Latest developments in the pathogenesis and treatment of celiac disease.

[1]  Giuseppe Iacono,et al.  Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines , 2006, Scandinavian journal of gastroenterology.

[2]  Cisca Wijmenga,et al.  Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect , 2005, Nature Genetics.

[3]  V. Raia,et al.  Unexpected role of surface transglutaminase type II in celiac disease. , 2005, Gastroenterology.

[4]  E. Bergseng,et al.  Refining the Rules of Gliadin T Cell Epitope Binding to the Disease-Associated DQ2 Molecule in Celiac Disease: Importance of Proline Spacing and Glutamine Deamidation1 , 2005, The Journal of Immunology.

[5]  G. Corazza,et al.  Coeliac disease , 2005, Journal of Clinical Pathology.

[6]  M. Rewers,et al.  Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. , 2005, JAMA.

[7]  L. Greco,et al.  GENETIC RISK OF FIRST DEGREE RELATIVES OF COELIAC PATIENTS: PG5-16 , 2005 .

[8]  C. Khosla,et al.  Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2. , 2005, Chemistry & biology.

[9]  C. Khosla,et al.  Future therapeutic options for celiac disease , 2005, Nature Clinical Practice Gastroenterology &Hepatology.

[10]  C. Gianfrani,et al.  Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa , 2004, Gut.

[11]  P. Allen Guidelines for the diagnosis and treatment of celiac disease in children. , 2004 .

[12]  Seiamak Bahram,et al.  A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. , 2004, Immunity.

[13]  L. Sollid Intraepithelial lymphocytes in celiac disease: license to kill revealed. , 2004, Immunity.

[14]  H. Kolb,et al.  Wheat Gluten Causes Dendritic Cell Maturation and Chemokine Secretion1 , 2004, The Journal of Immunology.

[15]  E. Bergseng,et al.  Antigen Presentation to Celiac Lesion-Derived T Cells of a 33-Mer Gliadin Peptide Naturally Formed by Gastrointestinal Digestion1 , 2004, The Journal of Immunology.

[16]  I. Korponay-Szabó,et al.  In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies , 2004, Gut.

[17]  E. Lindberg,et al.  Oats to children with newly diagnosed coeliac disease: a randomised double blind study , 2004, Gut.

[18]  L. Greco,et al.  Sourdough Bread Made from Wheat and Nontoxic Flours and Started with Selected Lactobacilli Is Tolerated in Celiac Sprue Patients , 2004, Applied and Environmental Microbiology.

[19]  H. Wieser,et al.  Coeliac disease: in vivo toxicity of the putative immunodominant epitope , 2003, Gut.

[20]  M. Babron,et al.  Meta and pooled analysis of European coeliac disease data , 2003, European Journal of Human Genetics.

[21]  E. Méndez,et al.  Oats induced villous atrophy in coeliac disease , 2003, Gut.

[22]  F. Koning,et al.  The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[23]  C. Wijmenga,et al.  A major non-HLA locus in celiac disease maps to chromosome 19. , 2003, Gastroenterology.

[24]  R. Troncone,et al.  Enhanced Expression of Interferon Regulatory Factor-1 in the Mucosa of Children with Celiac Disease , 2003, Pediatric Research.

[25]  V. Raia,et al.  Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease , 2003, The Lancet.

[26]  B. Lie,et al.  Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles , 2003, Immunogenetics.

[27]  Jorma Ilonen,et al.  Prevalence of Celiac disease among children in Finland. , 2003, The New England journal of medicine.

[28]  K. Kaukinen,et al.  Intraepithelial lymphocytes in celiac disease. , 2003 .

[29]  R. Troncone,et al.  Constitutive activation of the signal transducer and activator of transcription pathway in celiac disease lesions. , 2003, The American journal of pathology.

[30]  L. Greco,et al.  HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease. , 2003, Human immunology.

[31]  A. Sette,et al.  Celiac Disease Association with CD8+ T Cell Responses: Identification of a Novel Gliadin-Derived HLA-A2-Restricted Epitope1 , 2003, The Journal of Immunology.

[32]  S. Virgiliis,et al.  Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function , 2003, Gut.

