Somatostatin and SMS 201-995 reverse the impairment of cognitive functions induced by cysteamine depletion of brain somatostatin.

[1]  Botond Penke,et al.  Somatostatin and (d-TRP8, d-CYS14)-somatostatin delay extinction and reverse electroconvulsive shock induced amnesia in rats , 1986, Psychoneuroendocrinology.

[2]  J. Puymirat,et al.  Patients with Alzheimer's disease show an increased content of 15 Kdalton somatostatin precursor and a lowered level of tetradecapeptide in their cerebrospinal fluid. , 1986, Life sciences.

[3]  S. Lamberts,et al.  The somatostatin analog SMS 201-995 induces long-acting inhibition of growth hormone secretion without rebound hypersecretion in acromegalic patients. , 1985, The Journal of clinical endocrinology and metabolism.

[4]  F. Bloom,et al.  Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients , 1985, Nature.

[5]  T. Crow,et al.  Location of neuronal tangles in somatostatin neurones in Alzheimer's disease , 1985, Nature.

[6]  R. Joynt,et al.  Neuropeptides in aging and dementia , 1984, Peptides.

[7]  B. Penke,et al.  Comparative studies with somatostatin and cysteamine in different behavioral tests on rats , 1984, Pharmacology Biochemistry and Behavior.

[8]  C. B. Srikant,et al.  Cysteamine-induced depletion of brain somatostatin is associated with up-regulation of cerebrocortical somatostatin receptors. , 1984, Endocrinology.

[9]  L. Vécsei,et al.  The effect of somatostatin on self-stimulation behavior in atropine- and methysergide-pretreated rats. , 1983, European journal of pharmacology.

[10]  L. Vécsei,et al.  Intracerebroventricular somatostatin attenuates electroconvulsive shock-induced amnesia in rats , 1983, Peptides.

[11]  F. Bloom,et al.  Effects of cysteamine on pro-somatostatin related peptides , 1983, Regulatory Peptides.

[12]  L. Swanson,et al.  Biological effects of cysteamine: relationship to somatostatin depletion , 1983, Regulatory Peptides.

[13]  P. Marbach,et al.  SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action. , 1982, Life sciences.

[14]  S. Szabó,et al.  Selective depletion of somatostatin in rat brain by cysteamine , 1982, Brain Research.

[15]  J. B. Martin,et al.  Depletion of somatostatin-like immunoreactivity in the rat central nervous system by cysteamine , 1982, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[16]  S. Szabó,et al.  Somatostatin in rat tissues is depleted by cysteamine administration. , 1981, Endocrinology.

[17]  L. Iversen,et al.  Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type , 1980, Neuroscience Letters.

[18]  R. Katzman.,et al.  Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa , 1980, Nature.

[19]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[20]  A. Kastin,et al.  Growth hormone release inhibiting hormone: neuropharmacological studies. , 1974, Pharmacology, biochemistry, and behavior.

[21]  C. Londos,et al.  A highly sensitive adenylate cyclase assay. , 1974, Analytical biochemistry.

[22]  R. Wurtman,et al.  A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. , 1967, Life sciences.

[23]  L. Vécsei,et al.  Dose-related effects of cysteamine treatment on hypothalamic and striatal dopamine, noradrenaline and serotonin neurotransmission. , 1985, Acta physiologica Hungarica.

[24]  M. Neufeld,et al.  Clinical applications of somatostatin analogs. , 1985, Advances in experimental medicine and biology.

[25]  L. Vécsei,et al.  Comparative studies with cyclic and linear somatostatin on active avoidance behaviour and open-field activity in rats. , 1983, Acta physiologica Hungarica.

[26]  L. Vécsei,et al.  The effect of linear somatostatin on the active avoidance behaviour and open-field activity on haloperidol, phenoxybenzamine and atropine pretreated rats. , 1983, Acta physiologica Hungarica.

[27]  L. Vécsei,et al.  The effect of somatostatin on the self-stimulation of rats , 1982 .