The effects of Lycium barbarum water extract and fish collagen on milk proteolysis and in vitro angiotensin I‐converting enzyme inhibitory activity of yogurt

Plain and Lycium barbarum yogurt were made in the presence and absence of fish collagen. Yogurt samples were analyzed for acidification, milk protein proteolysis, angiotensin I‐converting enzyme (ACE) inhibitory activity, and sensory evaluation during refrigerated storage for up to 21 days. The o‐phthaldialdehyde peptides amount of L. barbarum yogurt both in the presence and absence of fish collagen were significantly increased during 14 days of storage. SDS‐PAGE showed improvement in whey proteins degradation of L. barbarum yogurt with/without fish collagen after 3 weeks of storage. L. barbarum yogurt in absence of fish collagen was acting as a great ACE inhibitor reached up to 85% on day 7 of storage. The incorporation of L. barbarum and/or fish collagen affected to a small extent the overall sensory characteristics of yogurt. Yogurt supplemented with L. barbarum and/or fish collagen may lead to the improvement in the production and formulation of yogurt differing in their anti‐ACE activity.

[1]  Sik Yoon,et al.  Marine Collagen as A Promising Biomaterial for Biomedical Applications , 2019, Marine drugs.

[2]  Jingyi Zhang,et al.  Collagen Peptide Upregulates Osteoblastogenesis from Bone Marrow Mesenchymal Stem Cells through MAPK- Runx2 , 2019, Cells.

[3]  A. Koukkou,et al.  Major ecological shifts within the dominant nonstarter lactic acid bacteria in mature Greek Graviera cheese as affected by the starter culture type. , 2019, International journal of food microbiology.

[4]  Hongxia Zhang,et al.  Goji Berries as a Potential Natural Antioxidant Medicine: An Insight into Their Molecular Mechanisms of Action , 2019, Oxidative medicine and cellular longevity.

[5]  B. Salehi,et al.  Therapeutic Potential of Alpha- and Beta-Pinene A Miracle Gift of Nature , 2019 .

[6]  Y. K. Erdem,et al.  Interactions between milk proteins and polyphenols: Binding mechanisms, related changes, and the future trends in the dairy industry , 2018 .

[7]  A. B. Shori,et al.  Effect of the addition of phytomix-3+ mangosteen on antioxidant activity, viability of lactic acid bacteria, type 2 diabetes key-enzymes, and sensory evaluation of yogurt , 2018, LWT.

[8]  G. Adiletta,et al.  Effect of a physical pre-treatment and drying on carotenoids of goji berries (Lycium barbarum L.) , 2018, LWT.

[9]  S. Stacker,et al.  Emerging Roles for VEGF-D in Human Disease , 2018, Biomolecules.

[10]  X. Lai,et al.  Effects of Lycium barbarum polysaccharides with different molecular weights on function of RAW264.7 macrophages , 2018 .

[11]  Wenwen Wang,et al.  Characterization of the Lycium barbarum fruit transcriptome and development of EST-SSR markers , 2017, PloS one.

[12]  Wanpeng Xi,et al.  Functional constituents and antioxidant activities of eight Chinese native goji genotypes. , 2016, Food chemistry.

[13]  A. Zotos,et al.  Fish Processing By-Products as a Potential Source of Gelatin: A Review , 2016 .

[14]  S. Mohapatra,et al.  Milk derived bioactive peptides and their impact on human health – A review , 2015, Saudi journal of biological sciences.

[15]  A. B. Shori The potential applications of probiotics on dairy and non-dairy foods focusing on viability during storage , 2015 .

[16]  Huixia Lu,et al.  Practical Application of Antidiabetic Efficacy of Lycium barbarum Polysaccharide in Patients with Type 2 Diabetes , 2015, Medicinal chemistry (Shariqah (United Arab Emirates)).

[17]  R. Amarowicz,et al.  Effect of Interaction Phenolic Compounds with Milk Proteins on Cell Line , 2014 .

[18]  Wenjun Liu,et al.  Angiotensin-converting enzyme inhibitory activity of Lactobacillus helveticus strains from traditional fermented dairy foods and antihypertensive effect of fermented milk of strain H9. , 2014, Journal of dairy science.

[19]  A. B. Shori,et al.  Viability of Lactic Acid Bacteria, Antioxidant Activity and In Vitro Inhibition of Angiotensin-I-Converting Enzyme of Lycium barbarum Yogurt , 2014 .

[20]  A. B. Shori Antioxidant activity and viability of lactic acid bacteria in soybean-yogurt made from cow and camel milk , 2013 .

[21]  A. B. Shori,et al.  The effects of fish collagen on the proteolysis of milk proteins, ACE inhibitory activity and sensory evaluation of plain- and Allium sativum-yogurt , 2013 .

[22]  A. B. Shori,et al.  Antioxidant activity and inhibition of key enzymes linked to type-2 diabetes and hypertension by Azadirachta indica-yogurt , 2013 .

[23]  Ksenija Uroić,et al.  Proteolytic activity of probiotic strain Lactobacillus helveticus M92. , 2013, Anaerobe.

[24]  George Q. Li,et al.  Traditional Chinese medicines , 2004, Reactions Weekly.

[25]  A. Saboury,et al.  Biological activity of camel milk casein following enzymatic digestion. , 2011, The Journal of dairy research.

[26]  Shabboo Amirdivani,et al.  Changes in Yogurt Fermentation Characteristics, And Antioxidant Potential And In Vitro Inhibition Of Angiotensin-1 Converting Enzyme Upon The Inclusion Of Peppermint, Dill And Basil , 2011 .

[27]  O. Potterat Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. , 2010, Planta medica.

[28]  Heping Zhang,et al.  A survey on chemical and microbiological composition of kurut, naturally fermented yak milk from Qinghai in China , 2008 .

[29]  E. Ritz Heart and kidney: fatal twins? , 2006, The American journal of medicine.

[30]  M. Gobbetti,et al.  Proteolytic activity and reduction of gliadin‐like fractions by sourdough lactobacilli , 2005, Journal of applied microbiology.

[31]  Z. Dimitrov,et al.  Characterization of Lactobacillus helveticus strains isolated from Bulgarian yoghurt, cheese, plants and human faecal samples by sodium dodecilsulfate polyacrylamide gel electrophoresis of cell-wall proteins, ribotyping and pulsed field gel fingerprinting. , 2005 .

[32]  M. Sitohy,et al.  PROTEOLYSIS OF EWE'S CASEINS AND WHEY PROTEINS DURING FERMENTATION OF YOGURT AND STORAGE. EFFECT OF THE STARTERS USED , 2004 .

[33]  A. Aly,et al.  Carrot Yoghurt : Sensory, Chemical, Microbiological Properties and Consumer Acceptance , 2004 .

[34]  W. Verstraete,et al.  The impact of fermentation and in vitro digestion on the formation of angiotensin-I-converting enzyme inhibitory activity from pea and whey protein. , 2003, Journal of dairy science.

[35]  Nagendra P. Shah,et al.  Proteolytic profiles of yogurt and probiotic bacteria , 2000 .