Optofluidic particle manipulation in a liquid-core/liquid-cladding waveguide.

This paper describes a method for particle manipulation in a liquid-core/liquid-cladding optical waveguide system. Step-index and graded-index waveguides were modeled with consideration for, respectively, miscible and immiscible core and cladding fluids. The characteristic motions of four different particles with refractive indices of 1.59, 1.48, 1.37, and 1.22 were examined. The guided beam was assumed to be Gaussian in shape. Our results showed that high-refractive-index particles converged at the center of the core fluid due to a positive gradient force, whereas low-refractive-index particles converged at the flow periphery. The nonlinearity of the particle motion increased as the flow velocity and the guided beam waist decreased and the laser power and the particle size increased. The initial beam waist of the guided beam in the graded-index waveguide did not significantly affect the characteristics of the particle motion due to the effects of diffusion.

[1]  Young Ki Hahn,et al.  Label-free cell separation using a tunable magnetophoretic repulsion force. , 2012, Analytical chemistry.

[2]  David Erickson,et al.  Controlled photonic manipulation of proteins and other nanomaterials. , 2012, Nano letters.

[3]  Ian M. White,et al.  Optofluidic SERS: synergizing photonics and microfluidics for chemical and biological analysis , 2012 .

[4]  H. Sung,et al.  Radiation forces on a microsphere in an arbitrary refractive index profile , 2012 .

[5]  J. Tegenfeldt,et al.  Sorting cells by size, shape and deformability. , 2012, Lab on a chip.

[6]  E. Boczko,et al.  Simultaneous on-chip DC dielectrophoretic cell separation and quantitative separation performance characterization. , 2012, Analytical chemistry.

[7]  H. Sung,et al.  Assessment of cross-type optical particle separation system , 2012 .

[8]  Qi Jie Wang,et al.  A tunable 3D optofluidic waveguide dye laser via two centrifugal Dean flow streams. , 2011, Lab on a chip.

[9]  I-Kao Chiang,et al.  Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW). , 2011, Lab on a chip.

[10]  Alex Terray,et al.  Toward label-free optical fractionation of blood--optical force measurements of blood cells. , 2011, Analytical chemistry.

[11]  Hyung Jin Sung,et al.  Enhancement by optical force of separation in pinched flow fractionation. , 2011, Lab on a chip.

[12]  S. Hart,et al.  On-the-fly cross flow laser guided separation of aerosol particles based on size, refractive index and density-theoretical analysis. , 2010, Optics express.

[13]  Yuqiang Jiang,et al.  Nonlinear optical effects in trapping nanoparticles with femtosecond pulses , 2010 .

[14]  Andrew A. Bettiol,et al.  A microfluidic device with integrated optics for microparticle switching , 2010 .

[15]  Hyung Jin Sung,et al.  Three-dimensional microfluidic liquid-core/liquid-cladding waveguide , 2010 .

[16]  Ethan Schonbrun,et al.  Optical manipulation with planar silicon microring resonators. , 2010, Nano letters.

[17]  Yu-Hwa Lo,et al.  Human mammalian cell sorting using a highly integrated micro-fabricated fluorescence-activated cell sorter (microFACS). , 2010, Lab on a chip.

[18]  Aram J. Chung,et al.  Analysis of liquid-to-solid coupling and other performance parameters for microfluidically reconfigurable photonic systems. , 2010, Optics express.

[19]  R. Marie,et al.  Optofluidic microscope with 3D spatial resolution. , 2010, Optics express.

[20]  Demetri Psaltis,et al.  Pneumatically tunable optofluidic dye laser , 2010 .

[21]  Ming Lei,et al.  Trapping of low-refractive-index particles with azimuthally polarized beam , 2009 .

[22]  M. Vellekoop,et al.  A versatile liquid-core/liquid-twin-cladding waveguide micro flow cell fabricated by rapid prototyping , 2009 .

[23]  H. Sung,et al.  Nondimensional analysis of particle behavior during cross-type optical particle separation. , 2009, Applied optics.

[24]  Demetri Psaltis,et al.  Optofluidic evanescent dye laser based on a distributed feedback circular grating , 2009 .

[25]  Seung-Man Yang,et al.  Fluorescent liquid-core/air-cladding waveguides toward integrated optofluidic light sources , 2008, NanoScience + Engineering.

[26]  P. Sarro,et al.  Liquid-core/liquid-cladding integrated silicon ARROW waveguides , 2008 .

[27]  Hyung Jin Sung,et al.  Cross-type optical particle separation in a microchannel. , 2008, Analytical chemistry.

[28]  D. Erickson,et al.  Optofluidic transport in liquid core waveguiding structures , 2007 .

[29]  George M. Whitesides,et al.  Integrated fluorescent light source for optofluidic applications , 2005 .

[30]  J. Wilkinson,et al.  Sorting of polystyrene microspheres using a Y-branched optical waveguide. , 2005, Optics express.

[31]  Elinore M Mercer,et al.  Microfluidic sorting of mammalian cells by optical force switching , 2005, Nature Biotechnology.

[32]  J. Squier,et al.  Optical trapping, manipulation, and sorting of cells and colloids in microfluidic systems with diode laser bars , 2004, (CLEO). Conference on Lasers and Electro-Optics, 2005..

[33]  G. Whitesides,et al.  Dynamic control of liquid-core/liquid-cladding optical waveguides , 2004, (CLEO). Conference on Lasers and Electro-Optics, 2005..

[34]  W Sibbett,et al.  Manipulation and filtration of low index particles with holographic Laguerre-Gaussian optical trap arrays. , 2004, Optics express.

[35]  Grover A. Swartzlander,et al.  Trapping of low-index microparticles in an optical vortex , 1998 .

[36]  T. Imasaka,et al.  Theory of optical chromatography. , 1997, Analytical chemistry.

[37]  A. Ashkin Forces of a single-beam gradient laser trap on a dielectric sphere in the ray optics regime. , 1992, Methods in cell biology.

[38]  M. Lipson,et al.  Optical manipulation of nanoparticles and biomolecules in sub-wavelength slot waveguides , 2009, Nature.

[39]  Holger Schmidt,et al.  Optofluidic waveguides: I. Concepts and implementations , 2008, Microfluidics and nanofluidics.