Influence of escitalopram treatment on 5-HT1A receptor binding in limbic regions in patients with anxiety disorders

[1]  Rupert Lanzenberger,et al.  Simple and fully automated preparation of [carbonyl-11C]WAY-100635 , 2007 .

[2]  R. P. Maguire,et al.  Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[3]  Wolfgang Wadsak,et al.  Reduced Serotonin-1A Receptor Binding in Social Anxiety Disorder , 2007, Biological Psychiatry.

[4]  Johan Gabrielsson,et al.  Mechanistic model of acute autoinhibitory feedback action after administration of SSRIs in rats: application to escitalopram-induced effects on brain serotonin levels. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[5]  C. Sánchez The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. , 2006, Basic & clinical pharmacology & toxicology.

[6]  R Todd Ogden,et al.  Lower serotonin transporter binding potential in the human brain during major depressive episodes. , 2006, The American journal of psychiatry.

[7]  J. A. Boer,et al.  Effect of Increased Serotonin Levels on [18F]MPPF Binding in Rat Brain: Fenfluramine vs the Combination of Citalopram and Ketanserin , 2005, Neuropsychopharmacology.

[8]  P. Blier,et al.  Responsiveness of 5-HT(1A) and 5-HT2 receptors in the rat orbitofrontal cortex after long-term serotonin reuptake inhibition. , 2005, Journal of psychiatry & neuroscience : JPN.

[9]  Sean P David,et al.  A Functional Genetic Variation of the Serotonin (5-HT) Transporter Affects 5-HT1A Receptor Binding in Humans , 2005, The Journal of Neuroscience.

[10]  Dan J Stein,et al.  Escitalopram in the treatment of social anxiety disorder , 2005, British Journal of Psychiatry.

[11]  S. Keam,et al.  Escitalopram , 2012, Drugs.

[12]  K. Lesch,et al.  Long-term fluoxetine treatment decreases 5-HT1A receptor responsivity in obsessive-compulsive disorder , 2005, Psychopharmacology.

[13]  Sati Mazumdar,et al.  Serotonin 1A Receptor Binding and Treatment Response in Late-Life Depression , 2004, Neuropsychopharmacology.

[14]  P. Cowen,et al.  Preferential 5-HT1A Autoreceptor Occupancy by Pindolol is Attenuated in Depressed Patients: Effect of Treatment or an Endophenotype of Depression? , 2004, Neuropsychopharmacology.

[15]  C. Halldin,et al.  Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain , 2004, Human brain mapping.

[16]  Laurent Descarries,et al.  Toward brain imaging of serotonin 5-HT1A autoreceptor internalization , 2004, NeuroImage.

[17]  Rene Hen,et al.  The developmental origins of anxiety , 2004, Nature Reviews Neuroscience.

[18]  Laurent Descarries,et al.  Acute Treatment with the Antidepressant Fluoxetine Internalizes 5-HT1A Autoreceptors and Reduces the In Vivo Binding of the PET Radioligand [18F]MPPF in the Nucleus Raphe Dorsalis of Rat , 2004, The Journal of Neuroscience.

[19]  S. Caccia,et al.  Effects of chronic treatment with escitalopram or citalopram on extracellular 5‐HT in the prefrontal cortex of rats: role of 5‐HT1A receptors , 2004, British journal of pharmacology.

[20]  P. Grasby,et al.  Occupancy of Agonist Drugs at the 5-HT1A Receptor , 2004, Neuropsychopharmacology.

[21]  P A Sargent,et al.  Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635 , 2004, Molecular Psychiatry.

[22]  Peter Herscovitch,et al.  Reduced Serotonin Type 1A Receptor Binding in Panic Disorder , 2004, The Journal of Neuroscience.

[23]  L. Lanfumey,et al.  Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine , 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

[24]  Dan J Stein,et al.  Escitalopram in the treatment of social anxiety disorder: Analysis of efficacy for different clinical subgroups and symptom dimensions , 2004, Depression and anxiety.

