Is a new COVID‐19 wave coming from China due to an unknown variant of concern? Keep calm and look at the data

Supported by the GISAID data, we discuss on the more or less probable increase in the number of COVID-19 cases in the very next future. Currently, all the sequenced case in Europe, USA and Asia refer to Omicron-related variants and recombinations. Accordingly, the increasing in the attention to the Covid situation is currently not justified by looking at the available indicators and at the current variants of concern recorded worldwide This article is protected by copyright. All rights reserved.

[1]  R. G. Clark,et al.  Surveillance for SARS‐CoV‐2 and its variants in wastewater of tertiary care hospitals correlates with increasing case burden and outbreaks , 2022, Journal of medical virology.

[2]  S. Pascarella,et al.  Genome-based comparison between the recombinant SARS-CoV-2 XBB and its parental lineages , 2022, bioRxiv.

[3]  M. Falcone,et al.  Efficacy and Safety of Nirmatrelvir/Ritonavir, Molnupiravir, and Remdesivir in a Real-World Cohort of Outpatients with COVID-19 at High Risk of Progression: The PISA Outpatient Clinic Experience , 2022, Infectious Diseases and Therapy.

[4]  S. Pascarella,et al.  Genetic and Structural Data on the SARS-CoV-2 Omicron BQ.1 Variant Reveal Its Low Potential for Epidemiological Expansion , 2022, bioRxiv.

[5]  B. Cowling,et al.  Transmission dynamics of SARS-CoV-2 Omicron variant infections in Hangzhou, Zhejiang, China, January-February 2022 , 2022, International Journal of Infectious Diseases.

[6]  S. Pascarella,et al.  On the SARS‐CoV‐2 BA.2.75 variant: A genetic and structural point of view , 2022, Journal of medical virology.

[7]  A. Maruotti,et al.  Genomic Epidemiology Unveil the Omicron Transmission Dynamics in Rome, Italy , 2022, Pathogens.

[8]  B. La Scola,et al.  SARS-CoV-2 Testing of Aircraft Wastewater Shows That Mandatory Tests and Vaccination Pass before Boarding Did Not Prevent Massive Importation of Omicron Variant into Europe , 2022, Viruses.

[9]  S. Mazzoli,et al.  Predicting the Spread of SARS-CoV-2 in Italian Regions: The Calabria Case Study, February 2020–March 2022 , 2022, Diseases.

[10]  E. Lau,et al.  Epidemiology of Infections with SARS-CoV-2 Omicron BA.2 Variant, Hong Kong, January–March 2022 , 2022, medRxiv.

[11]  M. Perc,et al.  Risk assessment of COVID-19 epidemic resurgence in relation to SARS-CoV-2 variants and vaccination passes , 2022, Communications Medicine.

[12]  J. Wallinga,et al.  Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021 , 2022, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[13]  A. Maruotti,et al.  Prisoners of variants, or free to act as prisoners of swabs? The case of Italy , 2022, Journal of Medical Virology.

[14]  M. Falcone,et al.  Early Use of Remdesivir and Risk of Disease Progression in Hospitalized Patients With Mild to Moderate COVID-19 , 2022, Clinical Therapeutics.

[15]  Liyuan Liu,et al.  Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2 , 2021, Nature.

[16]  C. Mussini,et al.  What have we learned from the first to the second wave of COVID-19 pandemic? An international survey from the ESCMID Study Group for Infection in the Elderly (ESGIE) group , 2021, European Journal of Clinical Microbiology & Infectious Diseases.

[17]  S. Mallapaty.  China’s COVID vaccines have been crucial — now immunity is waning , 2021, Nature.

[18]  M. Pistello,et al.  Efficacy of Bamlanivimab/Etesevimab and Casirivimab/Imdevimab in Preventing Progression to Severe COVID-19 and Role of Variants of Concern , 2021, Infectious Diseases and Therapy.

[19]  A. Maruotti,et al.  While we are discussing… the SARS‐CoV‐2 virus laughs , 2021, Journal of Medical Virology.

[20]  André Calero Valdez,et al.  A look into the future of the COVID-19 pandemic in Europe: an expert consultation , 2021, The Lancet Regional Health - Europe.

[21]  Antonello Maruotti,et al.  Nowcasting COVID‐19 incidence indicators during the Italian first outbreak , 2020, Statistics in medicine.