnaugh,et al.  Introduction to graph theory , 1973, Mathematical Gazette.

[22]  Rick Durrett,et al.  Some features of the spread of epidemics and information on a random graph , 2010, Proceedings of the National Academy of Sciences.

[23]  Christoph Hauert,et al.  Fixation probabilities on superstars, revisited and revised. , 2013, Journal of theoretical biology.