More phloroglucinols from Hypericum brasiliense

Three new phloroglucinols (hyperbrasilols B and C, and isohyperbrasilol B) have been isolated from a petrol extract of the leaves and flowers of Hypericum brasiliense. Their structures were established by spectroscopic methods including two-dimensional-NMR heteronuclear correlations. EI and D/Cl-mass spectral, NMR, IR and UV data are reported. All three phloroglucinols were antibacterial against Bacillus subtilis in a TLC bioautographic assay.