论文信息 - Steady state inactivation of sodium permeability in myelinated nerve fibres of Xenopus laevis

Steady state inactivation of sodium permeability in myelinated nerve fibres of Xenopus laevis

Previous experiments (Dodge & Frankenhaeuser, 1958, 1959) have shown that the permeability changes at the node of Ranvier are qualitatively similar to those in the squid giant axon (Hodgkin & Huxley, 1952a-d). When the membrane is depolarized the sodium permeability rises rapidly to a peak and then falls as a result of inactivation. The aim of the present paper is to determine the relation between membrane potential and the extent to which the sodium conducting system is inactivated or refractory.

B. Frankenhaeuser | B FRANKENHAEUSER

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