Effects of age increase on hepatic expression and activity of cytochrome P450 in male C57BL/6 mice

[1]  Hyoung‐Chin Kim,et al.  Mitral and Tufted Cells Are Potential Cellular Targets of Nitration in the Olfactory Bulb of Aged Mice , 2013, PloS one.

[2]  K. Kang,et al.  Age-related changes in hepatic expression and activity of cytochrome P450 in male rats , 2010, Archives of Toxicology.

[3]  A. Owen,et al.  The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC , 2009, British journal of pharmacology.

[4]  J. Chovan,et al.  Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats , 2007, Xenobiotica; the fate of foreign compounds in biological systems.

[5]  P. Calderon,et al.  The effect of ageing on cytochrome p450 enzymes: consequences for drug biotransformation in the elderly. , 2007, Current medicinal chemistry.

[6]  R. Novak,et al.  The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression. , 2007, Pharmacology & therapeutics.

[7]  R. de Kanter,et al.  Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction , 2006, Expert opinion on drug metabolism & toxicology.

[8]  B. Walther,et al.  CHARACTERIZATION OF MICROSOMAL CYTOCHROME P450-DEPENDENT MONOOXYGENASES IN THE RAT OLFACTORY MUCOSA , 2005, Drug Metabolism and Disposition.

[9]  N. Bunce,et al.  Inhibition of CYP 1A2–dependent MROD activity in rat liver microsomes: An explanation of the hepatic sequestration of a limited subset of halogenated aromatic hydrocarbons , 2003, Environmental toxicology.

[10]  Kaoru Kobayashi,et al.  Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat. , 2002, Biochemical pharmacology.

[11]  D. Greenblatt,et al.  Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level. , 2000, Journal of pharmacological and toxicological methods.

[12]  K. Doi,et al.  Hepatic cytochrome P450 and flavin-containing monooxygenase in male Nts:Mini rat, a transgenic rat carrying antisense RNA transgene for rat growth hormone. , 1999, Toxicology letters.

[13]  I. Leclercq,et al.  Estimation of chlorzoxazone hydroxylase activity in liver microsomes and of the plasma pharmacokinetics of chlorzoxazone by the same high-performance liquid chromatographic method. , 1998, Journal of chromatography. A.

[14]  R. Weaver,et al.  Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. , 1994, Biochemical pharmacology.

[15]  S. Imaoka,et al.  Age-dependent expression of cytochrome P-450s in rat liver. , 1991, Biochimica et biophysica acta.

[16]  T. Kamataki,et al.  Four Forms of Cytochrome P‐450 in Human Fetal Liver: Purification and Their Capacity to Activate Promutagens , 1991, Japanese journal of cancer research : Gann.

[17]  C. Omiecinski,et al.  Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. , 1990, Cancer research.

[18]  J. Schenkman,et al.  Physiological and pathophysiological alterations in rat hepatic cytochrome P-450. , 1989, Drug metabolism reviews.

[19]  T. Kamataki,et al.  Postnatal development of constitutive forms of cytochrome P-450 in liver microsomes of male and female rats. , 1984, Biochemical pharmacology.

[20]  R. Estabrook,et al.  The measurement of difference spectra: application to the cytochromes of microsomes. , 1978, Methods in enzymology.

[21]  H. Strobel,et al.  Purification and properties of NADPH-cytochrome P-450 reductase. , 1978, Methods in enzymology.

[22]  T. Omura,et al.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE. , 1964, The Journal of biological chemistry.

[23]  T. Omura,et al.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES. , 1964, The Journal of biological chemistry.

[24]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.