Asian-Indians: a review of coronary artery disease in this understudied cohort in the United States.

Coronary artery disease (CAD) is a major cause of cardiovascular death worldwide. Prevalence of CAD is highly variable among different races. Asian Indians have been noted to have the highest CAD rates and the conventional risk factors fail to explain this difference completely. Asian Indians constitute a fifth of the global population, and the higher rates of CAD in this population constitute a major health challenge. There have been studies in the early 2000s that investigate the risk factors in this population; however, very few studies have been done since then that explore the higher CAD rates in Asian Indians. This is a comprehensive and current review of the known risk factors for CAD in Asian Indians and strategies physicians should consider relieving this burden.

[1]  W. J. Steinberg,et al.  Decline in the ischaemic heart disease mortality rates of South Africans, 1968-1985. , 1988, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[2]  J E Keil,et al.  Socioeconomic factors and cardiovascular disease: a review of the literature. , 1993, Circulation.

[3]  Ruth McPherson,et al.  Genetics of Coronary Artery Disease. , 2016, Circulation research.

[4]  Reddy Ks,et al.  Cardiovascular diseases in India. , 1993, World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales.

[5]  D. Absher,et al.  Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls , 2010, Circulation. Cardiovascular genetics.

[6]  E. Raftery,et al.  First myocardial infarctions in Asian and white men. , 1989, BMJ.

[7]  M. C. Reid,et al.  Attitudes of Asian‐Indian Hindus Toward End‐of‐Life Care , 2005, Journal of the American Geriatrics Society.

[8]  Satyavan Sharma,et al.  Prevalence of coronary heart disease and coronary risk factors in an urban population of Rajasthan. , 1995, Indian heart journal.

[9]  Hisashi Adachi,et al.  Inflammation, atherosclerosis, and coronary artery disease. , 2005, The New England journal of medicine.

[10]  R. Virmani,et al.  Sex differences in coronary artery disease: pathological observations. , 2015, Atherosclerosis.

[11]  T. Assimes,et al.  Call to action: cardiovascular disease in Asian Americans: a science advisory from the American Heart Association. , 2010, Circulation.

[12]  M. Rani,et al.  Tobacco use in India: prevalence and predictors of smoking and chewing in a national cross sectional household survey , 2003, Tobacco control.

[13]  D. Himmelstein,et al.  Diabetes and cardiovascular disease among asian indians in the united states , 2005, Journal of General Internal Medicine.

[14]  J. Delva,et al.  Social capital and smoking among Asian American men: an exploratory study. , 2012, American journal of public health.

[15]  Alan D. Lopez,et al.  Alcohol consumption and mortality among middle-aged and elderly U.S. adults. , 1997, The New England journal of medicine.

[16]  Talicia Tarver,et al.  HEART DISEASE AND STROKE STATISTICS–2014 UPDATE: A REPORT FROM THE AMERICAN HEART ASSOCIATION , 2014 .

[17]  N. Nanda,et al.  Prevalence of diabetes mellitus and related conditions in Asian Indians living in the United States. , 2004, The American journal of cardiology.

[18]  N. Zane,et al.  Confronting critical health issues of Asian and Pacific Islander Americans , 1994 .

[19]  S. Yusuf MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals: a randomised placebo-controlled trial. Commentary , 2002 .

[20]  GordonW. Duff PEPTIDE REGULATORY FACTORS IN NON-MALIGNANT DISEASE , 1989, The Lancet.

[21]  C. Caspersen,et al.  Physical activity and the incidence of coronary heart disease. , 1987, Annual review of public health.

[22]  A. Adelstein,et al.  LESSONS FROM THE STUDY OF IMMIGRANT MORTALITY , 1984, The Lancet.

[23]  Christopher M O'Connor,et al.  Treatment of Hypertension in Patients With Coronary Artery Disease: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension. , 2015, Journal of the American College of Cardiology.

[24]  K. Hughes,et al.  Cardiovascular diseases in Chinese, Malays, and Indians in Singapore. I. Differences in mortality. , 1990, Journal of epidemiology and community health.

[25]  AndrewJ. S. Coats MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial , 2002, The Lancet.

[26]  L. Appel,et al.  Low serum cholesterol and haemorrhagic stroke in men: Korea Medical Insurance Corporation Study , 2001, The Lancet.

[27]  A. Klatsky,et al.  The risk of hospitalization for ischemic heart disease among Asian Americans in northern California. , 1994, American journal of public health.

[28]  M. Legato Coronary artery disease in women. , 1996, International journal of fertility and menopausal studies.

[29]  S. Yusuf,et al.  Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. , 2007, JAMA.

[30]  D. Kromhout,et al.  Cardiovascular risk factors in relation to educational level in 36 000 men and women in The Netherlands. , 1996, European heart journal.

[31]  G Premalatha,et al.  Coronary Artery Disease Prevalence of Coronary Artery Disease and Its Relationship to Lipids in a Selected Population in South India The Chennai Urban Population Study (CUPS No. 5) , 2001 .

[32]  G. Heath,et al.  Effects of 12 Months of Intense Exercise Training on Ischemic ST‐segment Depression in Patients with Coronary Artery Disease , 1981, Circulation.

