Cell lineage allocation within the inner cell mass of the mouse blastocyst.

[1]  Jennifer Nichols,et al.  Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo , 2012, Development.

[2]  Anna-Katerina Hadjantonakis,et al.  The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17. , 2011, Developmental biology.

[3]  Periklis Pantazis,et al.  Oct4 kinetics predict cell lineage patterning in the early mammalian embryo , 2011, Nature Cell Biology.

[4]  Janet Rossant,et al.  The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. , 2010, Developmental cell.

[5]  A. Hadjantonakis,et al.  A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst , 2010, Development.

[6]  Janet Rossant,et al.  The role of FGF/Erk signaling in pluripotent cells , 2010, Development.

[7]  Alexander W. Bruce,et al.  Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate. , 2010, Current opinion in genetics & development.

[8]  M. Zernicka-Goetz,et al.  Stochasticity versus determinism in development: a false dichotomy? , 2010, Nature Reviews Genetics.

[9]  A. Hadjantonakis,et al.  Cellular dynamics in the early mouse embryo: from axis formation to gastrulation. , 2010, Current opinion in genetics & development.

[10]  R. Kemler,et al.  Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism. , 2010, Developmental biology.

[11]  B. Seed,et al.  The transcription factor MAFB antagonizes anti-viral responses by blockade of coactivator recruitment to IRF3 , 2010, Nature Immunology.

[12]  Mikael Huss,et al.  Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. , 2010, Developmental cell.

[13]  Samantha A. Morris,et al.  Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo , 2010, Proceedings of the National Academy of Sciences.

[14]  Janet Rossant,et al.  FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst , 2010, Development.

[15]  Kit T. Rodolfa,et al.  Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. , 2010, Genes & development.

[16]  J. Rossant,et al.  Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2 , 2010, Development.

[17]  J. Nichols,et al.  Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo , 2009, Development.

[18]  Samantha A. Morris,et al.  Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst. , 2009, Developmental biology.

[19]  Samantha A. Morris,et al.  Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo , 2009, Nature Reviews Genetics.

[20]  C. Lim,et al.  Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells , 2009, PLoS biology.

[21]  Janet Rossant,et al.  The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. , 2009, Developmental cell.

[22]  Janet Rossant,et al.  Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse , 2009, Development.

[23]  Elizabeth J. Robertson,et al.  Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo , 2009, Nature Reviews Molecular Cell Biology.

[24]  A. Tarkowski,et al.  Blastomeres of the mouse embryo lose totipotency after the fifth cleavage division: expression of Cdx2 and Oct4 and developmental potential of inner and outer blastomeres of 16- and 32-cell embryos. , 2008, Developmental biology.

[25]  Guoji Guo,et al.  Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo. , 2008, Genes & development.

[26]  Anna-Katerina Hadjantonakis,et al.  Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst , 2008, Development.

[27]  N. D. Clarke,et al.  Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells , 2008, Cell.

[28]  Shinji Yamamoto,et al.  Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos , 2008, Mechanisms of Development.

[29]  Janet Rossant,et al.  Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst. , 2008, Developmental biology.

[30]  Janet Rossant,et al.  Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. , 2008, Developmental biology.

[31]  J. Nichols,et al.  Nanog safeguards pluripotency and mediates germline development , 2007, Nature.

[32]  Takashi Hiiragi,et al.  Stochastic patterning in the mouse pre-implantation embryo , 2007, Development.

[33]  M. DePamphilis,et al.  Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development , 2007, Development.

[34]  N. Terada,et al.  A Heterogeneous Expression Pattern for Nanog in Embryonic Stem Cells , 2007, Stem cells.

[35]  M. Zernicka-Goetz,et al.  Histone arginine methylation regulates pluripotency in the early mouse embryo , 2007, Nature.

[36]  Tony Pawson,et al.  Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. , 2006, Developmental cell.

[37]  Janet Rossant,et al.  Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation , 2005, Cell.

[38]  Janet Rossant,et al.  Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst , 2005, Development.

[39]  M. Zernicka-Goetz,et al.  The first cleavage of the mouse zygote predicts the blastocyst axis , 2005, Nature.

[40]  P. Murray,et al.  Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates , 2004, Development.

[41]  Austin G Smith,et al.  Self-renewal of teratocarcinoma and embryonic stem cells , 2004, Oncogene.

[42]  D. Scherman,et al.  Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties , 2003, BMC biotechnology.

[43]  M. Murakami,et al.  The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells , 2003, Cell.

[44]  J. Nichols,et al.  Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.

[45]  W. D. Martin,et al.  Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis. , 2002, Developmental biology.

[46]  P. Murray,et al.  Regulation of the differentiation and behaviour of extra-embryonic endodermal cells by basement membranes. , 2001, Journal of cell science.

[47]  F. Grosveld,et al.  The transcription factor GATA6 is essential for early extraembryonic development. , 1999, Development.

[48]  Tony Pawson,et al.  Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation , 1998, Cell.

[49]  E. Morrisey,et al.  GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. , 1998, Genes & development.

[50]  H. Schöler,et al.  Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 , 1998, Cell.

[51]  J. Heath,et al.  Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[52]  M. Capecchi,et al.  Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. , 1997, Developmental biology.

[53]  E. Olson,et al.  Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. , 1997, Genes & development.

[54]  K Sigrist,et al.  GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. , 1997, Genes & development.

[55]  N. Corbi,et al.  Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. , 1995, Genes & development.

[56]  R. Fässler,et al.  Consequences of lack of beta 1 integrin gene expression in mice. , 1995, Genes & development.

[57]  R. Pedersen,et al.  Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality. , 1995, Genes & development.

[58]  V. Papaioannou,et al.  Requirement of FGF-4 for postimplantation mouse development , 1995, Science.

[59]  H. Schöler,et al.  Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. , 1994, Developmental biology.

[60]  S. Becker,et al.  Localization of endoderm-specific mRNAs in differentiating F9 embryoid bodies , 1992, Mechanisms of Development.

[61]  J. C. Chisholm,et al.  Cytokeratin filament assembly in the preimplantation mouse embryo. , 1987, Development.

[62]  C. Ziomek,et al.  The foundation of two distinct cell lineages within the mouse morula , 1981, Cell.

[63]  A. Enders,et al.  Differentiation and migration of endoderm in the rat and mouse at implantation , 1978, The Anatomical record.

[64]  S. Kelly Studies of the developmental potential of 4- and 8-cell stage mouse blastomeres. , 1977, The Journal of experimental zoology.

[65]  M. Evans,et al.  Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[66]  A. Tarkowski,et al.  Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage. , 1967, Journal of embryology and experimental morphology.

[67]  Xiao-Fan Wang,et al.  Signaling cross-talk between TGF-β/BMP and other pathways , 2009, Cell Research.

[68]  A. Tarkowski,et al.  Erratum to “Blastomeres of the mouse embryo lose totipotency after the fifth cleavage division: Expression of Cdx2 and Oct4 and developmental potential of inner and outer blastomeres of 16- and 32-cell embryos” [Dev. Biol. 322 (2008) 133–144] , 2009 .

[69]  R. Lovell-Badge,et al.  Multipotent cell lineages in early mouse development depend on SOX2 function. , 2003, Genes & development.

[70]  R. Gardner,et al.  Can developmentally significant spatial patterning of the egg be discounted in mammals? , 1996, Human reproduction update.