Adolescent Hypertension and Risk for Early-Onset Type 2 Diabetes: A Nationwide Study of 1.9 Million Israeli Adolescents.

The incidence of adolescent hypertension is growing worldwide, mostly in conjunction with the growing obesity prevalence (1,2). Adolescent hypertension was shown to be a risk factor for cardiovascular and renal outcomes later in life, thus promoting current guidelines to screen all pediatric and adolescent population for hypertension (1,3). Here, we elucidate the association of adolescent hypertension and early-onset type 2 diabetes in a nationwide cohort of adolescents. In this population-based, retrospec-tive cohort study we linked the Israeli Defense Forces conscription center da-tabase with the Israeli National Diabetes Registry (INDR). One year prior to man-datory military at age 17 years, Israeli adolescents undergo comprehen-sive medical evaluation based on their history, an interview and phys-ical that measurements of height, weight, and blood pressure. Included were adolescents 1993 and 31 December 2016. Excluded were those with prior diagnosis of dys-glycemia andthosewithmissing baseline height or weight data (3.8% in total).