[25]  C. Sánchez,et al.  Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities , 2003, Psychopharmacology.

[26]  L. Culpepper Escitalopram: A New SSRI for the Treatment of Depression in Primary Care. , 2002, Primary care companion to the Journal of clinical psychiatry.

[27]  Victoria Arango,et al.  Effects of sex, age, and aggressive traits in man on brain serotonin 5-HT1A receptor binding potential measured by PET using [C-11]WAY-100635 , 2002, Brain Research.

[28]  R. Adolphs Neural systems for recognizing emotion , 2002, Current Opinion in Neurobiology.

[29]  René Hen,et al.  Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult , 2002, Nature.

[30]  Roger N. Gunn,et al.  A Database of [11C]WAY-100635 Binding to 5-HT1A Receptors in Normal Male Volunteers: Normative Data and Relationship to Methodological, Demographic, Physiological, and Behavioral Variables , 2002, NeuroImage.

[31]  J Tauscher,et al.  Inverse relationship between serotonin 5-HT(1A) receptor binding and anxiety: a [(11)C]WAY-100635 PET investigation in healthy volunteers. , 2001, The American journal of psychiatry.

[32]  R Myers,et al.  Effect of 5‐HT on binding of [11C] WAY 100635 to 5‐HT1A receptors in rat brain, assessed using in vivo microdialysis and PET after fenfluramine , 2001, Synapse.

[33]  H Fischer,et al.  Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study. , 2001, The American journal of psychiatry.

[34]  E. Maguire,et al.  Methods for developmental studies of fear conditioning circuitry , 2001, Biological Psychiatry.

[35]  H. Rollema,et al.  Activation of postsynaptic 5‐HT1A receptors by fluoxetine despite the loss of firing‐dependent serotonergic input: Electrophysiological and neurochemical studies , 2001, Synapse.

[36]  Shitij Kapur,et al.  Serotonin 5-HT1A Receptor Binding Potential Declines with Age as Measured by [11C]WAY-100635 and PET , 2001, Neuropsychopharmacology.

[37]  H. Wikström,et al.  Acute and chronic effects of citalopram on postsynaptic 5‐hydroxytryptamine1A receptor‐mediated feedback: a microdialysis study in the amygdala , 2001, Journal of neurochemistry.

[38]  Alan A. Wilson,et al.  The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study. , 2001, The American journal of psychiatry.

[39]  P. Fox,et al.  Differential limbic–cortical correlates of sadness and anxiety in healthy subjects: implications for affective disorders , 2000, Biological Psychiatry.

[40]  P A Sargent,et al.  Brain serotonin1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment. , 2000, Archives of general psychiatry.

[41]  D. Kupfer,et al.  Pet imaging of serotonin 1A receptor binding in depression , 1999, Biological Psychiatry.

[42]  P. Blier,et al.  Autoregulation of serotonin neurons: role in antidepressant drug action. , 1999, Pharmacological reviews.

[43]  K. Lesch,et al.  5-HT1A Receptor Function in Normal Subjects on Clinical Doses of Fluoxetine: Blunted Temperature and Hormone Responses to Ipsapirone Challenge , 1999, Neuropsychopharmacology.

[44]  Ralph Myers,et al.  Assessment of Spatial Normalization of PET Ligand Images Using Ligand-Specific Templates , 1999, NeuroImage.

[45]  Wolfgang Grodd,et al.  Subcortical correlates of differential classical conditioning of aversive emotional reactions in social phobia , 1999, Biological Psychiatry.

[46]  E. Azmitia,et al.  Agonist‐ and antagonist‐induced plasticity of rat 5‐HT1A receptor in hippocampal cell culture , 1999, Synapse.

[47]  Robert B. Innis,et al.  Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography. , 1998, Clinical positron imaging : official journal of the Institute for Clinical P.E.T.

[48]  T. Hergueta,et al.  The mini international neuropsychiatric interview , 1998, European Psychiatry.