[33]  Lu Shan,et al.  Structural Basis for Gluten Intolerance in Celiac Sprue , 2002, Science.

[34]  P. Roepstorff,et al.  Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues. , 2002, Gastroenterology.

[35]  L. Sollid Coeliac disease: dissecting a complex inflammatory disorder , 2002, Nature Reviews Immunology.

[36]  F. Paparo,et al.  Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ , 2002, Gut.

[37]  J. Drijfhout,et al.  The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. , 2002, Gastroenterology.

[38]  A. Ivarsson,et al.  Breast-feeding protects against celiac disease. , 2002, The American journal of clinical nutrition.

[39]  L. Greco,et al.  The first large population based twin study of coeliac disease , 2002, Gut.

[40]  J. Drijfhout,et al.  Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease , 2002, The Journal of experimental medicine.

[41]  V. Kosma,et al.  No harm from five year ingestion of oats in coeliac disease , 2002, Gut.

[42]  E. Tongiorgi,et al.  Molecular Dissection of the Tissue Transglutaminase Autoantibody Response in Celiac Disease1 , 2001, The Journal of Immunology.

[43]  A. Fasano,et al.  Human zonulin, a potential modulator of intestinal tight junctions. , 2000, Journal of cell science.

[44]  D. Schuppan,et al.  Current concepts of celiac disease pathogenesis. , 2000, Gastroenterology.

[45]  G. Coppa,et al.  Compliance with gluten-free diet in adolescents with screening-detected celiac disease: a 5-year follow-up study. , 2000, The Journal of pediatrics.

[46]  R. Jian,et al.  Selective expansion of intraepithelial lymphocytes expressing the HLA-E–specific natural killer receptor CD94 in celiac disease☆☆☆ , 2000, Gastroenterology.

[47]  A. Fasano,et al.  Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease , 2000, The Lancet.

[48]  D. Branski,et al.  Are intraepithelial lymphocytes in celiac mucosa responsible for inducing programmed cell death (apoptosis) in enterocytes? Histochemical demonstration of perforins in cytoplasmic granules of intraepithelial lymphocytes. , 1998, Journal of pediatric gastroenterology and nutrition.

[49]  K. Lundin,et al.  Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease. , 1998, Gastroenterology.

[50]  R. Troncone,et al.  Celiac disease: a reappraisal. , 1998, The Journal of pediatrics.

[51]  J. Bach,et al.  CTLA-4 gene polymorphism is associated with predisposition to coeliac disease , 1998, Gut.

[52]  A. Fasano Modulation of intestinal permeability: an innovative method of oral drug delivery for the treatment of inherited and acquired human diseases. , 1998, Molecular genetics and metabolism.

[53]  J. Schulzke,et al.  Epithelial Tight Junction Structure in the Jejunum of Children with Acute and Treated Celiac Sprue , 1998, Pediatric Research.

[54]  S. Virgiliis,et al.  Genome search in celiac disease. , 1998, American journal of human genetics.

[55]  K. Lundin,et al.  Autoantibodies in coeliac disease: tissue transglutaminase—guilt by association? , 1997, Gut.

[56]  L. Leach,et al.  Structure and permeability of human placental microvasculature , 1997, Microscopy research and technique.

[57]  S. Lewis,et al.  Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion. , 1997, Gastroenterology.

[58]  D. Schuppan,et al.  Identification of tissue transglutaminase as the autoantigen of celiac disease , 1997, Nature Medicine.

[59]  J. Tschopp,et al.  Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways , 1994, Nature.

[60]  K. Lundin,et al.  Wheat peptide challenge in coeliac disease , 1994, The Lancet.

[61]  J. Madara,et al.  Structural abnormalities of jejunal epithelial cell membranes in celiac sprue. , 1980, Laboratory investigation; a journal of technical methods and pathology.

[62]  E. Seidman,et al.  Guideline for the Diagnosis and Treatment of Celiac Disease in Children : Recommendations of the North American Society for Pediatric Gastroenterology , Hepatology and Nutrition , 2004 .

[63]  H Sievänen,et al.  Celiac disease without villous atrophy: revision of criteria called for. , 2001, Digestive diseases and sciences.