[33]  J. Danesh,et al.  Large-scale association analysis identifies new risk loci for coronary artery disease , 2013 .

[34]  J. Genest Dyslipidemia and coronary artery disease. , 2000, Canadian Journal of Cardiology.

[35]  Soo-Ho Choi,et al.  Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity , 2011, Circulation research.

[36]  S. Mehta Relationship between acculturation and mental health for Asian Indian immigrants in the United States. , 1998, Genetic, social, and general psychology monographs.

[37]  J. Killian,et al.  Coronary atherosclerosis in diabetes mellitus: a population-based autopsy study. , 2002, Journal of the American College of Cardiology.

[38]  John F. Peden,et al.  Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour , 2011, Human molecular genetics.

[39]  Michelle A. Mathiason,et al.  Metabolic syndrome and coronary heart disease equivalent conditions in predicting cardiovascular events in young to middle-aged adults. , 2006, Journal of the cardiometabolic syndrome.

[40]  Cigarette Smoking as a Risk Factor of Coronary Artery Disease and its Effects on Platelet Function , 2004, Tobacco induced diseases.

[41]  R. Bhopal,et al.  Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study , 1999, BMJ.

[42]  S. Yusuf,et al.  Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study , 2004, The Lancet.

[43]  V. Montori,et al.  Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies , 2006, The Lancet.

[44]  G. Lip,et al.  Ethnic differences in hypertension and blood pressure control in the UK. , 2001, QJM : monthly journal of the Association of Physicians.

[45]  S. Fortmann,et al.  Coronary heart disease mortality for six ethnic groups in California, 1990-2000. , 2004, Annals of epidemiology.

[46]  E. Enas,et al.  Comparison of levels of large and small high-density lipoprotein cholesterol in Asian Indian men compared with Caucasian men in the Framingham Offspring Study. , 2004, The American journal of cardiology.

[47]  V. Mohan,et al.  High prevalence of diabetes and impaired glucose tolerance in India: National Urban Diabetes Survey , 2001, Diabetologia.

[48]  P. Malhotra,et al.  Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America. , 1996, Indian heart journal.

[49]  K. Reddy,et al.  Cardiovascular diseases in India. , 1993, World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales.

[50]  N. Sattar,et al.  Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians , 2001, International Journal of Obesity.

[51]  John C Chambers,et al.  Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men , 2000, The Lancet.

[52]  Peter T.Kuo Dyslipidemia and coronary artery disease , 1994 .

[53]  Lisa Lollock,et al.  The foreign born population in the United States , 2001 .

[54]  N. Ganguly,et al.  Premature Coronary Artery Disease in Indians and its Associated Risk Factors , 2005, Vascular health and risk management.

[55]  J. Mehta,et al.  Malignant coronary artery disease in young asian indians: Thoughts on pathogenesis, prevention, and therapy , 1995, Clinical cardiology.

[56]  E. Enas,et al.  Coronary Artery Disease In Asian Indians: An Update And Review , 2001 .

[57]  S. Hoerr,et al.  Relationship of diet, abdominal obesity, and physical activity to plasma lipoprotein levels in Asian Indian physicians residing in the United States. , 1996, Journal of the American Dietetic Association.

[58]  T. Mcguire,et al.  Health Insurance Coverage for Vulnerable Populations: Contrasting Asian Americans and Latinos in the United States , 2006, Inquiry : a journal of medical care organization, provision and financing.

[59]  R. Keefe,et al.  Barriers to Healthcare Among Asian Americans , 2010, Social work in public health.

[60]  J. Nordstrom,et al.  Regulation of HMG-CoA reductase. , 1976, Advances in lipid research.

[61]  Christopher M O'Connor,et al.  Treatment of Hypertension in Patients With Coronary Artery Disease: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Society of Hypertension , 2015 .

[62]  Alan D. Lopez,et al.  Global and regional cause-of-death patterns in 1990. , 1994, Bulletin of the World Health Organization.

[63]  S. Yusuf,et al.  Coronary Artery Disease in Asian Indians: Prevalence and Risk Factors. , 1993, Asian American and Pacific Islander journal of health.

[64]  D. Kromhout,et al.  Prevention of coronary heart disease by diet and lifestyle: evidence from prospective cross-cultural, cohort, and intervention studies. , 2002, Circulation.

[65]  B. Shah,et al.  Tobacco smoking in India: prevalence, quit-rates and respiratory morbidity. , 2006, The Indian journal of chest diseases & allied sciences.

[66]  R. Balarajan,et al.  Ethnic differences in mortality from ischaemic heart disease and cerebrovascular disease in England and Wales. , 1991, BMJ.

[67]  K. Hughes,et al.  Risk factors and incident coronary heart disease in Chinese, Malay and Asian Indian males: the Singapore Cardiovascular Cohort Study. , 2001, International journal of epidemiology.

[68]  G. Miller,et al.  Ethnicity and other characteristics predictive of coronary heart disease in a developing community: principal results of the St James Survey, Trinidad. , 1989, International journal of epidemiology.