[49]  C Burger,et al.  A JAVA environment for medical image data analysis: initial application for brain PET quantitation. , 1998, Medical informatics = Medecine et informatique.

[50]  D. Sheehan,et al.  The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. , 1998, The Journal of clinical psychiatry.

[51]  L. Lanfumey,et al.  Fluoxetine‐induced desensitization of somatodendritic 5‐HT1A autoreceptors is independent of glucocorticoid(s) , 1997, Synapse.

[52]  L. D. van de Kar,et al.  A desensitization of hypothalamic 5-HT1A receptors by repeated injections of paroxetine: reduction in the levels of G(i) and G(o) proteins and neuroendocrine responses, but not in the density of 5-HT1A receptors. , 1997, The Journal of pharmacology and experimental therapeutics.

[53]  Paul J. Harrison,et al.  [3H]WAY–100635 for 5–HT1A receptor autoradiography in human brain: a comparison with [3H]8–OH–DPAT and demonstration of increased binding in the frontal cortex in schizophrenia , 1997, Neurochemistry International.

[54]  S. Beck,et al.  Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. , 1997, The Journal of pharmacology and experimental therapeutics.

[55]  H. Wikström,et al.  Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]WAY-100635 , 1997, Brain Research.

[56]  A. Lammertsma,et al.  Simplified Reference Tissue Model for PET Receptor Studies , 1996, NeuroImage.

[57]  L. D. van de Kar,et al.  Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist. , 1996, The Journal of pharmacology and experimental therapeutics.

[58]  E. Azmitia,et al.  Increased 5-HT1A receptor immunoreactivity in the rat hippocampus following 5,7-dihydroxytryptamine lesions in the cingulum bundle and fimbria-fornix , 1995, Behavioural Brain Research.

[59]  C. Montigny,et al.  Current advances and trends in the treatment of depression. , 1994, Trends in pharmacological sciences.

[60]  V. Klimek,et al.  EFFECTS OF REPEATED TREATMENT WITH FLUOXETINE AND CITALOPRAM, A 5‐HT UPTAKE INHIBITORS ON 5‐HT1A AND 5‐HT2 RECEPTORS IN THE RAT BRAIN. , 1994, Journal of psychiatry & neuroscience : JPN.

[61]  Karl J. Friston,et al.  Statistical parametric maps in functional imaging: A general linear approach , 1994 .

[62]  B. Lerer,et al.  Regulation of 5-hydroxytryptamine1A receptor function in rat hippocampus by short- and long-term administration of 5-hydroxytryptamine1A agonist and antidepressants. , 1992, The Journal of pharmacology and experimental therapeutics.

[63]  J. Davis,et al.  Similar effects of treatment with desipramine and electroconvulsive shock on 5-hydroxytryptamine1A receptors in rat brain. , 1991, European journal of pharmacology.

[64]  J. Bockaert,et al.  5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists. , 1991, The Journal of pharmacology and experimental therapeutics.

[65]  K. Lesch 5-HT1A receptor responsivity in anxiety disorders and depression. , 1991, Progress in neuro-psychopharmacology & biological psychiatry.

[66]  G. Halliday,et al.  Cytoarchitecture of the human dorsal raphe nucleus , 1990, The Journal of comparative neurology.

[67]  J. Leysen,et al.  5‐HT2 Receptors, Roles and Regulation , 1990, Annals of the New York Academy of Sciences.

[68]  S. Svebak,et al.  Clonazepam and imipramine in the treatment of panic attacks: a double-blind comparison of efficacy and side effects. , 1990, The Journal of clinical psychiatry.

[69]  C. de Montigny,et al.  A role for the serotonin system in the mechanism of action of antidepressant treatments: preclinical evidence. , 1990, The Journal of clinical psychiatry.

[70]  C. Spielberger,et al.  Psychometric properties of the STAI: a reply to Ramanaiah, Franzen, and Schill. , 1984, Journal of personality assessment.