Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal

[1]  R. Brooks.  Commentary: locating the restriction point , 2023, Cell Division.

[2]  R. Brooks.  Cell Cycle Commitment and the Origins of Cell Cycle Variability , 2021, Frontiers in Cell and Developmental Biology.

[3]  S. Cappell,et al.  Cell cycle inertia underlies a bifurcation in cell fates after DNA damage , 2021, Science Advances.

[4]  Brooks Taylor,et al.  Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle , 2020, Cell reports.

[5]  Paul F. Lang,et al.  Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B , 2020, The EMBO journal.

[6]  Chengzhe Tian,et al.  Temporal integration of mitogen history in mother cells controls proliferation of daughter cells , 2020, Science.

[7]  T. Meyer,et al.  Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1. , 2019, Molecular cell.

[8]  J. Skotheim,et al.  A Precise Cdk Activity Threshold Determines Passage through the Restriction Point. , 2018, Molecular cell.

[9]  S. Spencer,et al.  Irreversible APCCdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry , 2016, Cell.

[10]  T. Schroeder,et al.  Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysis , 2016, Scientific Reports.

[11]  M. Nakanishi,et al.  Necessary and sufficient role for a mitosis skip in senescence induction. , 2014, Molecular cell.

[12]  Sabrina L. Spencer,et al.  The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit , 2013, Cell.

[13]  M. Rosner,et al.  An integrated view of cyclin E function and regulation , 2012, Cell cycle.

[14]  M. West,et al.  Origin of bistability underlying mammalian cell cycle entry , 2011, Molecular systems biology.

[15]  Gürol M. Süel,et al.  Temporal competition between differentiation programs determines cell fate choice , 2011, Molecular systems biology.

[16]  C. Hagemeier,et al.  p53- and p21-dependent premature APC/C–Cdh1 activation in G2 is part of the long-term response to genotoxic stress , 2010, Oncogene.

[17]  Tae J. Lee,et al.  A bistable Rb–E2F switch underlies the restriction point , 2008, Nature Cell Biology.

[18]  Atsushi Miyawaki,et al.  Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression , 2008, Cell.

[19]  A. Zetterberg,et al.  Single cell analysis of G1 check points-the relationship between the restriction point and phosphorylation of pRb. , 2005, Experimental cell research.

[20]  Eduardo Sontag,et al.  Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2 , 2003, Nature Cell Biology.

[21]  John J. Tyson,et al.  Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[22]  Mikhail V. Blagosklonny,et al.  The Restriction Point of the Cell Cycle , 2002, Cell cycle.

[23]  S. Elledge,et al.  Phosphorylation-Dependent Ubiquitination of Cyclin E by the SCFFbw7 Ubiquitin Ligase , 2001, Science.

[24]  R. Weinberg,et al.  The restriction point and control of cell proliferation. , 1997, Current opinion in cell biology.

[25]  C. Sherr.  Cancer Cell Cycles , 1996, Science.

[26]  S. Reed,et al.  Activation of cyclin E/CDK2 is coupled to site‐specific autophosphorylation and ubiquitin‐dependent degradation of cyclin E. , 1996, The EMBO journal.

[27]  L. J. Veer,et al.  E2F-5, a new E2F family member that interacts with p130 in vivo , 1995, Molecular and cellular biology.

[28]  D. Livingston,et al.  Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. , 1995, Genes & development.

[29]  J. Lawrence,et al.  E2F-4, a new member of the E2F transcription factor family, interacts with p107. , 1994, Genes & development.

[30]  L. Zhu,et al.  E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. , 1994, Genes & development.

[31]  A. Zetterberg,et al.  Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[32]  A. Pardee,et al.  A restriction point for control of normal animal cell proliferation. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[33]  H. Hochegger,et al.  Degron Tagging Using mAID and SMASh Tags in RPE-1 Cells. , 2022, Methods in molecular biology.